| 1 | VRTX | Vertex Pharmaceuticals Incorporated | $546.12 | $139.97B | $12.22B | $4.34B | $16.87 | 1.20M |
| 2 | REGN | Regeneron Pharmaceuticals, Inc. | $827.72 | $87.74B | $15.53B | $4.33B | $40.42 | 756.66K |
| 3 | ARGX | argenx SE | $1,033.15 | $66.66B | $6.39B | $2.06B | $31.23 | 283.24K |
| 4 | MRNA | Moderna, Inc. | $145.55 | $57.93B | $2.23B | -$3.15B | $-8.00 | 24.09M |
| 5 | RVMD | Revolution Medicines, Inc. | $210.02 | $41.60B | $0.00 | -$1.37B | $-7.16 | 1.78M |
| 6 | ONC | BeOne Medicines AG | $358.26 | $41.48B | $855.20M | $76.45M | $0.67 | 336.03K |
| 7 | ALNY | Alnylam Pharmaceuticals, Inc. | $266.11 | $36.80B | $4.80B | $807.99M | $5.87 | 2.18M |
| 8 | RPRX | Royalty Pharma plc | $63.96 | $35.79B | $2.44B | $827.60M | $1.48 | 2.71M |
| 9 | SYRE | Spyre Therapeutics, Inc. | $88.98 | $30.79B | $90.49M | -$179.44M | $-0.87 | 1.02M |
| 10 | INSM | Insmed Incorporated | $126.29 | $27.21B | $819.56M | -$1.18B | $-5.70 | 2.67M |
| 11 | INCY | Incyte Corporation | $126.75 | $26.39B | $5.82B | $1.61B | $7.85 | 1.64M |
| 12 | BNTX | BioNTech SE | $103.76 | $26.28B | $3.30B | -$1.46B | $-5.95 | 1.53M |
| 13 | ROIV | Roivant Sciences Ltd. | $34.93 | $24.24B | $8.26M | -$299.77M | $-0.42 | 6.88M |
| 14 | GMAB | Genmab A/S | $33.60 | $21.46B | $3.90B | $821.20M | $1.28 | 2.49M |
| 15 | ASND | Ascendis Pharma A/S | $270.56 | $17.46B | $1.01B | $588.68M | $9.41 | 536.78K |
| 16 | JAZZ | Jazz Pharmaceuticals plc | $246.81 | $16.31B | $4.44B | $29.49M | $0.47 | 1.01M |
| 17 | MDGL | Madrigal Pharmaceuticals, Inc. | $541.08 | $15.77B | $1.28B | -$325.10M | $-11.92 | 328.27K |
| 18 | EXEL | Exelixis, Inc. | $59.01 | $15.26B | $2.42B | $859.04M | $3.16 | 2.51M |
| 19 | BBIO | BridgeBio Pharma, Inc. | $74.84 | $14.58B | $579.96M | -$721.55M | $-3.74 | 2.03M |
| 20 | SMMT | Summit Therapeutics Inc. | $17.61 | $13.70B | $0.00 | -$856.09M | $-1.12 | 5.44M |
| 21 | HALO | Halozyme Therapeutics, Inc. | $110.19 | $13.54B | $1.51B | $348.84M | $2.87 | 2.12M |
| 22 | CORT | Corcept Therapeutics Incorporated | $111.62 | $13.21B | $830.81M | $54.03M | $0.47 | 1.05M |
| 23 | BMRN | BioMarin Pharmaceutical Inc. | $66.53 | $13.15B | $3.24B | $268.74M | $1.37 | 2.15M |
| 24 | ARWR | Arrowhead Pharmaceuticals, Inc. | $86.34 | $12.30B | $622.01M | -$300.91M | $-2.15 | 1.26M |
| 25 | KYMR | Kymera Therapeutics, Inc. | $117.39 | $11.45B | $51.48M | -$315.00M | $-3.55 | 652.11K |
| 26 | TECH | Bio-Techne Corporation | $72.43 | $11.37B | $1.21B | $109.57M | $0.70 | 3.07M |
| 27 | KRYS | Krystal Biotech, Inc. | $358.24 | $10.93B | $417.30M | $225.03M | $7.50 | 291.91K |
| 28 | AXSM | Axsome Therapeutics, Inc. | $206.68 | $10.58B | $708.24M | -$188.30M | $-3.74 | 650.31K |
| 29 | PTGX | Protagonist Therapeutics, Inc. | $145.72 | $10.27B | $74.06M | -$114.71M | $-1.76 | 491.71K |
| 30 | PRAX | Praxis Precision Medicines, Inc. | $351.81 | $10.16B | $0.00 | -$326.53M | $-13.77 | 396.67K |
| 31 | NUVL | Nuvalent, Inc. | $123.96 | $9.75B | $0.00 | -$450.07M | $-6.05 | 941.11K |
| 32 | IONS | Ionis Pharmaceuticals, Inc. | $58.09 | $9.61B | $873.76M | -$564.78M | $-3.46 | 2.39M |
| 33 | APGE | Apogee Therapeutics, Inc. | $135.07 | $9.41B | $0.00 | -$274.62M | $-4.41 | 1.28M |
| 34 | ABVX | ABIVAX Société Anonyme | $114.79 | $9.06B | $3.94M | -$386.26M | $-5.42 | 870.07K |
| 35 | CYTK | Cytokinetics, Incorporated | $72.72 | $8.96B | $105.81M | -$829.61M | $-6.84 | 1.89M |
| 36 | TGTX | TG Therapeutics, Inc. | $55.99 | $8.96B | $700.35M | $461.90M | $2.87 | 2.20M |
| 37 | CRNX | Crinetics Pharmaceuticals, Inc. | $84.95 | $8.84B | $18.07M | -$496.39M | $-5.14 | 2.43M |
| 38 | PCVX | Vaxcyte, Inc. | $61.16 | $8.53B | $0.00 | -$946.53M | $-6.91 | 979.99K |
| 39 | IBRX | ImmunityBio, Inc. | $8.08 | $8.30B | $140.98M | -$854.53M | $-0.89 | 8.41M |
| 40 | IMVT | Immunovant, Inc. | $39.25 | $8.00B | $0.00 | -$505.61M | $-2.77 | 1.12M |
| 41 | BLTE | Belite Bio, Inc | $193.61 | $7.72B | $0.00 | -$90.27M | $-2.54 | 187.81K |
| 42 | CAI | Caris Life Sciences, Inc. | $25.07 | $7.08B | $907.29M | $33.98M | $0.06 | 5.34M |
| 43 | SRRK | Scholar Rock Holding Corporation | $55.33 | $7.04B | $0.00 | -$408.73M | $-3.58 | 1.05M |
| 44 | RYTM | Rhythm Pharmaceuticals, Inc. | $102.74 | $6.98B | $217.16M | -$202.68M | $-3.06 | 620.55K |
| 45 | PTCT | PTC Therapeutics, Inc. | $69.30 | $6.38B | $1.01B | -$38.38M | $-0.45 | 1.06M |
| 46 | CGON | CG Oncology, Inc. | $74.67 | $6.31B | $5.07M | -$186.75M | $-2.37 | 746.59K |
| 47 | CNTA | Centessa Pharmaceuticals plc | $40.50 | $6.22B | $0.00 | -$250.64M | $-1.78 | 0.00 |
| 48 | TVTX | Travere Therapeutics, Inc. | $65.28 | $6.00B | $536.20M | -$21.42M | $-0.23 | 1.54M |
| 49 | MIRM | Mirum Pharmaceuticals, Inc. | $100.90 | $5.94B | $569.61M | -$798.84M | $-14.81 | 624.55K |
| 50 | LGND | Ligand Pharmaceuticals Incorporated | $285.60 | $5.68B | $274.48M | $153.56M | $7.57 | 237.25K |
| 51 | CRSP | CRISPR Therapeutics AG | $55.79 | $5.36B | $4.10M | -$593.30M | $-6.42 | 1.45M |
| 52 | XENE | Xenon Pharmaceuticals Inc. | $59.75 | $5.22B | $0.00 | -$383.17M | $-4.72 | 638.35K |
| 53 | CELC | Celcuity Inc. | $95.70 | $5.21B | $0.00 | -$192.89M | $-3.89 | 868.24K |
| 54 | DNTH | Dianthus Therapeutics, Inc. | $108.10 | $5.19B | $1.34M | -$11.32M | $-0.28 | 668.61K |
| 55 | ORKA | Oruka Therapeutics, Inc. | $92.51 | $5.10B | $0.00 | -$116.25M | $-2.37 | 800.86K |
| 56 | ERAS | Erasca, Inc. | $16.19 | $4.93B | $0.00 | -$277.02M | $-0.96 | 3.46M |
| 57 | ACAD | ACADIA Pharmaceuticals Inc. | $28.02 | $4.84B | $1.10B | $375.65M | $2.20 | 1.66M |
| 58 | EWTX | Edgewise Therapeutics, Inc. | $43.07 | $4.61B | $0.00 | -$176.01M | $-1.67 | 1.22M |
| 59 | DNLI | Denali Therapeutics Inc. | $22.28 | $4.16B | $0.00 | -$508.02M | $-2.88 | 1.29M |
| 60 | DFTX | Definium Therapeutics, Inc. | $38.09 | $4.14B | $0.00 | -$237.54M | $-2.57 | 2.05M |
| 61 | IRD | Opus Genetics, Inc. | $4.67 | $4.06B | $11.98M | -$106.93M | $-0.26 | 1.10M |
