| 1 | TAK | Takeda Pharmaceutical Company Limited | $18.26 | $58.52B | $29.08B | $735.64M | $0.23 | 2.98M |
| 2 | ZTS | Zoetis Inc. | $125.56 | $55.73B | $9.40B | $2.65B | $5.98 | 3.75M |
| 3 | HLN | Haleon plc | $11.23 | $50.89B | $18.70B | $2.47B | $0.55 | 8.92M |
| 4 | TEVA | Teva Pharmaceutical Industries Limited | $34.41 | $40.02B | $17.26B | $1.41B | $1.20 | 10.00M |
| 5 | UTHR | United Therapeutics Corporation | $482.42 | $22.82B | $3.13B | $1.27B | $26.89 | 332.73K |
| 6 | VTRS | Viatris Inc. | $15.74 | $18.33B | $14.12B | -$3.69B | $-3.17 | 8.60M |
| 7 | RGC | Regencell Bioscience Holdings Limited | $31.57 | $15.61B | $0.00 | -$3.58M | $-0.01 | 90.42K |
| 8 | NBIX | Neurocrine Biosciences, Inc. | $127.76 | $13.10B | $2.68B | $428.00M | $4.18 | 1.61M |
| 9 | ELAN | Elanco Animal Health Incorporated | $24.86 | $12.35B | $4.59B | $36.00M | $0.07 | 3.42M |
| 10 | RDY | Dr. Reddy's Laboratories Limited | $14.40 | $12.00B | $3.87B | $583.65M | $0.70 | 1.39M |
| 11 | ALKS | Alkermes plc | $32.90 | $5.54B | $1.52B | $338.83M | $2.01 | 1.58M |
| 12 | AMRX | Amneal Pharmaceuticals, Inc. | $15.19 | $4.93B | $2.93B | $5.90M | $0.02 | 2.54M |
| 13 | LNTH | Lantheus Holdings, Inc. | $71.27 | $4.82B | $1.53B | $167.68M | $2.48 | 798.49K |
| 14 | INDV | Indivior PLC | $34.75 | $4.48B | $1.18B | $166.00M | $1.29 | 3.35M |
| 15 | HIMS | Hims & Hers Health, Inc. | $16.27 | $4.05B | $2.21B | $133.79M | $0.54 | 21.49M |
| 16 | KNSA | Kiniksa Pharmaceuticals International, plc | $45.38 | $3.63B | $597.97M | $35.92M | $0.45 | 524.27K |
| 17 | PBH | Prestige Consumer Healthcare Inc. | $66.27 | $3.32B | $1.08B | $178.58M | $3.71 | 362.21K |
| 18 | SUPN | Supernus Pharmaceuticals, Inc. | $51.62 | $2.92B | $681.54M | -$19.12M | $-0.34 | 720.98K |
| 19 | HCM | HUTCHMED (China) Limited | $14.87 | $2.60B | $630.20M | $37.73M | $0.22 | 24.47K |
| 20 | BHC | Bausch Health Companies Inc. | $5.99 | $2.23B | $10.03B | $362.00M | $0.97 | 1.96M |
| 21 | AVDL | Avadel Pharmaceuticals plc | $21.64 | $2.19B | $248.52M | -$278.00K | $0.00 | 0.00 |
| 22 | PAHC | Phibro Animal Health Corporation | $52.29 | $2.13B | $1.48B | $97.74M | $2.39 | 251.42K |
| 23 | DVAX | Dynavax Technologies Corporation | $15.50 | $2.12B | $330.51M | -$43.40M | $-0.32 | 0.00 |
| 24 | PRGO | Perrigo Company plc | $14.44 | $2.01B | $4.28B | -$51.80M | $-0.37 | 2.55M |
| 25 | HROW | Harrow, Inc. | $50.54 | $1.96B | $250.04M | -$4.99M | $-0.13 | 511.41K |
| 26 | COLL | Collegium Pharmaceutical, Inc. | $46.10 | $1.82B | $757.07M | $58.44M | $1.48 | 212.74K |
| 27 | ANIP | ANI Pharmaceuticals, Inc. | $78.90 | $1.66B | $826.88M | $38.09M | $1.81 | 220.09K |
