| 1 | TAK | Takeda Pharmaceutical Company Limited | $20.43 | $65.57B | $29.41B | $1.14B | $0.41 | 2.56M |
| 2 | TEVA | Teva Pharmaceutical Industries Limited | $39.95 | $46.54B | $17.40B | $716.92M | $0.61 | 5.94M |
| 3 | HLN | Haleon plc | $10.20 | $45.55B | $25.89B | $3.81B | $0.97 | 19.91M |
| 4 | ZTS | Zoetis Inc. | $80.97 | $33.82B | $9.52B | $2.62B | $6.08 | 4.14M |
| 5 | UTHR | United Therapeutics Corporation | $592.84 | $27.15B | $3.15B | $1.31B | $27.86 | 919.15K |
| 6 | VTRS | Viatris Inc. | $18.29 | $21.28B | $14.74B | -$410.70M | −$0.35 | 9.18M |
| 7 | NBIX | Neurocrine Biosciences, Inc. | $145.87 | $15.20B | $3.37B | $705.50M | $6.82 | 1.38M |
| 8 | ELAN | Elanco Animal Health Incorporated | $22.96 | $11.62B | $5.02B | -$199.00M | −$0.40 | 5.36M |
| 9 | RDY | Dr. Reddy's Laboratories Limited | $13.75 | $11.46B | $3.48B | $339.06M | $0.41 | 3.09M |
| 10 | ALKS | Alkermes plc | $44.44 | $7.71B | $1.67B | $66.12M | $0.39 | 2.36M |
| 11 | AMRX | Amneal Pharmaceuticals, Inc. | $21.02 | $6.90B | $3.12B | $157.36M | $0.48 | 3.64M |
| 12 | LNTH | Lantheus Holdings, Inc. | $99.92 | $6.75B | $1.56B | $275.31M | $4.12 | 1.04M |
| 13 | HIMS | Hims & Hers Health, Inc. | $27.59 | $6.39B | $2.58B | -$142.03M | −$0.59 | 9.84M |
| 14 | KNSA | Kiniksa Pharmaceuticals International, plc | $72.98 | $6.09B | $840.85M | $80.66M | $1.00 | 630.21K |
| 15 | LQDA | Liquidia Corporation | $43.74 | $4.44B | $450.91M | $138.61M | $1.43 | 5.48M |
| 16 | RGC | Regencell Bioscience Holdings Limited | $6.76 | $3.34B | $0.00 | -$8.90M | −$0.02 | 309.49K |
| 17 | AMLX | Amylyx Pharmaceuticals, Inc. | $27.09 | $3.01B | $0.00 | -$152.09M | −$1.49 | 1.37M |
| 18 | HCM | HUTCHMED (China) Limited | $14.27 | $2.49B | $549.12M | $17.88M | $0.10 | 51.58K |
| 19 | BHC | Bausch Health Companies Inc. | $6.35 | $2.40B | $10.74B | -$1.08B | −$2.89 | 1.85M |
| 20 | SUPN | Supernus Pharmaceuticals, Inc. | $40.77 | $2.37B | $830.44M | -$109.89M | −$1.91 | 852.30K |
| 21 | PBH | Prestige Consumer Healthcare Inc. | $48.15 | $2.29B | $1.10B | $172.01M | $3.57 | 601.32K |
| 22 | PRGO | Perrigo Company plc | $15.82 | $2.21B | $4.14B | -$1.73B | −$12.49 | 2.75M |
| 23 | BCRX | BioCryst Pharmaceuticals, Inc. | $7.88 | $2.09B | $940.61M | -$384.67M | −$1.63 | 5.46M |
| 24 | TRLV | Trulieve Cannabis Corp. | $10.82 | $2.09B | $1.14B | -$473.30M | −$2.45 | 2.16M |
| 25 | XERS | Xeris Biopharma Holdings, Inc. | $10.21 | $1.76B | $335.41M | -$17.16M | −$0.10 | 3.07M |
| 26 | ETON | Eton Pharmaceuticals, Inc. | $50.17 | $1.64B | $105.59M | $12.69M | $0.41 | 547.91K |