| 62 | VKTX | Viking Therapeutics, Inc. | $34.87 | $4.05B | $0.00 | -$534.80M | $-4.67 | 1.85M |
| 63 | TLX | Telix Pharmaceuticals Limited | $11.94 | $4.04B | $803.79M | -$7.13M | $-0.02 | 126.38K |
| 64 | DYN | Dyne Therapeutics, Inc. | $24.28 | $4.02B | $0.00 | -$519.41M | $-3.46 | 1.84M |
| 65 | CPRX | Catalyst Pharmaceuticals, Inc. | $31.49 | $4.00B | $596.96M | $221.32M | $1.74 | 2.52M |
| 66 | LEGN | Legend Biotech Corporation | $21.52 | $3.98B | $1.14B | -$250.18M | $-1.36 | 2.44M |
| 67 | TARS | Tarsus Pharmaceuticals, Inc. | $90.78 | $3.90B | $535.08M | -$48.27M | $-1.13 | 769.48K |
| 68 | ELVN | Enliven Therapeutics, Inc. | $59.32 | $3.73B | $0.00 | -$98.78M | $-1.69 | 998.76K |
| 69 | RCUS | Arcus Biosciences, Inc. | $29.66 | $3.72B | $236.00M | -$369.00M | $-3.31 | 1.14M |
| 70 | IOVA | Iovance Biotherapeutics, Inc. | $8.79 | $3.68B | $285.61M | -$353.86M | $-0.93 | 17.19M |
| 71 | MANE | Veradermics, Incorporated | $98.51 | $3.68B | $0.00 | -$67.14M | $-0.91 | 730.18K |
| 72 | IDYA | IDEAYA Biosciences, Inc. | $39.86 | $3.54B | $225.27M | -$140.06M | $-1.58 | 733.30K |
| 73 | ABCL | AbCellera Biologics Inc. | $11.43 | $3.46B | $79.21M | -$143.96M | $-0.48 | 8.43M |
| 74 | GPCR | Structure Therapeutics Inc. | $47.34 | $3.43B | $0.00 | -$170.34M | $-2.63 | 611.09K |
| 75 | RLAY | Relay Therapeutics, Inc. | $19.04 | $3.42B | $10.68M | -$272.70M | $-1.57 | 2.29M |
| 76 | TNGX | Tango Therapeutics, Inc. | $22.52 | $3.23B | $56.99M | -$107.23M | $-0.88 | 2.19M |
| 77 | ARQT | Arcutis Biotherapeutics, Inc. | $23.90 | $3.09B | $415.62M | -$2.38M | $-0.02 | 1.63M |
| 78 | NAMS | NewAmsterdam Pharma Company N.V. | $25.40 | $3.08B | $22.41M | -$215.05M | $-1.82 | 1.06M |
| 79 | IRON | Disc Medicine, Inc. | $79.23 | $3.07B | $0.00 | -$245.89M | $-6.66 | 387.62K |
| 80 | BEAM | Beam Therapeutics Inc. | $29.66 | $3.06B | $164.01M | -$65.04M | $-0.63 | 1.56M |
| 81 | IMNM | Immunome, Inc. | $26.76 | $3.03B | $4.01M | -$224.59M | $-2.39 | 1.07M |
| 82 | QURE | uniQure N.V. | $44.50 | $2.95B | $18.67M | -$252.21M | $-4.12 | 1.35M |
| 83 | ZLAB | Zai Lab Limited | $26.23 | $2.90B | $453.28M | -$178.12M | $-1.62 | 1.10M |
| 84 | NRIX | Nurix Therapeutics, Inc. | $26.14 | $2.90B | $36.77M | -$341.35M | $-3.41 | 1.13M |
| 85 | MBX | MBX Biosciences, Inc. | $61.72 | $2.87B | $0.00 | -$86.61M | $-2.18 | 434.26K |
| 86 | SRPT | Sarepta Therapeutics, Inc. | $22.50 | $2.74B | $2.18B | $65.06M | $0.60 | 3.05M |
| 87 | CLDX | Celldex Therapeutics, Inc. | $39.68 | $2.64B | $820.00K | -$283.69M | $-4.27 | 808.63K |
| 88 | NUVB | Nuvation Bio Inc. | $6.81 | $2.57B | $143.05M | -$145.99M | $-0.42 | 5.37M |
| 89 | VERA | Vera Therapeutics, Inc. | $35.89 | $2.57B | $0.00 | -$368.95M | $-5.60 | 2.03M |
| 90 | TRVI | Trevi Therapeutics, Inc. | $17.26 | $2.51B | $0.00 | -$45.61M | $-0.32 | 1.51M |
| 91 | HRMY | Harmony Biosciences Holdings, Inc. | $42.25 | $2.48B | $899.11M | $145.62M | $2.48 | 727.27K |
| 92 | SLS | SELLAS Life Sciences Group, Inc. | $13.86 | $2.39B | $0.00 | -$29.46M | $-0.22 | 6.76M |
| 93 | OCUL | Ocular Therapeutix, Inc. | $10.64 | $2.38B | $52.04M | -$290.50M | $-1.45 | 2.52M |
| 94 | COGT | Cogent Biosciences, Inc. | $34.76 | $2.34B | $0.00 | -$354.30M | $-3.66 | 1.67M |
| 95 | VRDN | Viridian Therapeutics, Inc. | $22.92 | $2.34B | $70.92M | -$360.59M | $-4.12 | 1.55M |
| 96 | MLYS | Mineralys Therapeutics, Inc. | $28.21 | $2.34B | $0.00 | -$151.78M | $-2.03 | 816.91K |
| 97 | BHVN | Biohaven Ltd. | $15.69 | $2.32B | $0.00 | -$647.68M | $-5.44 | 2.65M |
| 98 | ADMA | ADMA Biologics, Inc. | $9.62 | $2.31B | $509.86M | $165.35M | $0.68 | 2.14M |
| 99 | MESO | Mesoblast Limited | $17.32 | $2.24B | $17.20M | -$102.14M | $-0.85 | 196.65K |
| 100 | PGEN | Precigen, Inc. | $7.10 | $2.22B | $31.59M | -$204.41M | $-0.67 | 5.48M |
| 101 | AUPH | Aurinia Pharmaceuticals Inc. | $16.08 | $2.21B | $298.30M | $298.21M | $2.16 | 1.11M |
| 102 | URGN | UroGen Pharma Ltd. | $44.09 | $2.21B | $140.49M | -$133.22M | $-2.73 | 860.54K |
| 103 | ZYME | Zymeworks Inc. | $29.19 | $2.18B | $81.26M | -$102.66M | $-1.35 | 610.00K |
| 104 | RAPP | Rapport Therapeutics, Inc. | $45.77 | $2.16B | $20.00M | -$107.28M | $-2.56 | 281.46K |
| 105 | VCEL | Vericel Corporation | $40.19 | $2.10B | $306.30M | $24.22M | $0.47 | 485.62K |
| 106 | GENB | Generate Biomedicines, Inc. | $16.39 | $2.10B | $31.89M | -$203.15M | $-1.99 | 1.13M |
| 107 | PHVS | Pharvaris N.V. | $35.25 | $2.09B | $0.00 | -$198.21M | $-3.15 | 567.08K |
| 108 | TSHA | Taysha Gene Therapies, Inc. | $5.60 | $2.05B | $7.47M | -$129.88M | $-0.39 | 2.52M |
| 109 | XNCR | Xencor, Inc. | $26.61 | $2.00B | $97.36M | -$172.42M | $-2.31 | 1.26M |
| 110 | AGIO | Agios Pharmaceuticals, Inc. | $33.10 | $1.97B | $98.34M | -$411.29M | $-7.01 | 1.04M |
| 111 | COAG | Hemab Therapeutics Holdings, Inc. | $44.41 | $1.96B | — | -$63.91M | $-67.56 | 367.85K |
| 112 | RXRX | Recursion Pharmaceuticals, Inc. | $3.63 | $1.92B | $66.29M | -$559.78M | $-1.17 | 15.96M |
| 113 | IMCR | Immunocore Holdings plc | $36.13 | $1.91B | $385.76M | -$19.78M | $-0.39 | 388.88K |
| 114 | INBX | Inhibrx Biosciences, Inc. | $121.17 | $1.89B | $1.30M | -$130.19M | $-8.39 | 255.71K |
| 115 | KOD | Kodiak Sciences Inc. | $35.36 | $1.88B | $0.00 | -$233.09M | $-4.19 | 577.03K |
| 116 | STOK | Stoke Therapeutics, Inc. | $29.81 | $1.88B | $32.08M | -$169.77M | $-2.85 | 844.88K |
| 117 | LKFT | Lakefront Biotherapeutics NV | $28.49 | $1.88B | $1.21B | $568.33M | $8.63 | 248.81K |
| 118 | NBTX | Nanobiotix S.A. | $38.80 | $1.86B | $26.11M | -$107.08M | $-2.26 | 159.82K |
| 119 | NKTR | Nektar Therapeutics | $74.19 | $1.84B | $55.63M | -$158.10M | $-8.10 | 581.16K |
| 120 | ZBIO | Zenas BioPharma, Inc. | $32.88 | $1.83B | $0.00 | -$425.15M | $-9.14 | 691.40K |
| 121 | SNDX | Syndax Pharmaceuticals, Inc. | $20.56 | $1.81B | $217.17M | -$243.25M | $-2.80 | 1.36M |
