| 1 | TAK | Takeda Pharmaceutical Company Limited | $16.58 | $53.11B | $28.21B | $721.95M | $0.23 | 3.08M |
| 2 | TEVA | Teva Pharmaceutical Industries Limited | $34.07 | $40.12B | $17.35B | $1.56B | $1.34 | 6.48M |
| 3 | ZTS | Zoetis Inc. | $78.92 | $34.09B | $9.47B | $2.67B | $6.02 | 6.59M |
| 4 | UTHR | United Therapeutics Corporation | $566.80 | $27.16B | $3.18B | $1.33B | $27.79 | 441.18K |
| 5 | VTRS | Viatris Inc. | $16.17 | $19.02B | $14.30B | -$3.51B | $-3.00 | 11.87M |
| 6 | NBIX | Neurocrine Biosciences, Inc. | $154.36 | $16.11B | $2.86B | $478.60M | $4.67 | 1.25M |
| 7 | RGC | Regencell Bioscience Holdings Limited | $27.00 | $13.74B | $0.00 | $25.31M | $0.09 | 105.39K |
| 8 | RDY | Dr. Reddy's Laboratories Limited | $13.45 | $11.33B | $3.59B | $587.35M | $0.81 | 2.94M |
| 9 | LQDA | Liquidia Corporation | $59.98 | $4.90B | $158.32M | -$68.92M | $-0.77 | 1.43M |
| 10 | INDV | Indivior PLC | $36.99 | $4.71B | $1.29B | $252.00M | $1.98 | 2.07M |
| 11 | KNSA | Kiniksa Pharmaceuticals International, plc | $53.34 | $4.42B | $754.04M | $73.06M | $0.92 | 774.36K |
| 12 | SUPN | Supernus Pharmaceuticals, Inc. | $47.62 | $2.73B | $718.95M | -$38.55M | $-0.68 | 678.37K |
| 13 | PBH | Prestige Consumer Healthcare Inc. | $46.44 | $2.24B | $1.10B | $186.50M | $3.78 | 661.45K |
| 14 | AVDL | Avadel Pharmaceuticals plc | $21.64 | $2.19B | $248.52M | -$278.00K | $0.00 | 0.00 |
| 15 | DVAX | Dynavax Technologies Corporation | $15.50 | $2.12B | $330.51M | -$43.40M | $-0.31 | 0.00 |
| 16 | ANIP | ANI Pharmaceuticals, Inc. | $80.32 | $1.68B | $883.37M | $78.34M | $3.79 | 373.02K |
| 17 | PRGO | Perrigo Company plc | $10.61 | $1.48B | $4.25B | -$1.43B | $-10.30 | 2.50M |
| 18 | PAHC | Phibro Animal Health Corporation | $33.90 | $1.40B | $1.46B | $92.09M | $2.26 | 386.01K |
| 19 | AMLX | Amylyx Pharmaceuticals, Inc. | $12.74 | $1.22B | $0.00 | -$144.74M | $-1.60 | 1.12M |
| 20 | HROW | Harrow, Inc. | $30.68 | $1.14B | $272.30M | -$5.14M | $-0.14 | 791.37K |
| 21 | ETON | Eton Pharmaceuticals, Inc. | $32.89 | $1.02B | $79.95M | -$4.60M | $-0.16 | 393.71K |
| 22 | ALVO | Alvotech | $3.28 | $946.86M | $586.21M | $27.89M | $0.09 | 403.41K |
| 23 | BIOA | BioAge Labs, Inc. | $16.37 | $551.21M | $8.99M | -$80.61M | $-2.25 | 391.77K |
| 24 | AQST | Aquestive Therapeutics, Inc. | $4.09 | $504.33M | $44.55M | -$83.78M | $-0.78 | 1.53M |
| 25 | KMDA | Kamada Ltd. | $7.60 | $451.86M | $180.46M | $20.20M | $0.35 | 46.24K |
| 26 | CGC | Canopy Growth Corporation | $0.99 | $339.42M | $202.48M | -$237.53M | $-0.99 | 12.97M |
| 27 | SIGA | SIGA Technologies, Inc. | $4.37 | $305.75M | $94.58M | $23.31M | $0.33 | 549.95K |
| 28 | TKNO | Alpha Teknova, Inc. | $3.72 | $193.83M | $40.52M | -$17.26M | $-0.32 | 111.58K |
| 29 | ACB | Aurora Cannabis Inc. | $3.30 | $188.02M | $269.80M | -$4.07M | $-0.07 | 1.27M |
| 30 | SXTC | China SXT Pharmaceuticals, Inc. | $1.55 | $182.16M | $1.74M | -$3.30M | $-2.32 | 31.76K |
