| 1 | TAK | Takeda Pharmaceutical Company Limited | $18.74 | $60.06B | $27.96B | $707.27M | $0.22 | 2.64M |
| 2 | ZTS | Zoetis Inc. | $117.94 | $51.73B | $9.47B | $2.67B | $6.09 | 2.18M |
| 3 | HLN | Haleon plc | $9.93 | $44.50B | $21.82B | $3.14B | $0.70 | 4.75M |
| 4 | TEVA | Teva Pharmaceutical Industries Limited | $30.08 | $34.98B | $17.26B | $1.41B | $1.20 | 2.84M |
| 5 | UTHR | United Therapeutics Corporation | $564.81 | $27.05B | $3.18B | $1.33B | $27.86 | 801.73K |
| 6 | VTRS | Viatris Inc. | $13.44 | $15.49B | $14.30B | -$3.51B | $-3.05 | 5.84M |
| 7 | RGC | Regencell Bioscience Holdings Limited | $30.80 | $15.23B | $0.00 | $25.31M | $0.05 | 327.69K |
| 8 | NBIX | Neurocrine Biosciences, Inc. | $131.60 | $13.49B | $2.86B | $478.60M | $4.67 | 704.43K |
| 9 | ELAN | Elanco Animal Health Incorporated | $23.08 | $11.46B | $4.71B | -$232.00M | $-0.47 | 4.25M |
| 10 | RDY | Dr. Reddy's Laboratories Limited | $13.32 | $11.10B | $3.73B | $609.97M | $0.73 | 4.18M |
| 11 | ALKS | Alkermes plc | $34.84 | $5.88B | $1.48B | $241.66M | $1.43 | 2.49M |
| 12 | LNTH | Lantheus Holdings, Inc. | $76.10 | $5.21B | $1.54B | $233.56M | $3.52 | 422.48K |
| 13 | HIMS | Hims & Hers Health, Inc. | $19.14 | $4.94B | $2.35B | $128.37M | $0.52 | 23.33M |
| 14 | AMRX | Amneal Pharmaceuticals, Inc. | $12.48 | $4.05B | $3.02B | $72.06M | $0.22 | 1.35M |
| 15 | INDV | Indivior PLC | $30.47 | $3.90B | $1.24B | $210.00M | $1.64 | 2.15M |
| 16 | KNSA | Kiniksa Pharmaceuticals International, plc | $48.82 | $3.86B | $677.56M | $59.01M | $0.75 | 435.52K |
| 17 | SUPN | Supernus Pharmaceuticals, Inc. | $50.48 | $2.85B | $718.95M | -$38.55M | $-0.67 | 472.50K |
| 18 | HCM | HUTCHMED (China) Limited | $15.42 | $2.69B | $602.20M | $466.88M | $2.68 | 36.06K |
| 19 | PBH | Prestige Consumer Healthcare Inc. | $52.48 | $2.52B | $1.10B | $186.50M | $3.88 | 1.59M |
| 20 | PAHC | Phibro Animal Health Corporation | $55.52 | $2.27B | $1.46B | $92.09M | $2.25 | 246.52K |
| 21 | AVDL | Avadel Pharmaceuticals plc | $21.64 | $2.19B | $248.52M | -$278.00K | $0.00 | 0.00 |
| 22 | DVAX | Dynavax Technologies Corporation | $15.50 | $2.12B | $330.51M | -$43.40M | $-0.32 | 0.00 |
| 23 | BHC | Bausch Health Companies Inc. | $5.35 | $2.01B | $10.31B | $155.28M | $0.42 | 1.61M |
| 24 | BCRX | BioCryst Pharmaceuticals, Inc. | $9.02 | $1.98B | $874.84M | $263.86M | $1.20 | 7.82M |
| 25 | ANIP | ANI Pharmaceuticals, Inc. | $74.21 | $1.58B | $883.37M | $78.34M | $3.69 | 275.75K |
| 26 | PRGO | Perrigo Company plc | $10.85 | $1.50B | $4.25B | -$1.43B | $-10.29 | 3.15M |
| 27 | AMLX | Amylyx Pharmaceuticals, Inc. | $14.95 | $1.41B | $0.00 | -$144.74M | $-1.53 | 1.28M |