| 122 | INVA | Innoviva, Inc. | $21.33 | $1.81B | $424.12M | $504.34M | $5.94 | 643.32K |
| 123 | PVLA | Palvella Therapeutics, Inc. | $157.24 | $1.77B | $0.00 | -$52.54M | $-4.45 | 181.66K |
| 124 | TYRA | Tyra Biosciences, Inc. | $28.65 | $1.77B | $0.00 | -$131.10M | $-2.18 | 602.81K |
| 125 | GHRS | GH Research PLC | $28.23 | $1.75B | $0.00 | -$56.41M | $-0.91 | 281.57K |
| 126 | FTRE | Fortrea Holdings Inc. | $17.70 | $1.68B | $2.68B | -$85.20M | $-0.92 | 1.46M |
| 127 | VIR | Vir Biotechnology, Inc. | $11.39 | $1.68B | $65.31M | -$442.72M | $-3.14 | 1.74M |
| 128 | ATAI | AtaiBeckley Inc. | $7.39 | $1.67B | $3.49M | -$663.40M | $-2.78 | 8.45M |
| 129 | NVAX | Novavax, Inc. | $10.22 | $1.67B | $596.34M | -$87.83M | $-0.52 | 4.56M |
| 130 | SEPN | Septerna, Inc. | $36.75 | $1.64B | $72.25M | -$36.04M | $-0.81 | 391.56K |
| 131 | ANAB | AnaptysBio, Inc. | $56.80 | $1.63B | $232.39M | -$26.79M | $-0.91 | 437.04K |
| 132 | AAPG | Ascentage Pharma Group International | $17.62 | $1.57B | $230.74M | -$243.81M | $-2.95 | 5.80K |
| 133 | RARE | Ultragenyx Pharmaceutical Inc. | $15.30 | $1.54B | $669.43M | -$609.36M | $-6.11 | 3.30M |
| 134 | NTLA | Intellia Therapeutics, Inc. | $12.74 | $1.51B | $66.09M | -$394.60M | $-3.58 | 3.35M |
| 135 | AKTS | Aktis Oncology, Inc. | $27.05 | $1.50B | $7.48M | -$60.50M | $-1.23 | 268.00K |
| 136 | XLO | Xilio Therapeutics, Inc. | $9.00 | $1.47B | $53.48M | -$31.30M | $-0.65 | 14.00K |
| 137 | MAZE | Maze Therapeutics, Inc. | $26.21 | $1.41B | $20.00M | -$122.54M | $-2.63 | 367.31K |
| 138 | TRAX | First Tracks Biotherapeutics, Inc. | $40.46 | $1.41B | $0.00 | -$166.09M | — | 681.55K |
| 139 | BCAX | Bicara Therapeutics Inc. | $23.17 | $1.41B | $0.00 | -$157.31M | $-2.80 | 600.57K |
| 140 | REPL | Replimune Group, Inc. | $15.04 | $1.40B | $0.00 | -$313.94M | $-3.38 | 5.99M |
| 141 | AVBP | ArriVent BioPharma, Inc. | $30.95 | $1.39B | $0.00 | -$145.24M | $-3.62 | 422.78K |
| 142 | LBRX | LB Pharmaceuticals Inc | $49.34 | $1.39B | $0.00 | -$39.17M | $-2.62 | 349.55K |
| 143 | ALMS | Alumis Inc. | $11.10 | $1.39B | $8.40M | -$237.41M | $-2.31 | 2.41M |
| 144 | FBRX | Forte Biosciences, Inc. | $76.99 | $1.37B | $0.00 | -$89.39M | $-1.78 | 2.05M |
| 145 | SVRA | Savara Inc. | $5.37 | $1.36B | $0.00 | -$129.48M | $-0.57 | 1.55M |
| 146 | ORIC | ORIC Pharmaceuticals, Inc. | $12.86 | $1.36B | $0.00 | -$135.21M | $-1.46 | 1.37M |
| 147 | ABSI | Absci Corporation | $8.82 | $1.35B | $1.84M | -$118.44M | $-0.82 | 2.77M |
| 148 | DRTS | Alpha Tau Medical Ltd. | $15.03 | $1.35B | $0.00 | -$56.88M | $-0.67 | 607.95K |
| 149 | SPTX | Seaport Therapeutics, Inc. | $24.86 | $1.32B | — | -$74.88M | $-1.94 | 118.27K |
| 150 | CGEM | Cullinan Therapeutics, Inc. | $22.09 | $1.31B | $0.00 | -$221.04M | $-3.64 | 660.97K |
| 151 | CRVS | Corvus Pharmaceuticals, Inc. | $14.39 | $1.30B | $0.00 | -$44.17M | $-0.53 | 748.76K |
| 152 | IMTX | Immatics N.V. | $9.56 | $1.29B | $43.37M | -$249.30M | $-1.98 | 580.37K |
| 153 | JANX | Janux Therapeutics, Inc. | $20.24 | $1.27B | $21.61M | -$114.48M | $-1.84 | 781.62K |
| 154 | MNKD | MannKind Corporation | $4.06 | $1.25B | $360.78M | -$23.91M | $-0.08 | 3.94M |
| 155 | UNCY | Unicycive Therapeutics, Inc. | $5.16 | $1.23B | $0.00 | -$39.95M | $-0.37 | 745.66K |
| 156 | VYNE | VYNE Therapeutics Inc. | $28.56 | $1.22B | $454.00K | -$21.46M | $-0.66 | 71.15K |
| 157 | OMER | Omeros Corporation | $18.95 | $1.20B | $9.89M | $198.04M | $2.81 | 2.13M |
| 158 | KURA | Kura Oncology, Inc. | $13.25 | $1.17B | $71.64M | -$294.57M | $-3.35 | 1.99M |
| 159 | ANRO | Alto Neuroscience, Inc. | $35.55 | $1.17B | $0.00 | -$74.31M | $-2.50 | 430.89K |
| 160 | DBVT | DBV Technologies S.A. | $13.47 | $1.17B | $1.60M | -$175.85M | $-2.04 | 293.41K |
| 161 | JBIO | Jade Biosciences, Inc. | $19.90 | $1.15B | $0.00 | -$129.61M | $-2.96 | 776.46K |
| 162 | MGTX | MeiraGTx Holdings plc | $13.89 | $1.13B | $79.76M | -$120.53M | $-1.49 | 634.09K |
| 163 | SLDB | Solid Biosciences Inc. | $10.25 | $1.13B | $0.00 | -$191.78M | $-1.95 | 879.15K |
| 164 | OLMA | Olema Pharmaceuticals, Inc. | $10.75 | $1.11B | $0.00 | -$185.15M | $-2.03 | 930.55K |
| 165 | MRVI | Maravai LifeSciences Holdings, Inc. | $7.32 | $1.07B | $204.73M | -$104.56M | $-0.72 | 3.80M |
| 166 | MLTX | MoonLake Immunotherapeutics | $15.01 | $1.07B | $0.00 | -$257.08M | $-3.92 | 1.22M |
| 167 | SANA | Sana Biotechnology, Inc. | $3.85 | $1.07B | $0.00 | -$241.99M | $-0.94 | 2.48M |
| 168 | CLYM | Climb Bio, Inc. | $15.52 | $1.06B | $0.00 | -$52.79M | $-0.84 | 1.42M |
| 169 | GERN | Geron Corporation | $1.57 | $1.05B | $196.12M | -$67.31M | $-0.10 | 11.45M |
| 170 | CBUS | Cibus, Inc. | $1.59 | $1.04B | $4.29M | -$101.42M | $-0.51 | 140.48K |
| 171 | FDMT | 4D Molecular Therapeutics, Inc. | $14.97 | $1.02B | $88.24M | -$160.90M | $-2.70 | 927.91K |
| 172 | ABUS | Arbutus Biopharma Corporation | $5.15 | $1.01B | $191.44M | $160.72M | $0.83 | 3.37M |
| 173 | MNPR | Monopar Therapeutics Inc. | $117.56 | $1.00B | $0.00 | -$14.98M | $-2.04 | 241.33K |
| 174 | WVE | Wave Life Sciences Ltd. | $4.86 | $991.48M | $65.37M | -$202.47M | $-1.08 | 3.37M |
| 175 | RIGL | Rigel Pharmaceuticals, Inc. | $48.67 | $958.12M | $299.77M | $364.23M | $19.21 | 295.84K |
| 176 | ANNX | Annexon, Inc. | $4.87 | $945.75M | $0.00 | -$196.48M | $-1.18 | 2.43M |
| 177 | DSGN | Design Therapeutics, Inc. | $15.14 | $930.12M | $0.00 | -$69.71M | $-1.20 | 515.58K |
| 178 | ARDX | Ardelyx, Inc. | $3.78 | $929.33M | $427.68M | -$58.06M | $-0.24 | 4.49M |
| 179 | GLUE | Monte Rosa Therapeutics, Inc. | $13.84 | $907.13M | $42.95M | -$130.01M | $-1.89 | 1.38M |
| 180 | LXRX | Lexicon Pharmaceuticals, Inc. | $2.24 | $896.54M | $69.64M | -$26.09M | $-0.07 | 2.74M |
| 181 | IVA | Inventiva S.A. | $4.78 | $892.91M | $15.91M | -$624.43M | $-2.94 | 759.05K |
