| 1 | LLY | Eli Lilly and Company | Drug Manufacturers - General | $1,273.46 | $1.14T | $79.67B | $26.71B | $29.79 | 2.31M |
| 2 | JNJ | Johnson & Johnson | Drug Manufacturers - General | $263.81 | $645.97B | $99.33B | $21.04B | $8.63 | 7.20M |
| 3 | ABBV | AbbVie Inc. | Drug Manufacturers - General | $285.64 | $505.87B | $64.39B | $6.31B | $3.56 | 4.82M |
| 4 | UNH | UnitedHealth Group Incorporated | Healthcare Plans | $418.09 | $377.12B | $450.13B | $14.12B | $15.54 | 5.48M |
| 5 | MRK | Merck & Co., Inc. | Drug Manufacturers - General | $145.27 | $358.82B | $66.49B | $3.17B | $1.28 | 9.86M |
| 6 | NVS | Novartis AG | Drug Manufacturers - General | $151.12 | $289.24B | $56.69B | $12.76B | $6.63 | 1.90M |
| 7 | AZN | AstraZeneca PLC | Drug Manufacturers - General | $171.49 | $267.52B | $61.37B | $10.45B | $6.69 | 2.79M |
| 8 | TMO | Thermo Fisher Scientific Inc. | Diagnostics & Research | $673.82 | $249.99B | $46.34B | $6.98B | $18.62 | 2.47M |
| 9 | AMGN | Amgen Inc. | Drug Manufacturers - General | $439.26 | $238.96B | $38.09B | $8.74B | $16.09 | 2.93M |
| 10 | GILD | Gilead Sciences, Inc. | Drug Manufacturers - General | $156.04 | $193.96B | $30.46B | -$3.24B | −$2.59 | 6.03M |
| 11 | ABT | Abbott Laboratories | Medical Devices | $103.70 | $180.75B | $46.59B | $5.42B | $3.11 | 9.89M |
| 12 | NVO | Novo Nordisk A/S | Drug Manufacturers - General | $39.05 | $173.22B | $49.33B | $17.44B | $3.92 | 12.75M |
| 13 | PFE | Pfizer Inc. | Drug Manufacturers - General | $30.03 | $171.14B | $63.70B | $4.33B | $0.76 | 30.76M |
| 14 | DHR | Danaher Corporation | Diagnostics & Research | $230.50 | $163.10B | $25.11B | $4.00B | $5.63 | 4.86M |
| 15 | ISRG | Intuitive Surgical, Inc. | Medical Instruments & Supplies | $452.29 | $161.60B | $11.03B | $3.14B | $8.72 | 2.33M |
| 16 | VRTX | Vertex Pharmaceuticals Incorporated | Biotechnology | $523.93 | $133.71B | $12.59B | $4.41B | $17.19 | 1.18M |
| 17 | BMY | Bristol-Myers Squibb Company | Drug Manufacturers - General | $61.48 | $125.91B | $49.19B | $9.28B | $4.54 | 13.44M |
| 18 | MDT | Medtronic plc | Medical Devices | $95.41 | $122.61B | $37.54B | $5.23B | $4.06 | 25.05M |
| 19 | CVS | CVS Health Corporation | Healthcare Plans | $93.47 | $120.30B | $414.45B | $4.89B | $3.83 | 9.00M |
| 20 | MCK | McKesson Corporation | Medical Distribution | $1,000.77 | $119.29B | $410.98B | $4.59B | $37.49 | 763.31K |
| 21 | SYK | Stryker Corporation | Medical Devices | $307.15 | $118.56B | $25.84B | $3.73B | $9.65 | 2.66M |
| 22 | HCA | HCA Healthcare, Inc. | Medical Care Facilities | $469.03 | $104.51B | $78.01B | $6.84B | $29.86 | 1.26M |
| 23 | GSK | GSK plc | Drug Manufacturers - General | $50.75 | $103.07B | $44.39B | $6.45B | $3.16 | 4.90M |
| 24 | SNY | Sanofi | Drug Manufacturers - General | $41.60 | $99.56B | $54.76B | $4.43B | $2.09 | 3.34M |
| 25 | ELV | Elevance Health, Inc. | Healthcare Plans | $439.95 | $95.87B | $200.49B | $4.96B | $22.46 | 1.26M |
