Total Holdings
6
Positions in the fund
ProShares UltraShort Nasdaq Biotechnology
BISNASDAQProSharesEquity
$11.19Today:- (-)1Y −4.60%
As of Oct 22, 2026 close
- Assets (AUM)
- $1.94M
- Expense ratio
- 0.95%
- Dividend yield
- 5.52%
- Holdings
- 6
- 52-week range
- $8.31$20.00
- Volume (live)
- -
- Avg. volume (3M)
- 9.50K
BIS ETF Holdings: ProShares UltraShort Nasdaq Biotechnology
Every listed position with its portfolio weight, plus sector breakdown and geographic exposure for this Equity ETF. Analyze fund diversification and concentration.
Top 10 Holdings
48.0%
Share of fund assets
Assets (AUM)
$1.94M
Total fund assets
Expense Ratio
0.95%
Annual management fee
Portfolio Allocations
Distribution breakdown by sector, asset type, and geographic region. Understand the fund's diversification strategy across markets and asset classes.
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All 48 BIS Holdings by Portfolio Weight
Ticker, name, asset type and portfolio weight for each position.
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| # | Symbol | Name | Type | Weight |
|---|---|---|---|---|
| 1 |  | Amgen Inc | Stock | 8.14% |
| 2 |  | Gilead Sciences, Inc | Stock | 7.41% |
| 3 |  | Vertex Pharmaceuticals Incorporated | Stock | 7.21% |
| 4 |  | Biogen Inc | Stock | 6.12% |
| 5 |  | Illumina, Inc | Stock | 5.67% |
| 6 |  | Regeneron Pharmaceuticals, Inc | Stock | 4.13% |
| 7 | ALXN | Alexion Pharmaceuticals, Inc | Stock | 3.02% |
| 8 | SGEN | Seagen Inc | Stock | 2.25% |
| 9 |  | Incyte Corporation | Stock | 2.09% |
| 10 |  | BioMarin Pharmaceutical Inc | Stock | 1.91% |
| 11 |  | Alnylam Pharmaceuticals, Inc | Stock | 1.60% |
| 12 | MYL | Viatris Inc | Stock | 1.35% |
| 13 |  | Sanofi | Stock | 1.29% |
| 14 |  | Neurocrine Biosciences, Inc | Stock | 1.16% |
| 15 |  | Sarepta Therapeutics, Inc | Stock | 1.15% |
| 16 |  | NovoCure Limited | Stock | 1.10% |
| 17 |  | Jazz Pharmaceuticals plc | Stock | 1.03% |
| 18 |  | Ionis Pharmaceuticals, Inc | Stock | 1.02% |
| 19 |  | Bio-Techne Corporation | Stock | 1.02% |
| 20 |  | Guardant Health, Inc | Stock | 0.96% |
| 21 | HZNP | Horizon Therapeutics Public Limited Company | Stock | 0.87% |
| 22 |  | Amarin Corporation plc | Stock | 0.85% |
| 23 |  | Moderna, Inc | Stock | 0.83% |
| 24 | BGNE | BeiGene, Ltd | Stock | 0.83% |
| 25 | PRAH | PRA Health Sciences, Inc | Stock | 0.81% |
| 26 |  | ACADIA Pharmaceuticals Inc | Stock | 0.81% |
| 27 | SYNH | Syneos Health, Inc | Stock | 0.80% |
| 28 |  | Ascendis Pharma AS | Stock | 0.77% |
| 29 |  | Exelixis, Inc | Stock | 0.73% |
| 30 | RETA | Reata Pharmaceuticals, Inc | Stock | 0.70% |
| 31 | BLUE | bluebird bio, Inc | Stock | 0.65% |
| 32 |  | Arrowhead Pharmaceuticals, Inc | Stock | 0.65% |
| 33 | GBT | Global Blood Therapeutics, Inc | Stock | 0.61% |
| 34 | CBPO | China Biologic Products Holdings Inc | Stock | 0.54% |
| 35 |  | BridgeBio Pharma, Inc | Stock | 0.51% |
| 36 | ALLK | Allakos Inc | Stock | 0.49% |
| 37 |  | United Therapeutics Corporation | Stock | 0.49% |
| 38 |  | Nektar Therapeutics | Stock | 0.48% |
| 39 | BPMC | Blueprint Medicines Corporation | Stock | 0.48% |
| 40 | SAGE | Sage Therapeutics, Inc | Stock | 0.48% |
| 41 | FGEN | FibroGen, Inc | Stock | 0.47% |
| 42 | MRTX | Mirati Therapeutics, Inc | Stock | 0.46% |
| 43 | IMMU | Immunomedics, Inc | Stock | 0.44% |
| 44 | DCPH | Deciphera Pharmaceuticals, Inc | Stock | 0.43% |
| 45 |  | Agios Pharmaceuticals, Inc | Stock | 0.43% |
| 46 | ICPT | Intercept Pharmaceuticals, Inc | Stock | 0.42% |
| 47 |  | Adaptive Biotechnologies Corporation | Stock | 0.42% |
| 48 |  | Ultragenyx Pharmaceutical Inc | Stock | 0.42% |
Source: Fund holdings disclosures. Data sources and methodology
Frequently Asked Questions About ProShares UltraShort Nasdaq Biotechnology Holdings
What are the top holdings in BIS?
ProShares UltraShort Nasdaq Biotechnology (BIS) holds 6 securities. The largest are Amgen Inc (8.14%), Gilead Sciences, Inc (7.41%), Vertex Pharmaceuticals Incorporated (7.21%). The holdings table lists each position by portfolio weight with its ticker, name and asset type.
How concentrated is BIS's portfolio?
The 10 largest positions make up 48.0% of BIS's assets. A concentrated portfolio has fewer large positions with higher individual weights, while a diversified portfolio distributes holdings more evenly.
What is BIS's sector allocation?
The Sector Allocation chart shows how BIS distributes investments across different industries like Technology, Healthcare, Financials, and more. This sector exposure helps understand the fund's industry diversification strategy.
What countries does BIS invest in?
BIS's geographic exposure is shown in the Countries tab under Portfolio Allocations. This reveals the fund's international diversification and exposure to different regions and global markets.
How diversified is BIS ETF?
BIS's diversification can be assessed by reviewing its 6 holdings, sector allocation, and geographic exposure. A well-diversified ETF spreads investments across multiple securities, sectors, and regions to reduce concentration risk.