| 182 | TBPH | Theravance Biopharma, Inc. | $17.08 | $875.85M | $109.78M | $114.54M | $2.21 | 485.56K |
| 183 | NGNE | Neurogene Inc. | $38.60 | $861.00M | $0.00 | -$98.64M | $-4.93 | 200.56K |
| 184 | PHAR | Pharming Group N.V. | $11.23 | $841.71M | $369.45M | $9.23M | $0.13 | 21.20K |
| 185 | VSTM | Verastem, Inc. | $8.20 | $813.01M | $49.59M | -$193.96M | $-2.35 | 1.99M |
| 186 | CADL | Candel Therapeutics, Inc. | $12.78 | $796.99M | $0.00 | -$54.42M | $-0.97 | 1.20M |
| 187 | PHAT | Phathom Pharmaceuticals, Inc. | $9.50 | $795.60M | $239.66M | -$99.07M | $-1.27 | 1.50M |
| 188 | ACRS | Aclaris Therapeutics, Inc. | $6.17 | $794.76M | $8.37M | -$69.66M | $-0.56 | 1.92M |
| 189 | CRMD | CorMedix Inc. | $8.43 | $783.86M | $400.05M | $181.01M | $2.10 | 1.28M |
| 190 | STTK | Shattuck Labs, Inc. | $6.79 | $762.07M | $0.00 | -$49.87M | $-0.59 | 829.61K |
| 191 | FBIO | Fortress Biotech, Inc. | $2.72 | $758.93M | $65.83M | $108.35M | $1.14 | 611.03K |
| 192 | ZVRA | Zevra Therapeutics, Inc. | $12.40 | $746.86M | $122.29M | $124.22M | $2.16 | 1.05M |
| 193 | OCS | Oculis Holding AG | $12.17 | $716.88M | $623.00K | -$117.51M | $-2.14 | 230.48K |
| 194 | XOMA | XOMA Royalty Corporation | $40.17 | $699.64M | $36.23M | $31.51M | $1.76 | 691.37K |
| 195 | ZURA | Zura Bio Limited | $6.23 | $699.15M | $0.00 | -$75.43M | $-0.76 | 1.26M |
| 196 | SLN | Silence Therapeutics plc | $14.59 | $689.15M | $838.29K | -$75.01M | $-1.59 | 1.50M |
| 197 | MDXG | MiMedx Group, Inc. | $4.57 | $675.43M | $355.17M | $6.24M | $0.04 | 1.33M |
| 198 | CTMX | CytomX Therapeutics, Inc. | $3.71 | $657.68M | $35.54M | -$59.14M | $-0.37 | 2.82M |
| 199 | PRME | Prime Medicine, Inc. | $3.70 | $655.26M | $4.03M | -$198.37M | $-1.29 | 2.58M |
| 200 | CBIO | Crescent Biopharma, Inc. | $20.88 | $637.51M | $11.88M | -$165.12M | $-6.76 | 243.34K |
| 201 | GYRE | Crescent Biopharma, Inc. | $6.86 | $626.62M | $117.05M | -$6.29M | $-0.06 | 52.23K |
| 202 | BNTC | Benitec Biopharma Inc. | $12.68 | $626.22M | $0.00 | -$48.88M | $-1.10 | 152.78K |
| 203 | CTNM | Contineum Therapeutics, Inc. | $16.70 | $625.71M | $0.00 | -$57.56M | $-1.72 | 475.49K |
| 204 | DRUG | Bright Minds Biosciences Inc. | $65.16 | $624.87M | $0.00 | -$19.94M | $-2.52 | 149.21K |
| 205 | MPLT | MapLight Therapeutics, Inc. | $13.77 | $623.46M | $0.00 | -$199.48M | $-4.98 | 1.23M |
| 206 | ASMB | Assembly Biosciences, Inc. | $36.60 | $618.55M | $71.10M | -$6.38M | $-0.53 | 242.54K |
| 207 | HELP | Cybin Inc. | $12.22 | $611.04M | $0.00 | -$147.96M | $-4.90 | 1.71M |
| 208 | ARVN | Arvinas, Inc. | $9.39 | $600.96M | $89.40M | -$221.30M | $-3.22 | 793.63K |
| 209 | AUTL | Autolus Therapeutics plc | $2.24 | $596.16M | $92.62M | -$288.96M | $-1.09 | 2.79M |
| 210 | VALN | Valneva SE | $6.89 | $592.85M | $181.77M | -$160.50M | $-1.91 | 133.21K |
| 211 | EIKN | Eikon Therapeutics, Inc. | $10.86 | $587.94M | $0.00 | -$302.08M | $-19.30 | 428.36K |
| 212 | TECX | Tectonic Therapeutic, Inc. | $30.75 | $577.15M | $0.00 | -$83.49M | $-4.46 | 217.96K |
| 213 | SGP | SpyGlass Pharma, Inc. | $28.94 | $576.71M | $0.00 | -$43.60M | $-6.66 | 76.51K |
| 214 | NVCT | Nuvectis Pharma, Inc. | $24.49 | $573.42M | $0.00 | -$29.59M | $-1.33 | 211.50K |
| 215 | SPRY | ARS Pharmaceuticals, Inc. | $5.62 | $558.05M | $98.99M | -$197.98M | $-2.00 | 1.90M |
| 216 | OABI | OmniAb, Inc. | $4.33 | $555.68M | $28.91M | -$54.28M | $-0.46 | 1.92M |
| 217 | CAPR | Capricor Therapeutics, Inc. | $9.40 | $539.88M | $0.00 | -$114.59M | $-2.32 | 11.21M |
| 218 | IMMX | Immix Biopharma, Inc. | $13.91 | $532.56M | $0.00 | -$34.98M | $-1.01 | 1.54M |
| 219 | PRTA | Prothena Corporation plc | $9.82 | $531.35M | $57.94M | -$151.18M | $-2.80 | 422.09K |
| 220 | XFOR | X4 Pharmaceuticals, Inc. | $4.04 | $510.21M | $9.01M | -$99.72M | $-1.39 | 614.26K |
| 221 | AURA | Aura Biosciences, Inc. | $7.56 | $509.90M | $0.00 | -$112.39M | $-1.79 | 706.31K |
| 222 | KYTX | Kyverna Therapeutics, Inc. | $8.25 | $498.58M | $0.00 | -$156.40M | $-3.22 | 734.89K |
| 223 | PBYI | Puma Biotechnology, Inc. | $9.55 | $485.57M | $227.18M | $24.38M | $0.48 | 307.22K |
| 224 | ANL | Adlai Nortye Ltd. | $15.01 | $479.94M | $6.49M | -$54.06M | $-6.97 | 154.16K |
| 225 | RZLT | Rezolute, Inc. | $4.58 | $476.50M | $0.00 | -$81.48M | $-0.80 | 1.26M |
| 226 | EPRX | Eupraxia Pharmaceuticals Inc. | $8.40 | $476.39M | $0.00 | -$44.26M | $-0.98 | 482.92K |
| 227 | CCCC | C4 Therapeutics, Inc. | $3.76 | $474.04M | $34.86M | -$103.80M | $-1.07 | 2.41M |
| 228 | CNTN | Canton Strategic Holdings, Inc. | $2.28 | $473.57M | $0.00 | -$80.72M | $-1.30 | 683.76K |
| 229 | ALLO | Allogene Therapeutics, Inc. | $1.97 | $473.37M | $0.00 | -$173.76M | $-0.77 | 5.58M |
| 230 | RGNX | REGENXBIO Inc. | $8.94 | $468.71M | $87.82M | -$290.01M | $-5.59 | 1.26M |
| 231 | AVIR | Atea Pharmaceuticals, Inc. | $5.83 | $461.73M | $0.00 | -$169.52M | $-2.12 | 314.45K |
| 232 | ACHV | Achieve Life Sciences, Inc. | $8.49 | $453.21M | $0.00 | -$51.99M | $-1.08 | 1.29M |
| 233 | PRLD | Prelude Therapeutics Incorporated | $5.46 | $450.56M | $16.72M | -$77.80M | $-1.05 | 537.02K |
| 234 | ARCT | Arcturus Therapeutics Holdings Inc. | $15.82 | $449.62M | $46.15M | -$78.67M | $-2.86 | 1.19M |
| 235 | CMPX | Compass Therapeutics, Inc. | $2.38 | $443.63M | $0.00 | -$68.17M | $-0.40 | 3.03M |
| 236 | FENC | Fennec Pharmaceuticals Inc. | $12.39 | $440.44M | $50.96M | -$8.38M | $-0.27 | 231.18K |
| 237 | PALI | Palisade Bio, Inc. | $2.09 | $438.20M | $0.00 | -$24.15M | $-0.35 | 1.52M |
| 238 | OCGN | Ocugen, Inc. | $1.36 | $435.78M | $4.46M | -$71.67M | $-0.23 | 3.93M |
| 239 | RCKT | Rocket Pharmaceuticals, Inc. | $3.86 | $432.84M | $0.00 | -$209.38M | $-1.88 | 1.47M |
| 240 | KROS | Keros Therapeutics, Inc. | $11.32 | $428.57M | $33.18M | -$85.14M | $-2.17 | 194.32K |
| 241 | ALT | Altimmune, Inc. | $3.42 | $425.66M | $36.00K | -$91.08M | $-0.92 | 4.94M |