| 27 | PAHC | Phibro Animal Health Corporation | $39.03 | $1.60B | $1.52B | $99.72M | $2.43 | 232.96K |
| 28 | ANIP | ANI Pharmaceuticals, Inc. | $72.60 | $1.59B | $978.38M | $105.83M | $4.93 | 397.70K |
| 29 | PCRX | Pacira BioSciences, Inc. | $36.38 | $1.47B | $746.16M | $14.64M | $0.35 | 1.95M |
| 30 | ALVO | Alvotech | $4.62 | $1.38B | $491.95M | -$179.59M | −$0.56 | 1.23M |
| 31 | CRON | Cronos Group Inc. | $3.31 | $1.24B | $179.03M | $69.73M | $0.18 | 870.94K |
| 32 | AMPH | Amphastar Pharmaceuticals, Inc. | $25.47 | $1.13B | $730.02M | $78.55M | $1.69 | 475.23K |
| 33 | HROW | Harrow, Inc. | $28.95 | $1.08B | $275.59M | -$37.23M | −$0.98 | 631.62K |
| 34 | COLL | Collegium Pharmaceutical, Inc. | $23.21 | $753.41M | $808.21M | $47.91M | $1.26 | 788.75K |
| 35 | IRWD | Ironwood Pharmaceuticals, Inc. | $3.50 | $585.13M | $389.32M | $129.87M | $0.75 | 2.05M |
| 36 | AQST | Aquestive Therapeutics, Inc. | $3.97 | $496.23M | $54.09M | -$78.23M | −$0.65 | 2.19M |
| 37 | EOLS | Evolus, Inc. | $7.17 | $472.71M | $316.49M | -$34.33M | −$0.53 | 724.90K |
| 38 | KMDA | Kamada Ltd. | $7.94 | $459.63M | $192.77M | $22.33M | $0.38 | 92.76K |
| 39 | TLRY | Tilray Brands, Inc. | $2.72 | $362.69M | $963.10M | -$164.22M | −$1.39 | 4.09M |
| 40 | TKNO | Alpha Teknova, Inc. | $6.59 | $353.45M | $43.70M | -$16.77M | −$0.31 | 557.79K |
| 41 | EBS | Emergent BioSolutions Inc. | $6.34 | $327.14M | $747.20M | -$176.80M | −$3.26 | 1.08M |
| 42 | ANIK | Anika Therapeutics, Inc. | $21.27 | $291.76M | $120.65M | -$3.78M | −$0.27 | 99.98K |
| 43 | CGC | Canopy Growth Corporation | $0.67 | $282.11M | $209.47M | -$168.32M | −$0.47 | 2.41M |
| 44 | EVO | Evotec SE | $1.52 | $270.06M | $901.15M | -$158.01M | −$0.51 | 159.70K |
| 45 | LFCR | Lifecore Biomedical, Inc. | $6.44 | $241.98M | $114.72M | -$43.23M | −$1.15 | 584.47K |
| 46 | ACB | Aurora Cannabis Inc. | $3.90 | $240.84M | $205.42M | -$19.58M | −$0.34 | 984.70K |
| 47 | SIGA | SIGA Technologies, Inc. | $3.16 | $226.79M | $53.66M | -$2.76M | −$0.04 | 579.42K |
| 48 | BIOA | BioAge Labs, Inc. | $4.99 | $223.75M | $10.36M | -$94.46M | −$2.37 | 856.54K |
| 49 | AKBA | Akebia Therapeutics, Inc. | $0.64 | $173.57M | $219.06M | -$29.67M | −$0.11 | 8.09M |
| 50 | DERM | Journey Medical Corporation | $4.97 | $136.64M | $68.18M | -$6.10M | −$0.23 | 203.28K |
| 51 | CRDL | Cardiol Therapeutics Inc. | $1.12 | $128.73M | $0.00 | -$22.35M | −$0.21 | 1.34M |
| 52 | OGI | Organigram Global Inc. | $0.94 | $128.20M | $220.55M | $61.79M | $0.46 | 443.02K |
| 53 | ORGO | Organogenesis Holdings Inc. | $0.94 | $120.36M | $456.92M | -$94.20M | −$0.73 | 765.55K |
| 54 | TLPH | Talphera, Inc. | $1.07 | $80.81M | $1.00K | -$15.08M | −$0.27 | 120.99K |