| 26 | REGN | Regeneron Pharmaceuticals, Inc. | Biotechnology | $805.02 | $85.33B | $15.53B | $4.33B | $40.42 | 731.62K |
| 27 | CI | The Cigna Group | Healthcare Plans | $306.95 | $81.02B | $281.61B | $6.42B | $24.18 | 1.55M |
| 28 | MRNA | Moderna, Inc. | Biotechnology | $200.10 | $79.64B | $2.23B | -$3.15B | −$8.00 | 18.58M |
| 29 | BSX | Boston Scientific Corporation | Medical Devices | $45.69 | $67.38B | $21.00B | $3.67B | $2.46 | 17.02M |
| 30 | TAK | Takeda Pharmaceutical Company Limited | Drug Manufacturers - Specialty & Generic | $20.24 | $64.96B | $29.58B | $1.15B | $0.41 | 2.55M |
| 31 | COR | Cencora, Inc. | Medical Distribution | $331.00 | $64.20B | $332.77B | $2.62B | $13.49 | 1.24M |
| 32 | CAH | Cardinal Health, Inc. | Medical Distribution | $249.57 | $59.15B | $254.06B | $1.71B | $7.22 | 1.83M |
| 33 | NTRA | Natera, Inc. | Diagnostics & Research | $403.95 | $57.88B | $2.71B | -$192.35M | −$1.38 | 1.73M |
| 34 | ARGX | argenx SE | Biotechnology | $873.71 | $56.38B | $7.20B | $2.23B | $33.83 | 429.09K |
| 35 | BDX | Becton, Dickinson and Company | Medical Instruments & Supplies | $198.91 | $54.73B | $20.84B | $941.00M | $3.33 | 1.67M |
| 36 | VEEV | Veeva Systems Inc. | Health Information Services | $323.04 | $53.32B | $3.46B | $1.01B | $6.07 | 1.58M |
| 37 | EW | Edwards Lifesciences Corporation | Medical Devices | $89.07 | $51.45B | $6.51B | $1.00B | $1.73 | 3.57M |
| 38 | HUM | Humana Inc. | Healthcare Plans | $422.07 | $51.13B | $145.68B | $1.28B | $10.60 | 1.42M |
| 39 | A | Agilent Technologies, Inc. | Diagnostics & Research | $173.07 | $48.98B | $7.37B | $1.44B | $5.07 | 2.41M |
| 40 | IQV | IQVIA Holdings Inc. | Diagnostics & Research | $279.36 | $46.74B | $16.98B | $1.38B | $8.08 | 1.47M |
| 41 | TEVA | Teva Pharmaceutical Industries Limited | Drug Manufacturers - Specialty & Generic | $39.41 | $45.91B | $17.40B | $716.92M | $0.61 | 5.89M |
| 42 | HLN | Haleon plc | Drug Manufacturers - Specialty & Generic | $10.27 | $45.86B | $25.96B | $3.82B | $0.97 | 19.87M |
| 43 | WAT | Waters Corporation | Diagnostics & Research | $453.67 | $44.55B | $5.82B | -$54.79M | −$0.68 | 846.78K |
| 44 | IDXX | IDEXX Laboratories, Inc. | Diagnostics & Research | $560.38 | $44.44B | $4.55B | $1.14B | $14.22 | 513.43K |
| 45 | ONC | BeOne Medicines AG | Biotechnology | $377.63 | $43.73B | $918.58M | $98.27M | $0.85 | 377.85K |
| 46 | ILMN | Illumina, Inc. | Diagnostics & Research | $269.42 | $41.22B | $4.49B | $825.00M | $5.37 | 3.71M |
| 47 | RVMD | Revolution Medicines, Inc. | Biotechnology | $186.99 | $39.43B | $0.00 | -$1.77B | −$8.97 | 2.25M |
| 48 | BIIB | Biogen Inc. | Drug Manufacturers - General | $250.69 | $37.28B | $10.03B | $835.09M | $5.65 | 1.23M |
| 49 | RMD | ResMed Inc. | Medical Instruments & Supplies | $252.86 | $36.66B | $5.65B | $1.52B | $10.40 | 1.14M |
| 50 | RPRX | Royalty Pharma plc | Biotechnology | $63.86 | $35.57B | $2.54B | $815.00M | $1.46 | 3.08M |
| 51 | CNC | Centene Corporation | Healthcare Plans | $70.17 | $34.92B | $202.94B | -$5.10B | −$10.32 | 4.43M |