| 242 | DNA | Ginkgo Bioworks Holdings, Inc. | $6.95 | $413.97M | $141.31M | -$304.39M | $-5.40 | 1.16M |
| 243 | EVMN | Evommune, Inc. | $12.27 | $413.13M | $10.00M | -$75.99M | $-2.42 | 440.92K |
| 244 | LXEO | Lexeo Therapeutics, Inc. | $4.89 | $396.99M | $0.00 | -$87.50M | $-1.34 | 809.37K |
| 245 | IMUX | Immunic, Inc. | $13.11 | $395.09M | $0.00 | -$104.29M | $-5.33 | 208.57K |
| 246 | EYPT | EyePoint, Inc. | $4.58 | $393.88M | $7.62M | -$271.60M | $-3.51 | 5.32M |
| 247 | CABA | Cabaletta Bio, Inc. | $3.47 | $388.73M | $0.00 | -$175.43M | $-1.85 | 4.21M |
| 248 | AVTX | Avalo Therapeutics, Inc. | $19.23 | $386.66M | $59.00K | -$84.74M | $-5.34 | 770.79K |
| 249 | RLMD | Relmada Therapeutics, Inc. | $4.43 | $383.62M | $0.00 | -$58.88M | $-1.06 | 1.09M |
| 250 | DMAC | DiaMedica Therapeutics Inc. | $6.75 | $363.11M | $0.00 | -$35.10M | $-0.73 | 143.59K |
| 251 | SGMT | Sagimet Biosciences Inc. | $10.94 | $356.20M | $0.00 | -$43.51M | $-1.34 | 1.22M |
| 252 | LEXX | Lexaria Bioscience Corp. | $14.15 | $351.00M | $368.00K | -$7.73M | $-0.34 | 63.86K |
| 253 | FHTX | Foghorn Therapeutics Inc. | $4.92 | $342.14M | $28.22M | -$75.32M | $-1.17 | 332.32K |
| 254 | ABEO | Abeona Therapeutics Inc. | $6.00 | $339.73M | $14.54M | $66.14M | $1.09 | 1.38M |
| 255 | ELDN | Eledon Pharmaceuticals, Inc. | $3.02 | $339.52M | $0.00 | -$78.15M | $-0.91 | 1.02M |
| 256 | UPB | Upstream Bio, Inc. | $6.01 | $326.54M | $3.32M | -$156.76M | $-2.90 | 616.73K |
| 257 | LRMR | Larimar Therapeutics, Inc. | $3.83 | $326.25M | $0.00 | -$166.00M | $-2.12 | 1.06M |
| 258 | CLLS | Cellectis S.A. | $3.24 | $325.71M | $69.56M | -$67.29M | $-0.67 | 16.45K |
| 259 | VNDA | Vanda Pharmaceuticals Inc. | $5.43 | $322.87M | $217.78M | -$239.55M | $-4.05 | 916.04K |
| 260 | SION | Sionna Therapeutics, Inc. | $7.18 | $322.54M | $0.00 | -$85.56M | $-1.92 | 3.29M |
| 261 | WHWK | Whitehawk Therapeutics, Inc. | $4.60 | $318.49M | $7.14M | -$115.81M | $-1.67 | 360.28K |
| 262 | EDIT | Editas Medicine, Inc. | $3.23 | $316.15M | $38.69M | -$108.95M | $-1.21 | 2.21M |
| 263 | AGEN | Agenus Inc. | $8.24 | $315.47M | $123.87M | $64.61M | $1.92 | 1.35M |
| 264 | LYEL | Lyell Immunopharma, Inc. | $14.37 | $314.36M | $31.00K | -$246.41M | $-12.94 | 144.37K |
| 265 | VBIO | Valion Bio, Inc. | $2.77 | $311.63M | $1.54M | -$13.48M | $-0.45 | 767.18K |
| 266 | ENTA | Enanta Pharmaceuticals, Inc. | $14.08 | $301.03M | $69.21M | -$61.98M | $-2.67 | 211.72K |
| 267 | BCYC | Bicycle Therapeutics plc | $4.30 | $300.16M | $61.20M | -$190.41M | $-2.74 | 288.15K |
| 268 | TRDA | Entrada Therapeutics, Inc. | $7.13 | $298.29M | $5.74M | -$166.12M | $-4.00 | 329.06K |
| 269 | FATE | Fate Therapeutics, Inc. | $2.48 | $297.68M | $6.32M | -$129.91M | $-1.09 | 1.75M |
| 270 | GALT | Galectin Therapeutics Inc. | $4.61 | $294.59M | $0.00 | -$24.23M | $-0.37 | 352.48K |
| 271 | FULC | Fulcrum Therapeutics, Inc. | $3.85 | $293.43M | $0.00 | -$76.12M | $-1.15 | 1.68M |
| 272 | PROK | ProKidney Corp. | $2.01 | $285.27M | $889.00K | -$74.84M | $-0.55 | 1.06M |
| 273 | ACIU | AC Immune SA | $2.86 | $282.21M | $4.58M | -$81.86M | $-0.82 | 210.46K |
| 274 | LCTX | Lineage Cell Therapeutics, Inc. | $1.08 | $282.07M | $14.78M | -$64.21M | $-0.27 | 870.74K |
| 275 | VTVT | vTv Therapeutics Inc. | $33.35 | $280.93M | $36.84M | $2.25M | $0.29 | 80.67K |
| 276 | ZNTL | Zentalis Pharmaceuticals, Inc. | $3.99 | $280.35M | $0.00 | -$124.13M | $-1.74 | 1.05M |
| 277 | MGNX | MacroGenics, Inc. | $4.40 | $279.18M | $157.08M | -$70.36M | $-1.11 | 511.68K |
| 278 | ARTV | Artiva Biotherapeutics, Inc. | $11.19 | $276.15M | $0.00 | -$87.07M | $-3.55 | 308.96K |
| 279 | ALEC | Alector, Inc. | $2.46 | $272.05M | $18.42M | -$125.39M | $-1.20 | 1.31M |
| 280 | NAGE | Niagen Bioscience, Inc. | $3.17 | $268.07M | $130.42M | $18.64M | $0.22 | 581.22K |
| 281 | AVXL | Anavex Life Sciences Corp. | $2.86 | $265.05M | $0.00 | -$34.09M | $-0.39 | 881.68K |
| 282 | IVVD | Invivyd, Inc. | $0.83 | $255.79M | $55.87M | -$77.60M | $-0.40 | 3.87M |
| 283 | CAMP | Camp4 Therapeutics Corporation | $4.41 | $255.44M | $3.93M | -$86.30M | $-2.20 | 269.65K |
| 284 | SRZN | Surrozen, Inc. | $22.76 | $249.20M | $7.49M | -$342.56M | $-36.87 | 252.60K |
| 285 | RNAC | Cartesian Therapeutics, Inc. | $9.27 | $248.95M | $1.77M | -$151.77M | $-5.77 | 120.44K |
| 286 | PYXS | Pyxis Oncology, Inc. | $3.89 | $246.90M | $13.86M | -$81.73M | $-1.31 | 1.27M |
| 287 | IKT | Inhibikase Therapeutics, Inc. | $2.50 | $245.78M | $0.00 | -$50.96M | $-0.54 | 478.82K |
| 288 | CGEN | Compugen Ltd. | $2.59 | $244.90M | $72.66M | $34.85M | $0.37 | 303.59K |
| 289 | RNA | Atrium Therapeutics, Inc. | $14.19 | $242.73M | $36.82M | -$396.46M | $-5.26 | 143.18K |
| 290 | YDES | YD Bio Limited | $3.54 | $236.19M | $392.81K | -$11.98M | $-0.18 | 132.19K |
| 291 | NMRA | Neumora Therapeutics, Inc. | $1.31 | $235.63M | $0.00 | -$222.39M | $-1.33 | 705.80K |
| 292 | GLSI | Greenwich LifeSciences, Inc. | $15.95 | $232.32M | $0.00 | -$21.76M | $-1.55 | 125.01K |
| 293 | PLX | Protalix BioTherapeutics, Inc. | $2.67 | $221.74M | $76.38M | $15.33M | $0.19 | 757.40K |
| 294 | PRQR | ProQR Therapeutics N.V. | $2.07 | $218.10M | $15.64M | -$53.15M | $-0.50 | 859.93K |
| 295 | NKTX | Nkarta, Inc. | $2.92 | $216.83M | $0.00 | -$99.93M | $-1.35 | 571.16K |
| 296 | ARMP | Armata Pharmaceuticals, Inc. | $5.84 | $213.34M | $2.96M | -$282.61M | $-7.78 | 99.24K |
| 297 | EQ | Equillium, Inc. | $2.21 | $212.78M | $0.00 | -$19.05M | $-0.26 | 451.39K |
| 298 | IMRX | Immuneering Corporation | $4.82 | $212.14M | $0.00 | -$54.44M | $-1.33 | 634.87K |
| 299 | ORMP | Oramed Pharmaceuticals Inc. | $5.01 | $210.27M | $0.00 | $135.02M | $3.19 | 209.74K |
| 300 | ADCT | ADC Therapeutics SA | $1.36 | $209.63M | $79.17M | -$136.99M | $-0.99 | 1.51M |
| 301 | VYGR | Voyager Therapeutics, Inc. | $3.51 | $208.83M | $36.49M | -$116.64M | $-1.98 | 457.32K |