| 28 | BCRX | BioCryst Pharmaceuticals, Inc. | $6.95 | $1.53B | $599.82M | -$8.78M | $-0.04 | 3.75M |
| 29 | ALVO | Alvotech | $4.64 | $1.39B | $571.16M | $69.53M | $0.23 | 530.84K |
| 30 | AMPH | Amphastar Pharmaceuticals, Inc. | $28.45 | $1.36B | $723.30M | $111.63M | $2.34 | 316.86K |
| 31 | EVO | Evotec SE | $3.53 | $1.25B | $895.64M | -$188.26M | $-0.53 | 404.60K |
| 32 | CRON | Cronos Group Inc. | $2.65 | $1.02B | $132.36M | $36.10M | $0.09 | 802.54K |
| 33 | PCRX | Pacira BioSciences, Inc. | $22.74 | $1.01B | $716.79M | $21.44M | $0.48 | 727.64K |
| 34 | IRWD | Ironwood Pharmaceuticals, Inc. | $4.78 | $849.71M | $338.99M | $28.55M | $0.16 | 2.08M |
| 35 | BIOA | BioAge Labs, Inc. | $19.63 | $703.74M | $0.00 | -$75.79M | $-2.11 | 391.97K |
| 36 | ESPR | Esperion Therapeutics, Inc. | $3.55 | $703.45M | $303.80M | -$105.83M | $-0.53 | 3.16M |
| 37 | TLRY | Tilray Brands, Inc. | $7.51 | $668.63M | $955.40M | -$1.38B | $-12.51 | 2.36M |
| 38 | EBS | Emergent BioSolutions Inc. | $10.70 | $604.55M | $759.80M | $75.90M | $1.34 | 358.39K |
| 39 | KMDA | Kamada Ltd. | $9.08 | $534.31M | $174.79M | $20.44M | $0.35 | 78.63K |
| 40 | ORGO | Organogenesis Holdings Inc. | $3.74 | $489.38M | $464.62M | $1.00M | $0.01 | 233.57K |
| 41 | SIGA | SIGA Technologies, Inc. | $6.78 | $485.48M | $172.25M | $74.47M | $1.04 | 246.47K |
| 42 | ETON | Eton Pharmaceuticals, Inc. | $17.15 | $461.21M | $70.32M | -$6.68M | $-0.25 | 224.82K |
| 43 | AQST | Aquestive Therapeutics, Inc. | $3.88 | $429.07M | $43.40M | -$68.98M | $-0.62 | 2.18M |
| 44 | AKBA | Akebia Therapeutics, Inc. | $1.20 | $329.25M | $225.07M | -$15.90M | $-0.06 | 4.82M |
| 45 | CGC | Canopy Growth Corporation | $1.09 | $298.69M | $203.88M | -$239.17M | $-0.87 | 8.28M |
| 46 | EOLS | Evolus, Inc. | $4.39 | $284.15M | $285.82M | -$58.56M | $-0.90 | 618.68K |
| 47 | LFCR | Lifecore Biomedical, Inc. | $7.16 | $249.30M | $133.82M | -$35.90M | $-0.96 | 92.94K |
| 48 | DERM | Journey Medical Corporation | $8.10 | $202.17M | $59.40M | -$8.66M | $-0.35 | 61.84K |
| 49 | ACB | Aurora Cannabis Inc. | $3.60 | $200.71M | $275.93M | -$46.17M | $-0.81 | 783.47K |
| 50 | OGI | Organigram Global Inc. | $1.27 | $162.15M | $189.81M | -$18.13M | $-0.14 | 411.45K |
| 51 | ANIK | Anika Therapeutics, Inc. | $10.42 | $150.25M | $80.91M | -$33.04M | $-2.29 | 118.87K |
| 52 | TKNO | Alpha Teknova, Inc. | $1.99 | $106.50M | $39.80M | -$18.22M | $-0.34 | 204.12K |
| 53 | CRDL | Cardiol Therapeutics Inc. | $1.04 | $88.12M | $57.68K | -$25.47M | $-0.30 | 187.92K |
| 54 | CTOR | Citius Oncology, Inc. | $1.18 | $86.46M | $0.00 | -$24.76M | $-0.31 | 88.20K |
