| 1 | TAK | Takeda Pharmaceutical Company Limited | $16.82 | $53.92B | $27.78B | $1.18B | $0.37 | 3.23M |
| 2 | HLN | Haleon plc | $9.71 | $43.51B | $22.03B | $3.33B | $0.74 | 9.42M |
| 3 | TEVA | Teva Pharmaceutical Industries Limited | $31.18 | $36.76B | $17.35B | $1.56B | $1.34 | 5.29M |
| 4 | ZTS | Zoetis Inc. | $74.57 | $31.50B | $9.51B | $2.64B | $6.04 | 6.69M |
| 5 | UTHR | United Therapeutics Corporation | $529.53 | $24.99B | $3.17B | $1.29B | $27.00 | 504.01K |
| 6 | VTRS | Viatris Inc. | $17.28 | $20.31B | $14.56B | -$296.50M | $-0.25 | 9.84M |
| 7 | NBIX | Neurocrine Biosciences, Inc. | $174.15 | $18.01B | $3.10B | $668.60M | $6.51 | 1.16M |
| 8 | ELAN | Elanco Animal Health Incorporated | $24.78 | $12.54B | $4.89B | -$242.00M | $-0.48 | 4.68M |
| 9 | RDY | Dr. Reddy's Laboratories Limited | $11.80 | $9.83B | $3.50B | $444.81M | $0.61 | 2.89M |
| 10 | LQDA | Liquidia Corporation | $89.03 | $9.00B | $288.06M | $22.30M | $0.24 | 2.18M |
| 11 | ALKS | Alkermes plc | $52.97 | $8.80B | $1.56B | $152.72M | $0.91 | 2.32M |
| 12 | HIMS | Hims & Hers Health, Inc. | $32.74 | $7.48B | $2.37B | -$13.23M | $-0.05 | 15.77M |
| 13 | LNTH | Lantheus Holdings, Inc. | $103.73 | $6.82B | $1.55B | $279.03M | $4.13 | 921.66K |
| 14 | AMRX | Amneal Pharmaceuticals, Inc. | $17.97 | $5.91B | $3.05B | $122.36M | $0.38 | 2.28M |
| 15 | KNSA | Kiniksa Pharmaceuticals International, plc | $63.05 | $5.20B | $754.04M | $73.06M | $0.92 | 870.17K |
| 16 | RGC | Regencell Bioscience Holdings Limited | $5.62 | $2.78B | $0.00 | $25.31M | $0.06 | 458.72K |
| 17 | SUPN | Supernus Pharmaceuticals, Inc. | $47.19 | $2.72B | $776.83M | -$29.02M | $-0.51 | 836.39K |
| 18 | PBH | Prestige Consumer Healthcare Inc. | $48.94 | $2.33B | $1.09B | $190.30M | $3.91 | 648.86K |
| 19 | BCRX | BioCryst Pharmaceuticals, Inc. | $9.38 | $2.27B | $885.72M | -$457.98M | $-2.03 | 5.50M |
| 20 | AMLX | Amylyx Pharmaceuticals, Inc. | $17.59 | $1.94B | $0.00 | -$150.11M | $-1.55 | 1.68M |
| 21 | HCM | HUTCHMED (China) Limited | $10.96 | $1.91B | $602.20M | $466.88M | $2.67 | 50.27K |
| 22 | ANIP | ANI Pharmaceuticals, Inc. | $78.53 | $1.69B | $923.71M | $92.15M | $4.38 | 311.56K |
| 23 | TRLV | Trulieve Cannabis Corp. | $8.55 | $1.69B | $1.17B | -$81.80M | $-0.42 | 1.28M |
| 24 | BHC | Bausch Health Companies Inc. | $4.45 | $1.69B | $10.53B | -$1.21B | $-3.23 | 2.54M |
| 25 | HROW | Harrow, Inc. | $41.88 | $1.56B | $268.68M | -$14.96M | $-0.39 | 747.47K |
| 26 | XERS | Xeris Biopharma Holdings, Inc. | $8.41 | $1.49B | $314.85M | $12.01M | $0.07 | 2.18M |
| 27 | COLL | Collegium Pharmaceutical, Inc. | $35.59 | $1.43B | $796.33M | $74.95M | $1.89 | 440.04K |