| 28 | HROW | Harrow, Inc. | $35.31 | $1.30B | $272.30M | -$5.14M | $-0.14 | 343.92K |
| 29 | COLL | Collegium Pharmaceutical, Inc. | $32.31 | $1.28B | $780.57M | $62.87M | $1.58 | 583.69K |
| 30 | ALVO | Alvotech | $3.65 | $1.10B | $570.95M | $69.50M | $0.23 | 246.83K |
| 31 | PCRX | Pacira BioSciences, Inc. | $22.70 | $1.02B | $726.41M | $7.03M | $0.16 | 750.44K |
| 32 | IXHL | Incannex Healthcare Inc. | $2.90 | $1.01B | $78.62K | -$52.47M | $-0.15 | 391.82K |
| 33 | AMPH | Amphastar Pharmaceuticals, Inc. | $20.45 | $986.00M | $719.89M | $98.09M | $2.08 | 390.45K |
| 34 | CRON | Cronos Group Inc. | $2.53 | $967.80M | $147.27M | -$9.47M | $-0.02 | 639.47K |
| 35 | EVO | Evotec SE | $2.59 | $920.33M | $871.38M | -$183.16M | $-0.52 | 88.69K |
| 36 | TLRY | Tilray Brands, Inc. | $6.55 | $722.75M | $837.32M | -$2.11B | $-19.10 | 5.51M |
| 37 | ETON | Eton Pharmaceuticals, Inc. | $24.99 | $672.06M | $70.32M | -$6.68M | $-0.25 | 472.29K |
| 38 | IRWD | Ironwood Pharmaceuticals, Inc. | $3.54 | $629.28M | $296.15M | $24.02M | $0.14 | 1.89M |
| 39 | BIOA | BioAge Labs, Inc. | $17.50 | $627.38M | $5.92M | -$75.79M | $-2.11 | 301.36K |
| 40 | ESPR | Esperion Therapeutics, Inc. | $2.61 | $542.53M | $403.13M | -$22.68M | $-0.08 | 5.84M |
| 41 | AQST | Aquestive Therapeutics, Inc. | $4.13 | $503.72M | $44.55M | -$83.78M | $-0.69 | 901.24K |
| 42 | KMDA | Kamada Ltd. | $8.47 | $498.41M | $174.79M | $20.44M | $0.35 | 32.24K |
| 43 | EBS | Emergent BioSolutions Inc. | $8.23 | $466.64M | $710.10M | $52.60M | $0.93 | 880.37K |
| 44 | SIGA | SIGA Technologies, Inc. | $5.24 | $375.21M | $94.58M | $23.31M | $0.33 | 872.38K |
| 45 | AKBA | Akebia Therapeutics, Inc. | $1.38 | $366.21M | $236.19M | -$5.34M | $-0.02 | 1.88M |
| 46 | CGC | Canopy Growth Corporation | $1.00 | $345.53M | $199.70M | -$234.27M | $-0.68 | 6.78M |
| 47 | ORGO | Organogenesis Holdings Inc. | $2.24 | $291.76M | $563.57M | $37.03M | $0.28 | 505.02K |
| 48 | EOLS | Evolus, Inc. | $4.03 | $259.81M | $297.18M | -$51.64M | $-0.80 | 837.68K |
| 49 | ANIK | Anika Therapeutics, Inc. | $14.80 | $217.10M | $112.82M | -$10.88M | $-0.74 | 98.85K |
| 50 | ACB | Aurora Cannabis Inc. | $3.44 | $197.20M | $267.65M | -$64.14M | $-1.12 | 687.50K |
| 51 | OGI | Organigram Global Inc. | $1.38 | $188.75M | $200.85M | $13.03M | $0.10 | 585.17K |
| 52 | TKNO | Alpha Teknova, Inc. | $3.16 | $169.01M | $40.52M | -$17.26M | $-0.32 | 68.17K |
| 53 | LFCR | Lifecore Biomedical, Inc. | $3.84 | $143.63M | $133.82M | -$35.90M | $-0.96 | 602.46K |
| 54 | ASRT | Assertio Holdings, Inc. | $19.21 | $136.41M | $137.35M | -$28.92M | $-4.07 | 126.26K |
| 55 | DERM | Journey Medical Corporation | $4.95 | $123.55M | $59.40M | -$8.66M | $-0.35 | 325.81K |