| 52 | ALC | Alcon Inc. | Medical Instruments & Supplies | $70.17 | $34.29B | $10.82B | $640.64M | $1.30 | 1.74M |
| 53 | ZTS | Zoetis Inc. | Drug Manufacturers - Specialty & Generic | $81.03 | $33.85B | $9.52B | $2.62B | $6.08 | 4.14M |
| 54 | MTD | Mettler-Toledo International Inc. | Diagnostics & Research | $1,670.29 | $33.68B | $4.13B | $905.61M | $44.44 | 220.30K |
| 55 | GEHC | GE HealthCare Technologies Inc. | Medical Devices | $71.45 | $32.44B | $21.27B | $1.99B | $4.35 | 3.65M |
| 56 | ALNY | Alnylam Pharmaceuticals, Inc. | Biotechnology | $224.03 | $30.98B | $4.80B | $807.99M | $5.87 | 1.32M |
| 57 | DXCM | DexCom, Inc. | Medical Devices | $77.94 | $30.40B | $4.97B | $999.70M | $2.52 | 4.25M |
| 58 | MDLN | Medline Inc. | Medical Instruments & Supplies | $34.09 | $29.35B | $29.94B | $691.00M | $0.84 | 8.86M |
| 59 | WST | West Pharmaceutical Services, Inc. | Medical Instruments & Supplies | $392.15 | $27.96B | $3.33B | $564.90M | $7.82 | 581.56K |
| 60 | DGX | Quest Diagnostics Incorporated | Diagnostics & Research | $241.89 | $27.09B | $11.56B | $1.06B | $9.46 | 1.15M |
| 61 | GMAB | Genmab A/S | Biotechnology | $43.79 | $27.02B | $4.13B | $788.20M | $1.58 | 4.14M |
| 62 | LH | Labcorp Holdings Inc. | Diagnostics & Research | $328.95 | $26.97B | $14.35B | $1.00B | $12.08 | 725.51K |
| 63 | UTHR | United Therapeutics Corporation | Drug Manufacturers - Specialty & Generic | $587.50 | $26.91B | $3.15B | $1.31B | $27.86 | 913.17K |
| 64 | ROIV | Roivant Sciences Ltd. | Biotechnology | $36.49 | $26.30B | $7.53M | -$266.25M | −$0.37 | 7.51M |
| 65 | PHG | Koninklijke Philips N.V. | Medical Devices | $26.89 | $26.04B | $19.77B | $1.25B | $1.29 | 1.10M |
| 66 | INCY | Incyte Corporation | Biotechnology | $115.71 | $24.09B | $5.82B | $1.61B | $7.85 | 1.72M |
| 67 | STE | STERIS plc | Medical Devices | $232.15 | $22.73B | $6.04B | $805.10M | $8.18 | 700.54K |
| 68 | THC | Tenet Healthcare Corporation | Medical Care Facilities | $268.45 | $22.54B | $22.64B | $2.24B | $25.75 | 659.06K |
| 69 | GH | Guardant Health, Inc. | Diagnostics & Research | $169.08 | $22.47B | $1.18B | -$453.44M | −$3.50 | 1.88M |
| 70 | BNTX | BioNTech SE | Biotechnology | $88.12 | $22.32B | $2.97B | -$1.89B | −$7.63 | 1.01M |
| 71 | VTRS | Viatris Inc. | Drug Manufacturers - Specialty & Generic | $18.00 | $20.94B | $14.74B | -$410.70M | −$0.35 | 9.21M |
| 72 | INSM | Insmed Incorporated | Biotechnology | $93.39 | $20.30B | $1.14B | -$875.31M | −$4.08 | 2.76M |
| 73 | MEDP | Medpace Holdings, Inc. | Diagnostics & Research | $669.20 | $19.25B | $2.78B | $491.50M | $16.89 | 312.61K |
| 74 | ZBH | Zimmer Biomet Holdings, Inc. | Medical Devices | $98.56 | $19.00B | $8.51B | $806.80M | $4.11 | 2.02M |
| 75 | RVTY | Revvity, Inc. | Diagnostics & Research | $158.77 | $17.72B | $2.88B | $231.62M | $2.06 | 2.10M |
| 76 | EXEL | Exelixis, Inc. | Biotechnology | $64.53 | $16.76B | $2.44B | $860.62M | $3.17 | 2.25M |