| 28 | PRGO | Perrigo Company plc | $10.10 | $1.40B | $4.18B | -$1.82B | $-13.12 | 3.72M |
| 29 | PAHC | Phibro Animal Health Corporation | $34.04 | $1.40B | $1.50B | $95.23M | $2.33 | 281.11K |
| 30 | ETON | Eton Pharmaceuticals, Inc. | $44.14 | $1.39B | $86.93M | -$1.48M | $-0.05 | 476.31K |
| 31 | PCRX | Pacira BioSciences, Inc. | $25.93 | $1.06B | $734.86M | $5.14M | $0.12 | 500.62K |
| 32 | ALVO | Alvotech | $3.18 | $1.05B | $559.31M | -$80.77M | $-0.27 | 878.77K |
| 33 | CRON | Cronos Group Inc. | $2.74 | $1.05B | $159.48M | -$2.07M | $-0.01 | 870.36K |
| 34 | BIOA | BioAge Labs, Inc. | $21.90 | $930.32M | $10.32M | -$89.93M | $-2.39 | 666.73K |
| 35 | AMPH | Amphastar Pharmaceuticals, Inc. | $18.87 | $876.66M | $720.53M | $79.23M | $1.67 | 528.09K |
| 36 | ESPR | Esperion Therapeutics, Inc. | $3.18 | $799.30M | $418.24M | -$7.42M | $-0.03 | 14.14M |
| 37 | EVO | Evotec SE | $1.98 | $703.21M | $942.89M | -$157.19M | $-0.44 | 52.82K |
| 38 | IRWD | Ironwood Pharmaceuticals, Inc. | $3.79 | $631.76M | $361.51M | $102.18M | $0.58 | 2.45M |
| 39 | AQST | Aquestive Therapeutics, Inc. | $3.77 | $462.24M | $50.27M | -$68.91M | $-0.61 | 2.11M |
| 40 | TLRY | Tilray Brands, Inc. | $3.99 | $449.58M | $858.27M | -$1.34B | $-12.54 | 3.47M |
| 41 | EBS | Emergent BioSolutions Inc. | $7.50 | $423.75M | $656.40M | -$8.60M | $-0.16 | 893.23K |
| 42 | KMDA | Kamada Ltd. | $6.96 | $410.84M | $181.68M | $20.37M | $0.35 | 35.11K |
| 43 | EOLS | Evolus, Inc. | $5.99 | $390.47M | $301.79M | -$43.42M | $-0.67 | 776.74K |
| 44 | AKBA | Akebia Therapeutics, Inc. | $1.22 | $325.80M | $232.40M | -$20.51M | $-0.08 | 5.54M |
| 45 | CGC | Canopy Growth Corporation | $0.91 | $312.74M | $197.86M | -$232.11M | $-0.96 | 4.40M |
| 46 | ORGO | Organogenesis Holdings Inc. | $2.43 | $310.55M | $514.17M | -$10.14M | $-0.08 | 779.53K |
| 47 | TKNO | Alpha Teknova, Inc. | $5.20 | $278.75M | $41.80M | -$17.17M | $-0.32 | 196.49K |
| 48 | RMTI | Rockwell Medical, Inc. | $6.53 | $257.20M | $67.68M | -$5.40M | $-0.14 | 41.42K |
| 49 | SIGA | SIGA Technologies, Inc. | $3.15 | $225.70M | $93.78M | $20.26M | $0.28 | 602.81K |
| 50 | ANIK | Anika Therapeutics, Inc. | $14.67 | $198.50M | $116.26M | -$11.06M | $-0.77 | 72.72K |
| 51 | DERM | Journey Medical Corporation | $6.58 | $179.67M | $64.68M | -$9.59M | $-0.38 | 293.49K |
| 52 | LFCR | Lifecore Biomedical, Inc. | $4.43 | $166.02M | $129.82M | -$42.93M | $-1.15 | 206.59K |
| 53 | ACB | Aurora Cannabis Inc. | $2.69 | $152.56M | $226.31M | -$27.45M | $-0.48 | 1.27M |
| 54 | OGI | Organigram Global Inc. | $0.92 | $120.99M | $194.87M | -$17.92M | $-0.14 | 497.06K |
| 55 | CRDL | Cardiol Therapeutics Inc. | $1.23 | $107.00M | $0.00 | -$25.02M | $-0.26 | 645.94K |
