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Septerna, Inc.

SEPNNASDAQHealthcareBiotechnology

$37.56
Today:- (-)1Y +55.92%

As of Oct 12, 2026 close

Market cap
$1.69B
P/E (TTM)
-
Forward P/E
-
Dividend yield
-
52-week range
$17.55$51.10
Volume (live)
-
Avg. volume (3M)
381.61K

Septerna (SEPN) Stock Price & Financial Analysis

Septerna Stock Price Chart

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Financial Metrics & Key Statistics

Fundamental metrics, valuation ratios, and profitability indicators

Price & Trading Activity
Day's Range$37.25 - $38.41
52-Week High$51.10
52-Week Low$17.55
Open$38.32
Volume (last close)207.56K
Average Volume (3M)381.61K
Size & Valuation
Market Cap1.69B
Shares Outstanding45.04M
Price to Sales (P/S)17.11
Price to Book (P/B)4.37
EV/EBITDA-36.95
Earnings & Profitability
Revenue (TTM)98.88M
Net Income (TTM)-24.24M
Free Cash Flow (TTM)105.10M
EPS (TTM)$-0.54
Profit Margin-24.51%
Operating Margin-56.68%
Return on Equity (ROE)-6.27%
Debt to Equity0.06
Technical Indicators
50-Day MA$39.45
200-Day MA$31.15
1-Year Change+55.92%
Dividend Information
Annual Dividend$0.00
Dividend Yield0.00%

Compare SEPN with other stocks →

Septerna at a Glance

Septerna (SEPN) has a market capitalization of $1.69B. The stock trades at 17.1× sales. Over the trailing twelve months it lost $24.24M on revenue of $98.88M and generated $105.10M of free cash flow. Revenue grew 13520.1% year over year.

It holds $84.66M in cash and securities against $22.55M of debt, a net cash position of $62.12M.

Septerna does not currently pay a dividend.

The share price is up 55.9% over the past year. At $37.56 it sits within its 52-week range of $17.55 to $51.10, above its 200-day moving average of $31.15.

Based on 11 professional analyst ratings from the past 90 days, the consensus is Buy with an average price target of $52.88, 40.8% above the latest close.

Frequently Asked Questions About Septerna

What is the current stock price for SEPN?

As of the Oct 12, 2026 close, SEPN stock trades at $37.56. The 52-week range is $17.55–$51.10, with a day range of $37.25–$38.41.

What is the P/E ratio for SEPN?

The P/E ratio (Price-to-Earnings) for SEPN is shown in the Key Statistics section. This valuation metric helps compare Septerna, Inc. to industry peers.

Does SEPN pay dividends?

Septerna does not currently pay a regular dividend. The company reinvests earnings into growth and operations. Check the Dividends tab for historical dividend information.

What do analysts recommend for SEPN?

Based on 11 analysts, the consensus for SEPN is Buy.

What is the market cap of SEPN?

Septerna's market capitalization is $1.69B, classifying it as a small-cap company. Septerna operates in the Healthcare sector within the Biotechnology industry.