| 77 | ASND | Ascendis Pharma A/S | Biotechnology | $243.37 | $16.63B | $1.18B | $845.69M | $13.29 | 877.51K |
| 78 | CRL | Charles River Laboratories International, Inc. | Diagnostics & Research | $345.37 | $16.59B | $4.00B | -$238.46M | −$4.88 | 1.09M |
| 79 | HALO | Halozyme Therapeutics, Inc. | Biotechnology | $125.63 | $15.23B | $1.66B | $413.60M | $3.42 | 2.62M |
| 80 | NBIX | Neurocrine Biosciences, Inc. | Drug Manufacturers - Specialty & Generic | $142.70 | $14.87B | $3.37B | $705.50M | $6.82 | 1.37M |
| 81 | JAZZ | Jazz Pharmaceuticals plc | Biotechnology | $214.00 | $14.85B | $4.60B | $940.76M | $14.58 | 805.30K |
| 82 | SOLV | Solventum Corporation | Medical Instruments & Supplies | $85.41 | $14.80B | $8.31B | $1.43B | $8.20 | 928.79K |
| 83 | ICLR | ICON Public Limited Company | Diagnostics & Research | $185.27 | $14.33B | $8.29B | $42.34M | $0.54 | 971.36K |
| 84 | BBIO | BridgeBio Pharma, Inc. | Biotechnology | $68.56 | $13.42B | $713.07M | -$691.87M | −$3.57 | 2.92M |
| 85 | SNN | Smith & Nephew plc | Medical Devices | $30.83 | $13.27B | $12.24B | $1.13B | $2.58 | 1.22M |
| 86 | BTSG | BrightSpring Health Services, Inc. | Health Information Services | $60.11 | $13.24B | $14.37B | $365.97M | $1.67 | 2.33M |
| 87 | BAX | Baxter International Inc. | Medical Instruments & Supplies | $25.30 | $13.11B | $11.47B | -$1.06B | −$2.06 | 6.71M |
| 88 | PEN | Penumbra, Inc. | Medical Devices | $324.39 | $12.84B | $1.50B | $160.59M | $4.07 | 388.52K |
| 89 | MDGL | Madrigal Pharmaceuticals, Inc. | Biotechnology | $434.24 | $12.66B | $1.28B | -$325.10M | −$12.61 | 278.81K |
| 90 | EHC | Encompass Health Corporation | Medical Care Facilities | $124.09 | $12.41B | $6.21B | $621.00M | $6.13 | 1.02M |
| 91 | TEM | Tempus AI, Inc. | Health Information Services | $67.62 | $12.33B | $1.43B | -$254.43M | −$1.43 | 7.02M |
| 92 | DVA | DaVita Inc. | Medical Care Facilities | $183.64 | $12.14B | $14.01B | $847.48M | $11.42 | 700.12K |
| 93 | SMMT | Summit Therapeutics Inc. | Biotechnology | $15.47 | $12.04B | $0.00 | -$856.09M | −$1.12 | 6.75M |
| 94 | COO | The Cooper Companies, Inc. | Medical Instruments & Supplies | $61.21 | $11.84B | $4.24B | $570.30M | $2.91 | 4.15M |
| 95 | AVTR | Avantor, Inc. | Medical Instruments & Supplies | $17.29 | $11.71B | $6.56B | -$578.00M | −$0.85 | 9.43M |
| 96 | ELAN | Elanco Animal Health Incorporated | Drug Manufacturers - Specialty & Generic | $22.52 | $11.39B | $5.02B | -$199.00M | −$0.40 | 5.34M |
| 97 | TECH | Bio-Techne Corporation | Biotechnology | $72.55 | $11.39B | $1.22B | $181.86M | $1.16 | 3.08M |
| 98 | UHS | Universal Health Services, Inc. | Medical Care Facilities | $186.89 | $11.20B | $18.11B | $1.53B | $24.45 | 653.61K |
| 99 | GMED | Globus Medical, Inc. | Medical Devices | $81.41 | $11.18B | $3.14B | $535.46M | $3.91 | 1.54M |
| 100 | ALGN | Align Technology, Inc. | Medical Instruments & Supplies | $154.51 | $11.05B | $4.14B | $413.58M | $5.76 | 963.57K |