| 31 | LFCR | Lifecore Biomedical, Inc. | $4.38 | $164.12M | $137.74M | -$37.94M | $-1.01 | 257.42K |
| 32 | DERM | Journey Medical Corporation | $6.15 | $153.11M | $61.86M | -$11.43M | $-0.48 | 232.23K |
| 33 | ASRT | Assertio Holdings, Inc. | $23.41 | $149.71M | $118.71M | -$30.38M | $-4.62 | 422.63K |
| 34 | OGI | Organigram Global Inc. | $1.04 | $144.30M | $203.64M | $13.21M | $0.10 | 887.44K |
| 35 | CPIX | Cumberland Pharmaceuticals Inc. | $5.41 | $76.58M | $44.52M | -$2.84M | $-0.19 | 1.95M |
| 36 | CTOR | Citius Oncology, Inc. | $0.83 | $72.51M | $3.94M | -$23.64M | $-0.31 | 122.11K |
| 37 | TLPH | Talphera, Inc. | $0.83 | $53.38M | $28.00K | -$14.29M | $-0.34 | 149.05K |
| 38 | IXHL | Incannex Healthcare Inc. | $3.70 | $44.15M | $86.00K | -$48.50M | $-8.52 | 426.75K |
| 39 | INCR | InterCure Ltd. | $0.85 | $44.07M | $83.74M | -$24.43M | $-0.48 | 36.03K |
| 40 | ZYBT | Zhengye Biotechnology Holding Limited | $0.87 | $43.70M | $17.11M | -$10.26M | $-0.22 | 56.04K |
| 41 | RMTI | Rockwell Medical, Inc. | $0.80 | $30.79M | $69.26M | -$5.31M | $-0.15 | 232.80K |
| 42 | TXMD | TherapeuticsMD, Inc. | $2.04 | $23.37M | $3.02M | -$569.00K | $-0.05 | 22.24K |
| 43 | AYTU | Aytu BioPharma, Inc. | $2.08 | $21.08M | $62.64M | -$24.44M | $-2.20 | 45.00K |
| 44 | APUS | Apimeds Pharmaceuticals US, Inc. | $1.42 | $18.79M | $0.00 | -$7.69M | $-0.79 | 241.81K |
| 45 | BTAI | BioXcel Therapeutics, Inc. | $1.08 | $13.80M | $642.00K | -$69.90M | $-7.15 | 844.49K |
| 46 | CABR | Caring Brands, Inc. | $0.92 | $11.94M | $4.22K | -$6.28M | $-0.47 | 70.04K |
| 47 | BFRI | Biofrontera Inc. | $0.81 | $9.25M | $41.71M | -$10.54M | $-1.04 | 215.36K |
| 48 | BGM | BGM Group Ltd. | $0.28 | $8.69M | $34.00M | -$3.15M | $-0.16 | 273.84K |
| 49 | YCBD | cbdMD, Inc. | $0.75 | $6.93M | $19.09M | -$2.34M | $-0.38 | 2.61M |
| 50 | GELS | Gelteq Limited | $0.39 | $3.76M | $105.19K | -$2.88M | $-0.31 | 128.00K |
| 51 | CPHI | China Pharma Holdings, Inc. | $0.72 | $3.19M | $4.14M | -$3.19M | $-0.81 | 521.86K |
| 52 | RDHL | RedHill Biopharma Ltd. | $0.93 | $2.95M | $9.55M | -$9.31M | $-4.25 | 81.82K |
| 53 | SBFM | Sunshine Biopharma, Inc. | $0.44 | $2.12M | $36.31M | -$5.98M | $-1.50 | 14.33M |
| 54 | SNOA | Sonoma Pharmaceuticals, Inc. | $1.01 | $1.76M | $17.72M | -$3.37M | $-2.04 | 319.05K |
| 55 | SHPH | Shuttle Pharmaceuticals Holdings, Inc. | $0.61 | $1.02M | $0.00 | -$11.72M | $-8.68 | 1.65M |
| 56 | PRFX | PRF Technologies Ltd. | $1.51 | $991.40K | $0.00 | -$4.09M | $-14.88 | 78.72K |
| 57 | IMCC | IM Cannabis Corp. | $0.22 | $958.09K | $39.81M | -$8.31M | $-2.15 | 590.69K |
| 58 | AKAN | Akanda Corp. | $13.58 | $565.51K | $1.60M | -$31.31M | $-1,669.37 | 4.49M |
| 59 | UPC | Universe Pharmaceuticals INC | $2.54 | $8.97K | $40.88M | -$12.40M | $-64.64 | 12.07K |
| 60 | INM | InMed Pharmaceuticals Inc. | $1.60 | $2.69K | $4.81M | -$8.42M | $-5.14 | 27.77K |