| 55 | ASRT | Assertio Holdings, Inc. | $12.05 | $85.57M | $137.35M | -$28.92M | $-4.07 | 31.88K |
| 56 | CPIX | Cumberland Pharmaceuticals Inc. | $3.83 | $57.29M | $41.28M | -$3.33M | $-0.22 | 83.48K |
| 57 | INCR | InterCure Ltd. | $0.88 | $49.70M | $101.69M | $5.86M | $0.10 | 8.07K |
| 58 | ZYBT | Zhengye Biotechnology Holding Limited | $0.92 | $43.39M | $26.98M | $1.64M | $0.03 | 5.97K |
| 59 | SCYX | SCYNEXIS, Inc. | $0.76 | $37.92M | $2.93M | -$25.30M | $-0.51 | 105.73K |
| 60 | RMTI | Rockwell Medical, Inc. | $1.03 | $37.11M | $75.58M | -$5.52M | $-0.15 | 261.43K |
| 61 | BGM | BGM Group Ltd. | $1.05 | $33.20M | $25.10M | -$1.44M | $-0.20 | 49.40K |
| 62 | TLPH | Talphera, Inc. | $0.79 | $32.89M | $398.00K | -$12.39M | $-0.30 | 58.82K |
| 63 | TXMD | TherapeuticsMD, Inc. | $2.30 | $26.62M | $2.80M | $302.00K | $0.03 | 47.90K |
| 64 | APUS | Apimeds Pharmaceuticals US, Inc. | $1.15 | $14.46M | $0.00 | -$5.16M | $-0.41 | 22.70K |
| 65 | AYTU | Aytu BioPharma, Inc. | $2.17 | $13.63M | $58.11M | -$17.24M | $-1.72 | 24.60K |
| 66 | CABR | Caring Brands, Inc. | $0.88 | $11.82M | $465.00 | -$1.52M | $-0.15 | 28.80K |
| 67 | GELS | Gelteq Limited | $0.80 | $9.64M | $117.04K | -$4.70M | $-0.72 | 6.26K |
| 68 | IXHL | Incannex Healthcare Inc. | $0.26 | $9.01M | $164.62K | -$51.84M | $-0.17 | 2.49M |
| 69 | BFRI | Biofrontera Inc. | $0.83 | $8.94M | $37.16M | -$17.57M | $-1.63 | 235.24K |
| 70 | IMCC | IM Cannabis Corp. | $1.10 | $5.35M | $38.36M | -$3.51M | $-0.72 | 54.23K |
| 71 | SBFM | Sunshine Biopharma, Inc. | $1.16 | $5.28M | $37.32M | -$5.99M | $-1.32 | 27.77K |
| 72 | FLGC | Flora Growth Corp. | $9.04 | $4.97M | $49.66M | -$15.96M | $-29.01 | 9.04K |
| 73 | SNOA | Sonoma Pharmaceuticals, Inc. | $2.83 | $3.51M | $19.57M | -$3.13M | $-1.83 | 13.72K |
| 74 | YCBD | cbdMD, Inc. | $0.78 | $3.12M | $19.19M | -$2.04M | $-0.23 | 1.76M |
| 75 | CPHI | China Pharma Holdings, Inc. | $0.63 | $2.44M | $4.05M | -$3.19M | $-0.82 | 11.30K |
| 76 | SHPH | Shuttle Pharmaceuticals Holdings, Inc. | $1.08 | $2.41M | $0.00 | -$10.71M | $-4.79 | 54.61K |
| 77 | RDHL | RedHill Biopharma Ltd. | $1.02 | $1.84M | $59.44M | -$76.29M | $-42.31 | 31.02K |
| 78 | SXTC | China SXT Pharmaceuticals, Inc. | $2.51 | $1.01M | $1.74M | -$3.30M | $-8.18 | 120.57K |
| 79 | INM | InMed Pharmaceuticals Inc. | $0.85 | $829.59K | $823.73M | -$2.03B | $-514,280.50 | 14.76K |
| 80 | AKAN | Akanda Corp. | $0.94 | $651.56K | $836.66K | -$4.10M | $-3.93 | 63.60K |
| 81 | PRFX | PainReform Ltd. | $3.34 | $283.71K | $0.00 | -$12.40M | $-146.01 | 159.85K |
| 82 | UPC | Universe Pharmaceuticals INC | $2.68 | $9.32K | $17.86M | -$3.67M | $-1,055.80 | 5.44K |