| 302 | ACOG | Alpha Cognition Inc. | $9.52 | $208.74M | $10.83M | -$25.14M | $-1.31 | 141.88K |
| 303 | OVID | Ovid Therapeutics Inc. | $2.80 | $206.46M | $7.12M | -$24.17M | $-0.32 | 1.45M |
| 304 | ABOS | Acumen Pharmaceuticals, Inc. | $3.18 | $201.04M | $0.00 | -$113.28M | $-1.85 | 359.74K |
| 305 | ANTX | AN2 Therapeutics, Inc. | $5.89 | $200.61M | $0.00 | -$34.55M | $-1.11 | 214.91K |
| 306 | SABS | SAB Biotherapeutics, Inc. | $3.72 | $199.24M | $0.00 | -$398.43K | $-0.01 | 349.65K |
| 307 | SLGL | Sol-Gel Technologies Ltd. | $69.52 | $197.22M | $18.46M | $6.41M | $2.29 | 66.67K |
| 308 | OBIO | Orchestra BioMed Holdings, Inc. | $5.08 | $195.03M | $32.72M | -$54.64M | $-1.31 | 290.50K |
| 309 | NERV | Minerva Neurosciences, Inc. | $4.43 | $194.48M | $0.00 | -$415.07M | $-23.67 | 139.86K |
| 310 | CHRS | Coherus Oncology, Inc. | $1.42 | $193.69M | $46.88M | $195.64M | $1.60 | 1.08M |
| 311 | LENZ | LENZ Therapeutics, Inc. | $5.96 | $186.86M | $20.99M | -$109.00M | $-3.66 | 741.99K |
| 312 | IPHA | Innate Pharma S.A. | $2.08 | $186.35M | $17.92M | -$114.46M | $-1.35 | 287.30K |
| 313 | IPSC | Century Therapeutics, Inc. | $2.11 | $182.63M | $0.00 | -$107.78M | $-1.25 | 510.50K |
| 314 | TNXP | Tonix Pharmaceuticals Holding Corp. | $13.14 | $180.11M | $17.56M | -$147.39M | $-14.12 | 466.25K |
| 315 | MENS | Jyong Biotech Ltd. | $2.39 | $174.50M | $0.00 | -$4.67M | $-0.06 | 39.42K |
| 316 | MDWD | MediWound Ltd. | $13.29 | $171.10M | $14.48M | -$26.11M | $-2.20 | 84.54K |
| 317 | QTTB | Q32 Bio Inc. | $11.99 | $169.00M | $53.74M | $33.24M | $2.60 | 454.19K |
| 318 | LGVN | Longeveron Inc. | $6.81 | $168.79M | $1.22M | -$22.43M | $-1.11 | 62.64K |
| 319 | TARA | Protara Therapeutics, Inc. | $3.94 | $168.77M | $0.00 | -$63.31M | $-1.46 | 364.49K |
| 320 | NGEN | NervGen Pharma Corp. | $2.33 | $168.53M | $0.00 | -$46.74M | $-0.62 | 520.81K |
| 321 | MOLN | Molecular Partners AG | $4.35 | $163.14M | $0.00 | -$76.21M | $-2.04 | 1.14K |
| 322 | ODTX | Odyssey Therapeutics, Inc. | $28.76 | $162.66M | $2.98M | -$146.47M | $-68.99 | 157.79K |
| 323 | IFRX | InflaRx N.V. | $2.22 | $160.49M | $34.10K | -$49.90M | $-0.73 | 951.06K |
| 324 | QNCX | Quince Therapeutics, Inc. | $31.32 | $156.90M | $0.00 | -$33.04M | $-12.56 | 30.00K |
| 325 | IBIO | iBio, Inc. | $1.31 | $156.68M | $300.00K | -$27.38M | $-0.38 | 673.91K |
| 326 | MIST | Milestone Pharmaceuticals Inc. | $1.20 | $156.34M | $1.78M | -$68.36M | $-0.79 | 1.64M |
| 327 | RANI | Rani Therapeutics Holdings, Inc. | $0.87 | $155.75M | $3.17M | -$29.44M | $-0.29 | 650.41K |
| 328 | CRBU | Caribou Biosciences, Inc. | $1.57 | $150.50M | $11.20M | -$133.22M | $-1.41 | 1.03M |
| 329 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | $11.08 | $147.55M | $0.00 | -$84.53M | $-6.61 | 464.37K |
| 330 | BMEA | Biomea Fusion, Inc. | $2.03 | $146.77M | $0.00 | -$44.95M | $-0.73 | 1.44M |
| 331 | ENTX | Entera Bio Ltd. | $3.00 | $143.27M | $0.00 | -$12.38M | $-0.26 | 3.43M |
| 332 | CURX | Curanex Pharmaceuticals Inc | $5.05 | $143.14M | $0.00 | -$7.24M | $-0.27 | 17.07K |
| 333 | KRRO | Korro Bio, Inc. | $12.24 | $141.97M | $3.84M | -$113.50M | $-11.41 | 94.33K |
| 334 | ATRA | Atara Biotherapeutics, Inc. | $9.76 | $137.43M | $23.14M | -$9.47M | $-0.72 | 50.58K |
| 335 | ADAG | Adagene Inc. | $3.58 | $135.19M | $7.80M | -$51.08M | $-1.38 | 239.36K |
| 336 | TTRX | Turn Therapeutics Inc. | $9.80 | $134.69M | $0.00 | -$2.32M | $-0.08 | 56.17K |
| 337 | CDXS | Codexis, Inc. | $1.46 | $132.52M | $78.09M | -$31.99M | $-0.36 | 1.18M |
| 338 | CUE | Cue Biopharma, Inc. | $27.44 | $131.92M | $32.73M | -$19.52M | $-5.19 | 191.76K |
| 339 | PEPG | PepGen Inc. | $3.11 | $131.31M | $0.00 | -$77.22M | $-2.04 | 877.22K |
| 340 | EVAX | Evaxion A/S | $3.12 | $130.11M | $7.53M | -$9.76M | $-0.50 | 389.72K |
| 341 | ENGN | enGene Therapeutics Inc. | $1.82 | $126.90M | $0.00 | -$66.40M | $-1.11 | 673.25K |
| 342 | BDTX | Black Diamond Therapeutics, Inc. | $2.12 | $121.33M | $0.00 | -$43.21M | $-0.76 | 604.92K |
| 343 | VANI | Vivani Medical, Inc. | $1.49 | $121.09M | $0.00 | -$27.09M | $-0.41 | 181.88K |
| 344 | HUMA | Humacyte, Inc. | $0.60 | $119.68M | $2.02M | -$97.59M | $-0.58 | 7.88M |
| 345 | PYPD | PolyPid Ltd. | $5.39 | $118.17M | $0.00 | -$33.63M | $-1.78 | 148.68K |
| 346 | AARD | Aardvark Therapeutics, Inc. | $5.38 | $117.37M | $0.00 | -$69.87M | $-3.21 | 124.45K |
| 347 | ICU | SeaStar Medical Holding Corporation | $2.98 | $116.77M | $1.44M | -$11.90M | $-1.02 | 65.37K |
| 348 | JUNS | Jupiter Neurosciences, Inc. | $3.28 | $115.64M | $40.45K | -$9.18M | $-0.27 | 1.86M |
| 349 | NAUT | Nautilus Biotechnology, Inc. | $0.90 | $115.05M | $10.00K | -$56.52M | $-0.45 | 820.07K |
| 350 | NRXP | NRx Pharmaceuticals, Inc. | $3.49 | $112.82M | $2.29M | -$24.54M | $-0.94 | 1.05M |
| 351 | SEER | Seer, Inc. | $1.95 | $109.19M | $14.92M | -$70.49M | $-1.25 | 649.93K |
| 352 | ALXO | ALX Oncology Holdings Inc. | $2.01 | $109.11M | $0.00 | -$88.87M | $-1.65 | 923.52K |
| 353 | GNLX | Genelux Corporation | $2.44 | $107.73M | $8.00K | -$33.58M | $-0.85 | 332.85K |
| 354 | TNYA | Tenaya Therapeutics, Inc. | $0.68 | $104.51M | $225.00K | -$83.00M | $-0.51 | 1.87M |
| 355 | INTS | Intensity Therapeutics, Inc. | $4.10 | $103.89M | $0.00 | -$10.69M | $-1.42 | 34.22K |
| 356 | ANIX | Anixa Biosciences, Inc. | $3.07 | $103.13M | $0.00 | -$10.07M | $-0.31 | 249.85K |
| 357 | ACET | Adicet Bio, Inc. | $9.59 | $103.04M | $0.00 | -$108.83M | $-13.40 | 91.90K |
| 358 | HURA | TuHURA Biosciences, Inc. | $2.14 | $102.56M | $0.00 | -$28.17M | $-0.52 | 241.89K |
| 359 | CNTB | Connect Biopharma Holdings Limited | $1.84 | $102.41M | $233.00K | -$66.82M | $-1.19 | 699.63K |
| 360 | CNXU | Conexeu Sciences Inc. | $4.97 | $102.23M | — | -$7.20M | $-0.40 | 229.22K |
| 361 | INO | Inovio Pharmaceuticals, Inc. | $1.43 | $98.82M | $0.00 | -$84.93M | $-0.54 | 5.61M |
