| 1 | TAK | Takeda Pharmaceutical Company Limited | $17.45 | $55.14B | $29.15B | $1.15B | $0.36 | 3.88M |
| 2 | HLN | Haleon plc | $10.03 | $44.73B | $22.30B | $3.37B | $0.75 | 9.84M |
| 3 | TEVA | Teva Pharmaceutical Industries Limited | $35.36 | $41.19B | $17.31B | $703.00M | $0.60 | 5.25M |
| 4 | ZTS | Zoetis Inc. | $72.66 | $30.69B | $9.51B | $2.64B | $6.04 | 6.60M |
| 5 | UTHR | United Therapeutics Corporation | $538.84 | $25.43B | $3.17B | $1.29B | $27.00 | 465.57K |
| 6 | VTRS | Viatris Inc. | $16.41 | $19.29B | $14.56B | -$296.50M | $-0.25 | 10.14M |
| 7 | NBIX | Neurocrine Biosciences, Inc. | $163.41 | $17.03B | $3.37B | $705.50M | $6.82 | 1.28M |
| 8 | ELAN | Elanco Animal Health Incorporated | $22.12 | $11.19B | $4.89B | -$242.00M | $-0.48 | 6.58M |
| 9 | RDY | Dr. Reddy's Laboratories Limited | $12.22 | $10.19B | $3.49B | $337.91M | $0.41 | 3.01M |
| 10 | LQDA | Liquidia Corporation | $90.22 | $9.12B | $288.06M | $22.30M | $0.24 | 1.38M |
| 11 | ALKS | Alkermes plc | $49.17 | $8.53B | $1.67B | $66.12M | $0.39 | 1.80M |
| 12 | HIMS | Hims & Hers Health, Inc. | $31.59 | $7.21B | $2.37B | -$13.23M | $-0.05 | 14.04M |
| 13 | LNTH | Lantheus Holdings, Inc. | $100.95 | $6.64B | $1.55B | $279.03M | $4.13 | 1.44M |
| 14 | KNSA | Kiniksa Pharmaceuticals International, plc | $76.06 | $6.34B | $840.85M | $80.66M | $1.00 | 762.72K |
| 15 | AMRX | Amneal Pharmaceuticals, Inc. | $18.14 | $5.95B | $3.12B | $157.60M | $0.48 | 1.85M |
| 16 | SUPN | Supernus Pharmaceuticals, Inc. | $47.64 | $2.75B | $776.83M | -$29.02M | $-0.51 | 1.02M |
| 17 | RGC | Regencell Bioscience Holdings Limited | $5.41 | $2.68B | $0.00 | $25.31M | $0.06 | 436.62K |
| 18 | PBH | Prestige Consumer Healthcare Inc. | $54.85 | $2.62B | $1.09B | $190.30M | $3.91 | 546.55K |
| 19 | AMLX | Amylyx Pharmaceuticals, Inc. | $22.82 | $2.52B | $0.00 | -$150.11M | $-1.55 | 1.88M |
| 20 | BHC | Bausch Health Companies Inc. | $6.25 | $2.36B | $10.85B | -$1.10B | $-2.92 | 4.26M |
| 21 | BCRX | BioCryst Pharmaceuticals, Inc. | $9.38 | $2.27B | $885.72M | -$457.98M | $-2.03 | 4.14M |
| 22 | HCM | HUTCHMED (China) Limited | $12.51 | $2.18B | $602.20M | $466.88M | $2.67 | 50.63K |
| 23 | PRGO | Perrigo Company plc | $12.84 | $1.78B | $4.18B | -$1.82B | $-13.12 | 3.22M |
| 24 | TRLV | Trulieve Cannabis Corp. | $8.75 | $1.73B | $1.17B | -$81.80M | $-0.42 | 898.25K |
| 25 | ANIP | ANI Pharmaceuticals, Inc. | $78.25 | $1.69B | $923.71M | $89.67M | $4.26 | 329.33K |
| 26 | HROW | Harrow, Inc. | $40.44 | $1.51B | $268.68M | -$14.96M | $-0.39 | 548.82K |
| 27 | XERS | Xeris Biopharma Holdings, Inc. | $7.93 | $1.41B | $314.85M | $12.01M | $0.07 | 1.93M |