| 56 | CPIX | Cumberland Pharmaceuticals Inc. | $6.99 | $104.50M | $41.94M | -$7.23M | $-0.48 | 91.73K |
| 57 | APUS | Apimeds Pharmaceuticals US, Inc. | $6.53 | $101.35M | $0.00 | -$40.09M | $-3.01 | 14.24K |
| 58 | ZYBT | Zhengye Biotechnology Holding Limited | $1.80 | $85.23M | $17.18M | -$10.30M | $-0.22 | 6.84M |
| 59 | TLPH | Talphera, Inc. | $1.37 | $58.10M | $1.00K | -$14.25M | $-0.31 | 400.31K |
| 60 | CTOR | Citius Oncology, Inc. | $0.58 | $57.84M | $5.61M | -$42.51M | $-0.50 | 56.01K |
| 61 | INCR | InterCure Ltd. | $0.95 | $51.22M | $79.35M | -$23.15M | $-0.46 | 68.12K |
| 62 | SXTC | China SXT Pharmaceuticals, Inc. | $0.33 | $38.59M | $1.74M | -$3.30M | $-2.32 | 2.93M |
| 63 | IXHL | Incannex Healthcare Inc. | $3.16 | $36.81M | $86.00K | -$48.50M | $-8.77 | 254.49K |
| 64 | SCYX | SCYNEXIS, Inc. | $3.96 | $25.22M | $20.34M | -$24.52M | $-0.88 | 81.94K |
| 65 | TXMD | TherapeuticsMD, Inc. | $2.06 | $23.98M | $3.35M | $179.00K | $0.02 | 42.14K |
| 66 | AYTU | Aytu BioPharma, Inc. | $2.16 | $22.71M | $56.60M | -$34.05M | $-2.91 | 22.59K |
| 67 | CABR | Caring Brands, Inc. | $1.40 | $18.99M | $4.22K | -$6.28M | $-0.47 | 70.31K |
| 68 | OPTH | Optimi Health Corp. | $4.75 | $15.30M | $164.79K | -$3.84M | $-1.19 | 123.33K |
| 69 | BFRI | Biofrontera Inc. | $1.09 | $12.73M | $43.20M | -$11.09M | $-1.02 | 321.48K |
| 70 | BTAI | BioXcel Therapeutics, Inc. | $0.87 | $10.62M | $680.00K | -$75.33M | $-6.49 | 1.21M |
| 71 | BGM | BGM Group Ltd. | $0.29 | $9.19M | $34.00M | -$3.15M | $-0.16 | 558.73K |
| 72 | CPHI | China Pharma Holdings, Inc. | $1.85 | $7.94M | $3.99M | -$3.55M | $-0.90 | 7.25M |
| 73 | INM | InMed Pharmaceuticals Inc. | $1.85 | $7.49M | $3.55M | -$9.26M | $-3.90 | 1.79M |
| 74 | GELS | Gelteq Limited | $0.73 | $6.81M | $103.08K | -$2.83M | $-0.30 | 7.56M |
| 75 | YCBD | cbdMD, Inc. | $0.58 | $6.02M | $19.98M | -$2.66M | $-0.31 | 191.65K |
| 76 | RDHL | RedHill Biopharma Ltd. | $0.67 | $2.11M | $9.55M | -$9.31M | $-4.25 | 150.05K |
| 77 | SNOA | Sonoma Pharmaceuticals, Inc. | $1.16 | $1.95M | $17.72M | -$3.37M | $-2.04 | 133.40K |
| 78 | SHPH | Shuttle Pharmaceuticals Holdings, Inc. | $2.99 | $1.50M | $0.00 | -$10.82M | $-6.53 | 3.49M |
| 79 | SBFM | Sunshine Biopharma, Inc. | $1.71 | $838.92K | $35.49M | -$6.04M | $-2.43 | 94.86K |
| 80 | PRFX | PRF Technologies Ltd. | $1.15 | $745.17K | $0.00 | -$4.09M | $-14.88 | 2.36M |
| 81 | AKAN | Akanda Corp. | $8.07 | $551.33K | $1.09M | -$49.67M | $-1,386.19 | 216.30K |
| 82 | UPC | Universe Pharmaceuticals INC | $3.79 | $13.18K | $40.88M | -$12.40M | $-64.64 | 2.32M |
| 83 | IMCC | IM Cannabis Corp. | $0.13 | $789.15 | $31.36M | -$7.89M | $-2.55 | 7.81M |