| 362 | TENX | Tenax Therapeutics, Inc. | $1.94 | $98.69M | $0.00 | $2.17M | $0.05 | 8.82M |
| 363 | NTHI | NeOnc Technologies Holdings, Inc. | $5.03 | $96.64M | $0.00 | -$48.48M | $-2.34 | 217.86K |
| 364 | RLYB | Rallybio Corporation | $16.93 | $96.28M | $858.00K | -$7.82M | $-1.41 | 17.39K |
| 365 | DTIL | Precision BioSciences, Inc. | $7.47 | $95.81M | $45.07M | $190.00K | $0.01 | 268.76K |
| 366 | ONCY | Oncolytics Biotech Inc. | $0.84 | $94.69M | $0.00 | -$29.84M | $-0.30 | 694.33K |
| 367 | PLYX | Polaryx Therapeutics, Inc. | $2.00 | $94.44M | $0.00 | -$6.48M | $-0.14 | 107.06K |
| 368 | KLRS | Kalaris Therapeutics, Inc. | $3.90 | $92.52M | $0.00 | -$44.10M | $-2.10 | 59.33K |
| 369 | CGTX | Cognition Therapeutics, Inc. | $1.03 | $91.87M | $0.00 | -$19.58M | $-0.24 | 490.00K |
| 370 | RNXT | RenovoRx, Inc. | $2.39 | $90.90M | $1.49M | -$12.27M | $-0.33 | 1.00M |
| 371 | NBP | NovaBridge Biosciences | $1.80 | $90.30M | $0.00 | -$47.52M | $-0.54 | 251.55K |
| 372 | ICCC | ImmuCell Corporation | $9.90 | $89.56M | $29.93M | -$545.40K | $-0.06 | 27.07K |
| 373 | ALDX | Aldeyra Therapeutics, Inc. | $1.48 | $89.27M | $0.00 | -$27.37M | $-0.45 | 737.56K |
| 374 | LIMN | Liminatus Pharma, Inc. | $3.71 | $88.13M | $0.00 | -$11.00M | $-0.45 | 449.77K |
| 375 | PBLS | Parabilis Medicines, Inc. | $40.42 | $82.86M | — | -$186.93M | $-92.40 | 368.69K |
| 376 | ACRV | Acrivon Therapeutics, Inc. | $2.13 | $82.48M | $0.00 | -$77.27M | $-2.00 | 350.13K |
| 377 | PMN | ProMIS Neurosciences, Inc. | $12.60 | $82.25M | $0.00 | -$40.62M | $-13.97 | 99.80K |
| 378 | PTHS | Pelthos Therapeutics Inc. | $24.35 | $80.64M | $27.70M | -$51.59M | $-20.29 | 77.27K |
| 379 | MNOV | MediciNova, Inc. | $1.63 | $80.23M | $596.64K | -$11.72M | $-0.24 | 40.63K |
| 380 | COYA | Coya Therapeutics, Inc. | $4.76 | $79.64M | $7.94M | -$21.13M | $-1.26 | 116.41K |
| 381 | SPRB | Spruce Biosciences, Inc. | $57.93 | $79.48M | $0.00 | -$37.19M | $-45.16 | 67.19K |
| 382 | ATHE | Alterity Therapeutics Limited | $4.54 | $77.03M | $5.45M | -$24.68M | $-2.02 | 13.03K |
| 383 | DWTX | Dogwood Therapeutics, Inc. | $2.29 | $76.82M | $0.00 | -$28.32M | $-2.20 | 65.43K |
| 384 | GANX | Gain Therapeutics, Inc. | $1.80 | $76.01M | $0.00 | -$21.24M | $-0.60 | 446.14K |
| 385 | CRDF | Cardiff Oncology, Inc. | $1.09 | $74.50M | $525.00K | -$44.76M | $-0.67 | 750.67K |
| 386 | SKYE | Skye Bioscience, Inc. | $1.86 | $73.81M | $0.00 | -$57.33M | $-1.45 | 131.21K |
| 387 | NTRB | Nutriband Inc. | $5.97 | $72.57M | $1.80M | -$8.08M | $-0.68 | 29.80K |
| 388 | CSBR | Champions Oncology, Inc. | $5.22 | $72.49M | $59.42M | -$1.08M | $-0.08 | 9.96K |
| 389 | PLRX | Pliant Therapeutics, Inc. | $1.16 | $71.69M | $0.00 | -$113.22M | $-1.84 | 395.93K |
| 390 | SPRO | Spero Therapeutics, Inc. | $1.21 | $69.31M | $54.77M | $15.23M | $0.27 | 619.10K |
| 391 | PMVP | PMV Pharmaceuticals, Inc. | $1.29 | $68.80M | $0.00 | -$78.34M | $-1.48 | 553.44K |
| 392 | XBIT | XBiotech Inc. | $2.20 | $67.07M | $0.00 | -$40.16M | $-1.32 | 42.52K |
| 393 | ELOX | Eloxx Pharmaceuticals, Inc. | $15.00 | $65.73M | $0.00 | -$11.95M | $-9.08 | 53.04K |
| 394 | NRXS | NeurAxis, Inc. | $5.96 | $65.25M | $4.28M | -$7.28M | $-0.76 | 90.19K |
| 395 | HRTX | Heron Therapeutics, Inc. | $0.34 | $65.22M | $150.71M | -$30.94M | $-0.18 | 2.68M |
| 396 | INMB | INmune Bio Inc. | $2.44 | $64.87M | $0.00 | -$41.60M | $-1.61 | 327.46K |
| 397 | ALGS | Aligos Therapeutics, Inc. | $6.21 | $64.60M | $4.71M | -$90.32M | $-8.70 | 120.24K |
| 398 | BOLD | Boundless Bio, Inc. | $2.87 | $64.31M | $0.00 | -$55.99M | $-2.50 | 195.63K |
| 399 | APM | Aptorum Group Limited | $8.41 | $61.83M | $431.38K | -$1.36M | $-0.19 | 346.95K |
| 400 | HYFT | MindWalk Holdings Corp. | $1.32 | $61.66M | $11.28M | -$10.11M | $-0.22 | 135.17K |
| 401 | VERU | Veru Inc. | $2.64 | $60.85M | $0.00 | -$21.14M | $-1.07 | 236.62K |
| 402 | OKYO | OKYO Pharma Limited | $1.57 | $58.65M | $0.00 | -$7.30M | $-0.20 | 65.71K |
| 403 | IBO | Impact BioMedical Inc. | $0.54 | $58.20M | $39.00K | -$12.86M | $-0.31 | 168.64K |
| 404 | EXOZ | eXoZymes, Inc. | $6.85 | $57.94M | $0.00 | -$9.67M | $-1.15 | 5.08K |
| 405 | VRCA | Verrica Pharmaceuticals Inc. | $5.30 | $56.46M | $37.16M | -$17.83M | $-1.77 | 87.39K |
| 406 | OSTX | OS Therapies Incorporated | $1.88 | $55.00M | $0.00 | -$44.20M | $-1.31 | 379.48K |
| 407 | MCRB | Seres Therapeutics, Inc. | $5.72 | $54.81M | $1.50M | -$46.90M | $-5.22 | 63.85K |
| 408 | IMA | ImageneBio, Inc. | $4.85 | $54.37M | $0.00 | -$45.07M | $-5.16 | 11.05K |
| 409 | IMMP | Immutep Limited | $0.36 | $53.67M | $9.24M | -$92.22M | $-0.66 | 123.70K |
| 410 | GUTS | Fractyl Health, Inc. | $0.70 | $52.82M | $0.00 | -$108.00M | $-1.26 | 1.30M |
| 411 | FTH | Faeth Therapeutics, Inc. | $40.05 | $51.87M | $-4.85M | -$184.46M | $-145.30 | 301.51K |
| 412 | TIL | Instil Bio, Inc. | $7.58 | $51.41M | $0.00 | -$47.38M | $-7.04 | 7.77K |
| 413 | TCRX | TScan Therapeutics, Inc. | $0.39 | $50.86M | $9.14M | -$124.31M | $-0.96 | 780.64K |
| 414 | INKT | MiNK Therapeutics, Inc. | $11.64 | $49.70M | $0.00 | -$10.83M | $-2.38 | 8.18K |
| 415 | OKUR | OnKure Therapeutics, Inc. | $3.58 | $48.95M | $0.00 | -$58.75M | $-4.33 | 148.99K |
| 416 | CLGN | CollPlant Biotechnologies Ltd. | $3.55 | $48.80M | $389.00K | -$13.13M | $-1.03 | 693.13K |
| 417 | ATYR | aTyr Pharma, Inc. | $0.50 | $48.76M | $190.00K | -$70.03M | $-0.73 | 622.53K |
| 418 | HOWL | Werewolf Therapeutics, Inc. | $0.97 | $46.96M | $21.00M | -$34.61M | $-0.73 | 13.71M |
| 419 | AVLN | Avalyn Pharma Inc. | $37.39 | $46.02M | — | -$85.20M | $-2.04 | 177.22K |
| 420 | KPTI | Karyopharm Therapeutics Inc. | $1.79 | $44.24M | $151.12M | -$194.97M | $-13.00 | 2.21M |
| 421 | MGX | Metagenomi Therapeutics, Inc. | $1.17 | $43.97M | $22.33M | -$85.89M | $-2.29 | 133.20K |
| 422 | ELTX | Elicio Therapeutics, Inc. | $2.41 | $43.89M | $0.00 | -$40.19M | $-2.42 | 291.67K |