| 56 | CRDL | Cardiol Therapeutics Inc. | $1.41 | $119.47M | $0.00 | -$24.95M | $-0.29 | 1.11M |
| 57 | CTOR | Citius Oncology, Inc. | $0.70 | $61.49M | $3.94M | -$23.64M | $-0.27 | 433.50K |
| 58 | ZYBT | Zhengye Biotechnology Holding Limited | $0.88 | $47.64M | $27.07M | $1.64M | $0.03 | 17.77K |
| 59 | CPIX | Cumberland Pharmaceuticals Inc. | $3.17 | $47.41M | $44.52M | -$2.84M | $-0.19 | 80.98K |
| 60 | SCYX | SCYNEXIS, Inc. | $0.89 | $44.34M | $20.60M | -$8.61M | $-0.20 | 258.56K |
| 61 | INCR | InterCure Ltd. | $0.76 | $43.17M | $77.67M | -$22.66M | $-0.40 | 4.63K |
| 62 | RMTI | Rockwell Medical, Inc. | $0.96 | $34.47M | $75.58M | -$5.52M | $-0.15 | 125.53K |
| 63 | TLPH | Talphera, Inc. | $0.72 | $29.94M | $28.00K | -$12.39M | $-0.30 | 172.86K |
| 64 | AYTU | Aytu BioPharma, Inc. | $2.68 | $26.90M | $62.64M | -$24.44M | $-2.44 | 55.34K |
| 65 | APUS | Apimeds Pharmaceuticals US, Inc. | $1.88 | $23.64M | $0.00 | -$5.16M | $-0.41 | 31.59K |
| 66 | TXMD | TherapeuticsMD, Inc. | $2.00 | $23.15M | $2.80M | $302.00K | $0.03 | 16.09K |
| 67 | BTAI | BioXcel Therapeutics, Inc. | $1.18 | $16.75M | $752.00K | -$68.21M | $-4.80 | 1.01M |
| 68 | CABR | Caring Brands, Inc. | $1.11 | $14.91M | $465.00 | -$1.52M | $-0.15 | 39.19K |
| 69 | BGM | BGM Group Ltd. | $0.34 | $10.65M | $25.10M | -$1.44M | $-0.20 | 316.73K |
| 70 | BFRI | Biofrontera Inc. | $0.98 | $10.56M | $37.16M | -$17.57M | $-1.63 | 129.64K |
| 71 | GELS | Gelteq Limited | $0.68 | $9.64M | $101.71K | -$2.79M | $-0.72 | 10.44K |
| 72 | YCBD | cbdMD, Inc. | $0.73 | $6.60M | $19.09M | -$2.34M | $-0.26 | 588.26K |
| 73 | SBFM | Sunshine Biopharma, Inc. | $1.04 | $4.74M | $37.32M | -$5.99M | $-1.32 | 24.86K |
| 74 | SNOA | Sonoma Pharmaceuticals, Inc. | $2.37 | $4.06M | $17.72M | -$3.37M | $-1.97 | 9.46K |
| 75 | CPHI | China Pharma Holdings, Inc. | $0.63 | $2.44M | $4.05M | -$3.19M | $-0.82 | 27.45K |
| 76 | SHPH | Shuttle Pharmaceuticals Holdings, Inc. | $0.76 | $1.70M | $0.00 | -$10.71M | $-4.79 | 199.63K |
| 77 | IMCC | IM Cannabis Corp. | $0.34 | $1.65M | $37.58M | -$3.44M | $-0.71 | 174.66K |
| 78 | RDHL | RedHill Biopharma Ltd. | $0.80 | $1.44M | $9.55M | -$9.31M | $-5.17 | 12.91K |
| 79 | AKAN | Akanda Corp. | $0.69 | $477.47K | $1.60M | -$31.31M | $-45.12 | 88.89K |
| 80 | PRFX | PRF Technologies Ltd. | $2.10 | $178.38K | $0.00 | -$4.09M | $-48.10 | 6.53K |
| 81 | SXTC | China SXT Pharmaceuticals, Inc. | $1.89 | $17.93K | $1.74M | -$3.30M | $-1.35 | 67.46K |
| 82 | UPC | Universe Pharmaceuticals INC | $3.16 | $10.99K | $40.88M | -$12.40M | $-22.01 | 9.28K |
| 83 | INM | InMed Pharmaceuticals Inc. | $0.68 | $2.68K | $4.81M | -$8.42M | $-2,129.27 | 23.34K |