| 28 | PAHC | Phibro Animal Health Corporation | $34.29 | $1.41B | $1.50B | $95.23M | $2.33 | 256.82K |
| 29 | ETON | Eton Pharmaceuticals, Inc. | $44.60 | $1.41B | $86.93M | -$1.48M | $-0.05 | 509.51K |
| 30 | CRON | Cronos Group Inc. | $3.10 | $1.18B | $159.48M | -$2.07M | $-0.01 | 1.13M |
| 31 | COLL | Collegium Pharmaceutical, Inc. | $29.47 | $1.18B | $796.33M | $74.95M | $1.89 | 480.04K |
| 32 | ALVO | Alvotech | $3.81 | $1.12B | $559.17M | -$80.77M | $-0.28 | 760.32K |
| 33 | PCRX | Pacira BioSciences, Inc. | $25.02 | $1.02B | $734.86M | $5.14M | $0.12 | 606.62K |
| 34 | AMPH | Amphastar Pharmaceuticals, Inc. | $20.78 | $965.40M | $720.53M | $79.23M | $1.67 | 455.27K |
| 35 | ESPR | Esperion Therapeutics, Inc. | $3.18 | $799.30M | $418.24M | -$7.42M | $-0.03 | 14.94M |
| 36 | IRWD | Ironwood Pharmaceuticals, Inc. | $4.32 | $720.10M | $361.51M | $102.18M | $0.58 | 2.42M |
| 37 | EVO | Evotec SE | $2.00 | $710.31M | $954.33M | -$159.10M | $-0.45 | 72.30K |
| 38 | TLRY | Tilray Brands, Inc. | $4.57 | $511.07M | $915.45M | -$119.88M | $-1.08 | 4.53M |
| 39 | BIOA | BioAge Labs, Inc. | $11.72 | $497.87M | $10.32M | -$89.93M | $-2.39 | 1.10M |
| 40 | EOLS | Evolus, Inc. | $7.59 | $494.77M | $301.79M | -$43.42M | $-0.67 | 850.90K |
| 41 | AQST | Aquestive Therapeutics, Inc. | $3.94 | $483.08M | $50.27M | -$68.91M | $-0.61 | 2.06M |
| 42 | KMDA | Kamada Ltd. | $7.27 | $429.14M | $136.97M | $13.00M | $0.29 | 40.42K |
| 43 | CGC | Canopy Growth Corporation | $0.97 | $373.48M | $204.23M | -$188.67M | $-0.63 | 3.14M |
| 44 | TKNO | Alpha Teknova, Inc. | $6.46 | $346.30M | $41.80M | -$17.17M | $-0.32 | 135.02K |
| 45 | ANIK | Anika Therapeutics, Inc. | $21.42 | $293.82M | $120.65M | -$3.78M | $-0.27 | 92.43K |
| 46 | RMTI | Rockwell Medical, Inc. | $7.14 | $281.45M | $67.68M | -$5.40M | $-0.26 | 41.17K |
| 47 | EBS | Emergent BioSolutions Inc. | $4.84 | $273.46M | $661.30M | -$8.60M | $-0.16 | 974.53K |
| 48 | AKBA | Akebia Therapeutics, Inc. | $0.91 | $242.99M | $232.40M | -$20.51M | $-0.08 | 4.24M |
| 49 | ORGO | Organogenesis Holdings Inc. | $1.86 | $237.70M | $514.17M | -$10.14M | $-0.08 | 851.50K |
| 50 | SIGA | SIGA Technologies, Inc. | $3.05 | $218.53M | $93.78M | $20.26M | $0.28 | 776.04K |
| 51 | LFCR | Lifecore Biomedical, Inc. | $5.01 | $187.76M | $121.91M | -$48.88M | $-1.30 | 169.55K |
| 52 | DERM | Journey Medical Corporation | $6.43 | $175.57M | $64.68M | -$9.59M | $-0.38 | 178.84K |
| 53 | ACB | Aurora Cannabis Inc. | $2.99 | $169.57M | $228.51M | -$27.71M | $-0.49 | 1.22M |
| 54 | OGI | Organigram Global Inc. | $0.99 | $130.26M | $196.76M | -$18.09M | $-0.14 | 347.15K |
| 55 | CRDL | Cardiol Therapeutics Inc. | $1.42 | $123.52M | $0.00 | -$25.27M | $-0.26 | 887.41K |