| 55 | ZYBT | Zhengye Biotechnology Holding Limited | $1.42 | $67.24M | $17.45M | -$10.47M | −$0.22 | 1.17M |
| 56 | CPIX | Cumberland Pharmaceuticals Inc. | $4.35 | $65.17M | $31.27M | -$10.77M | −$0.72 | 65.57K |
| 57 | CTOR | Citius Oncology, Inc. | $0.60 | $64.27M | $7.11M | -$46.06M | −$0.49 | 122.16K |
| 58 | BGM | BGM Group Ltd. | $8.40 | $51.97M | $69.37M | -$22.48M | −$0.71 | 8.98K |
| 59 | SCYX | SCYNEXIS, Inc. | $3.81 | $45.05M | $19.21M | -$10.23M | −$1.37 | 396.41K |
| 60 | INCR | InterCure Ltd. | $4.27 | $43.29M | $87.88M | -$11.61M | −$1.08 | 4.35K |
| 61 | IXHL | Incannex Healthcare Inc. | $2.61 | $30.43M | $12.00K | -$29.59M | −$2.54 | 84.20K |
| 62 | RMTI | Rockwell Medical, Inc. | $7.00 | $27.71M | $69.39M | -$5.08M | −$1.32 | 25.32K |
| 63 | CPHI | China Pharma Holdings, Inc. | $0.63 | $25.72M | $3.91M | -$4.47M | −$0.34 | 2.90M |
| 64 | AYTU | Aytu BioPharma, Inc. | $1.93 | $23.78M | $57.57M | -$14.25M | −$1.09 | 40.14K |
| 65 | TXMD | TherapeuticsMD, Inc. | $1.80 | $20.96M | $3.27M | -$217.00K | −$0.02 | 20.14K |
| 66 | OPTH | Optimi Health Corp. | $3.12 | $13.41M | $125.32K | -$4.92M | −$1.41 | 35.63K |
| 67 | BFRI | Biofrontera Inc. | $0.82 | $10.62M | $46.17M | -$6.37M | −$0.54 | 352.52K |
| 68 | CABR | Caring Brands, Inc. | $1.08 | $9.71M | $1.16K | -$9.57M | −$0.75 | 25.26K |
| 69 | INM | InMed Pharmaceuticals Inc. | $1.59 | $7.47M | $2.06B | -$13.32M | −$3.26 | 62.55K |
| 70 | SHPH | Shuttle Pharmaceuticals Holdings, Inc. | $5.05 | $5.12M | $0.00 | -$10.26M | −$20.33 | 42.45K |
| 71 | APUS | Apimeds Pharmaceuticals US, Inc. | $2.90 | $4.96M | $0.00 | -$58.48M | −$50.29 | 7.68M |
| 72 | GELS | Gelteq Limited | $0.45 | $4.69M | $196.84K | -$4.97M | −$0.49 | 1.23M |
| 73 | SNOA | Sonoma Pharmaceuticals, Inc. | $1.12 | $4.31M | $21.92M | -$2.26M | −$1.01 | 45.47K |
| 74 | YCBD | cbdMD, Inc. | $0.36 | $3.87M | $20.93M | -$2.89M | −$0.30 | 324.93K |
| 75 | SBFM | Sunshine Biopharma, Inc. | $2.65 | $3.62M | $35.35M | -$5.83M | −$8.34 | 555.42K |
| 76 | SXTC | China SXT Pharmaceuticals, Inc. | $3.54 | $2.41M | $2.54M | -$7.37M | −$6.72 | 438.44K |
| 77 | RDHL | RedHill Biopharma Ltd. | $0.42 | $1.70M | $9.55M | -$9.31M | −$4.25 | 674.03K |
| 78 | UPC | Universe Pharmaceuticals INC | $2.88 | $1.62M | $37.04M | -$852.71K | −$3.00 | 60.65K |
| 79 | PRFX | PRF Technologies Ltd. | $0.74 | $920.05K | $39.50K | -$8.90M | −$8.88 | 254.88K |
| 80 | AKAN | Akanda Corp. | $1.05 | $824.92K | $1.09M | -$49.67M | −$1,386.19 | 1.03M |
| 81 | IMCC | IM Cannabis Corp. | $0.87 | $268.65K | $32.67M | -$12.95M | −$5.28 | 5.71M |