| 56 | CPIX | Cumberland Pharmaceuticals Inc. | $7.80 | $116.69M | $41.94M | -$7.23M | $-0.48 | 121.22K |
| 57 | ZYBT | Zhengye Biotechnology Holding Limited | $1.89 | $89.49M | $17.25M | -$10.35M | $-0.22 | 10.78M |
| 58 | CTOR | Citius Oncology, Inc. | $0.75 | $75.32M | $5.61M | -$42.51M | $-0.50 | 92.86K |
| 59 | TLPH | Talphera, Inc. | $1.43 | $60.65M | $1.00K | -$14.25M | $-0.31 | 354.78K |
| 60 | INCR | InterCure Ltd. | $0.98 | $52.67M | $81.04M | -$23.64M | $-0.47 | 20.06K |
| 61 | IXHL | Incannex Healthcare Inc. | $3.16 | $38.96M | $86.00K | -$48.41M | $-5.62 | 165.95K |
| 62 | BGM | BGM Group Ltd. | $0.30 | $34.02M | $34.00M | -$3.15M | $-0.16 | 282.17K |
| 63 | SCYX | SCYNEXIS, Inc. | $5.24 | $33.38M | $20.34M | -$24.52M | $-4.04 | 198.87K |
| 64 | AYTU | Aytu BioPharma, Inc. | $2.36 | $24.81M | $56.60M | -$34.05M | $-2.91 | 26.89K |
| 65 | TXMD | TherapeuticsMD, Inc. | $2.07 | $24.09M | $3.35M | $179.00K | $0.02 | 23.59K |
| 66 | BTAI | BioXcel Therapeutics, Inc. | $0.90 | $21.25M | $680.00K | -$75.33M | $-5.21 | 1.15M |
| 67 | CABR | Caring Brands, Inc. | $1.34 | $19.29M | $4.16K | -$9.53M | $-0.69 | 85.45K |
| 68 | OPTH | Optimi Health Corp. | $5.05 | $16.26M | $-20.49K | -$4.19M | $-1.30 | 59.72K |
| 69 | BFRI | Biofrontera Inc. | $1.27 | $14.84M | $43.20M | -$11.09M | $-1.02 | 386.83K |
| 70 | APUS | Apimeds Pharmaceuticals US, Inc. | $4.23 | $6.56M | $0.00 | -$40.09M | $-9.63 | 30.82K |
| 71 | SBFM | Sunshine Biopharma, Inc. | $1.23 | $6.03M | $35.49M | -$6.04M | $-4.17 | 566.91K |
| 72 | INM | InMed Pharmaceuticals Inc. | $1.47 | $5.95M | $3.55M | -$9.26M | $-3.90 | 1.85M |
| 73 | YCBD | cbdMD, Inc. | $0.57 | $5.90M | $19.98M | -$2.66M | $-0.31 | 225.10K |
| 74 | GELS | Gelteq Limited | $0.56 | $5.85M | $104.04K | -$5.00M | $-0.49 | 100.84K |
| 75 | CPHI | China Pharma Holdings, Inc. | $1.13 | $4.85M | $3.99M | -$3.55M | $-0.90 | 7.61M |
| 76 | SNOA | Sonoma Pharmaceuticals, Inc. | $1.44 | $2.42M | $19.53M | -$3.17M | $-1.89 | 191.28K |
| 77 | SHPH | Shuttle Pharmaceuticals Holdings, Inc. | $4.36 | $2.19M | $0.00 | -$10.82M | $-38.78 | 2.97M |
| 78 | RDHL | RedHill Biopharma Ltd. | $0.61 | $1.91M | $9.55M | -$9.31M | $-4.25 | 61.39K |
| 79 | PRFX | PRF Technologies Ltd. | $1.04 | $673.89K | $0.00 | -$4.09M | $-14.88 | 173.93K |
| 80 | AKAN | Akanda Corp. | $5.13 | $350.48K | $1.09M | -$49.67M | $-1,386.19 | 237.62K |
| 81 | SXTC | China SXT Pharmaceuticals, Inc. | $0.05 | $30.92K | $1.74M | -$3.30M | $-2.32 | 995.35K |
| 82 | UPC | Universe Pharmaceuticals INC | $5.56 | $19.34K | $40.88M | -$12.40M | $-64.64 | 3.54M |
| 83 | IMCC | IM Cannabis Corp. | $0.12 | $739.35 | $31.66M | -$7.96M | $-2.57 | 3.07M |