| 423 | CELU | Celularity Inc. | $1.68 | $43.01M | $26.55M | -$116.24M | $-4.54 | 8.16M |
| 424 | MAIA | MAIA Biotechnology, Inc. | $1.32 | $42.39M | $0.00 | -$24.25M | $-0.76 | 372.20K |
| 425 | GOSS | Gossamer Bio, Inc. | $0.18 | $41.04M | $55.54M | -$180.40M | $-0.79 | 37.79M |
| 426 | NXTC | NextCure, Inc. | $7.82 | $40.97M | $0.00 | -$54.66M | $-15.85 | 299.73K |
| 427 | MREO | Mereo BioPharma Group plc | $0.25 | $40.09M | $500.00K | -$35.70M | $-0.22 | 6.89M |
| 428 | DMRA | Damora Therapeutics, Inc. | $30.06 | $39.89M | $0.00 | -$235.09M | $-168.71 | 339.67K |
| 429 | TELO | Telomir Pharmaceuticals, Inc. | $1.16 | $39.88M | $0.00 | -$9.22M | $-0.28 | 55.77K |
| 430 | LIXT | Lixte Biotechnology Holdings, Inc. | $3.66 | $39.85M | $0.00 | -$7.22M | $-0.42 | 303.94K |
| 431 | APLM | Apollomics, Inc. | $27.50 | $39.76M | $1.02M | -$226.46M | $-256.74 | 22.18K |
| 432 | FLNA | Filana Therapeutics, Inc. | $0.82 | $39.62M | $0.00 | -$42.28M | $-0.88 | 266.66K |
| 433 | EDSA | Edesa Biotech, Inc. | $4.73 | $39.04M | $0.00 | -$10.44M | $-1.38 | 81.43K |
| 434 | ANVS | Annovis Bio, Inc. | $1.39 | $38.71M | $0.00 | -$40.92M | $-1.78 | 795.08K |
| 435 | KAPA | Kairos Pharma, Ltd. | $1.84 | $38.66M | $0.00 | -$5.84M | $-0.30 | 98.22K |
| 436 | KZIA | Kazia Therapeutics Limited | $12.31 | $38.41M | $1.82M | -$36.58M | $-23.99 | 283.97K |
| 437 | CALC | CalciMedica, Inc. | $2.17 | $35.43M | $0.00 | -$19.54M | $-1.27 | 83.30K |
| 438 | VRXA | VERAXA Biotech AG | $1.76 | $35.16M | $0.00 | $6.74M | $0.26 | 323.35K |
| 439 | HYPD | Hyperion DeFi, Inc. | $3.30 | $35.02M | $1.04M | -$32.99M | $-2.66 | 453.07K |
| 440 | ACTU | Actuate Therapeutics, Inc. | $1.48 | $34.83M | $0.00 | -$21.54M | $-0.98 | 395.23K |
| 441 | GRCE | Grace Therapeutics, Inc. | $2.10 | $34.67M | $0.00 | -$7.79M | $-0.47 | 200.88K |
| 442 | KYNB | Kyntra Bio, Inc. | $8.55 | $34.60M | $7.44M | $111.45M | $27.55 | 14.91K |
| 443 | CNTX | Context Therapeutics Inc. | $0.36 | $34.43M | $0.00 | -$40.23M | $-0.42 | 2.05M |
| 444 | SER | Serina Therapeutics, Inc. | $2.73 | $32.89M | $130.00K | -$21.27M | $-2.00 | 48.98K |
| 445 | LONA | LeonaBio, Inc. | $7.56 | $32.32M | $0.00 | -$129.41M | $-31.56 | 42.79K |
| 446 | ATNM | Actinium Pharmaceuticals, Inc. | $1.03 | $32.17M | $90.00K | -$23.47M | $-0.75 | 146.24K |
| 447 | BRNS | Barinthus Biotherapeutics plc | $0.76 | $31.00M | $0.00 | -$52.31M | $-1.29 | 55.88K |
| 448 | IGC | IGC Pharma, Inc. | $0.30 | $28.32M | $1.19M | -$6.55M | $-0.07 | 855.75K |
| 449 | CING | Cingulate Inc. | $5.10 | $27.70M | $0.00 | -$27.71M | $-4.81 | 146.87K |
| 450 | ESLA | Estrella Immunopharma, Inc. | $0.65 | $27.22M | $0.00 | -$13.25M | $-0.35 | 27.66K |
| 451 | RNTX | Rein Therapeutics Inc. | $0.89 | $26.99M | $0.00 | -$75.35M | $-2.71 | 465.55K |
| 452 | BCTX | BriaCell Therapeutics Corp. | $3.57 | $25.88M | $0.00 | -$30.68M | $-9.58 | 439.93K |
| 453 | TVGN | Tevogen Bio Holdings Inc. | $7.34 | $25.59M | $0.00 | -$21.49M | $-5.96 | 9.00K |
| 454 | GLMD | Galmed Pharmaceuticals Ltd. | $3.88 | $25.57M | $0.00 | -$11.12M | $-1.97 | 39.76K |
| 455 | PSTV | Plus Therapeutics, Inc. | $3.84 | $25.51M | $5.18M | -$11.93M | $-2.13 | 114.73K |
| 456 | BYSI | BeyondSpring Inc. | $0.62 | $25.42M | $0.00 | -$7.64M | $-0.19 | 1.38M |
| 457 | RADX | Radiopharm Theranostics Limited | $2.08 | $24.57M | $2.62M | -$27.67M | $-3.98 | 77.12K |
| 458 | ABVC | ABVC BioPharma, Inc. | $0.96 | $24.43M | $0.00 | -$9.42M | $-0.42 | 105.52K |
| 459 | GNPX | Genprex, Inc. | $3.50 | $24.33M | $0.00 | -$16.73M | $-7.72 | 330.28K |
| 460 | NNVC | NanoViricides, Inc. | $1.12 | $24.20M | $0.00 | -$8.21M | $-0.44 | 295.67K |
| 461 | TLSA | Tiziana Life Sciences Ltd | $1.02 | $24.13M | $0.00 | -$34.95M | $-0.62 | 910.07K |
| 462 | CRVO | CervoMed Inc. | $2.56 | $23.70M | $2.08M | -$30.04M | $-3.25 | 313.40K |
| 463 | MRKR | Marker Therapeutics, Inc. | $1.18 | $22.79M | $2.09M | -$10.90M | $-0.67 | 69.73K |
| 464 | XTLB | XTL Biopharmaceuticals Ltd. | $2.53 | $22.67M | $0.00 | -$915.00K | $-0.10 | 9.30K |
| 465 | ATOS | Atossa Therapeutics, Inc. | $2.52 | $21.73M | $0.00 | -$37.64M | $-4.37 | 55.83K |
| 466 | CMMB | Chemomab Therapeutics Ltd. | $2.71 | $21.62M | $0.00 | -$7.45M | $-1.07 | 95.59K |
| 467 | LTRN | Lantern Pharma Inc. | $1.91 | $21.44M | $0.00 | -$15.91M | $-1.45 | 112.08K |
| 468 | QNRX | Quoin Pharmaceuticals, Ltd. | $7.26 | $20.55M | $0.00 | -$16.98M | $-10.44 | 1.11M |
| 469 | ALLR | Allarity Therapeutics, Inc. | $1.42 | $20.42M | $665.00K | -$12.30M | $-0.81 | 74.75K |
| 470 | NEUP | Neuphoria Therapeutics Inc. | $3.77 | $20.40M | $-13.27K | -$16.50M | $-4.68 | 54.66K |
| 471 | DYAI | Dyadic International, Inc. | $0.52 | $18.93M | $2.16M | -$7.29M | $-0.22 | 185.19K |
| 472 | GNTA | Genenta Science S.p.A. | $0.96 | $18.92M | $0.00 | -$17.92M | $-0.94 | 47.82K |
| 473 | TVRD | Tvardi Therapeutics, Inc. | $1.91 | $17.92M | $2.57M | -$26.88M | $-2.87 | 264.30K |
| 474 | CYCN | Cyclerion Therapeutics, Inc. | $4.25 | $17.87M | $1.99M | -$5.28M | $-1.54 | 54.72K |
| 475 | OTLK | Outlook Therapeutics, Inc. | $0.67 | $16.98M | $333.14K | -$60.96M | $-1.44 | 20.37M |
| 476 | LPCN | Lipocine Inc. | $2.45 | $16.65M | $2.00M | -$11.43M | $-1.97 | 38.68K |
| 477 | BIVI | BioVie Inc. | $2.00 | $15.09M | $0.00 | -$19.96M | $-3.54 | 8.55M |
| 478 | PASG | Passage Bio, Inc. | $4.65 | $14.91M | $0.00 | -$37.68M | $-11.84 | 13.50K |
| 479 | QNTM | Quantum BioPharma Ltd. | $3.24 | $14.55M | $0.00 | -$31.16M | $-8.26 | 233.39K |
| 480 | GRDX | GridAI Technologies Corp. | $3.25 | $14.47M | $74.46K | -$8.69M | $-2.78 | 127.42K |
| 481 | CLDI | Calidi Biotherapeutics, Inc. | $1.39 | $14.28M | $0.00 | -$19.03M | $-3.01 | 139.63K |
| 482 | PTN | Palatin Technologies, Inc. | $12.70 | $13.95M | $12.88M | -$6.25M | $-6.08 | 72.50K |
| 483 | PLUR | Pluri Inc. | $1.36 | $13.67M | $1.08M | -$26.16M | $-2.90 | 25.37K |
| 484 | CVM | CEL-SCI Corporation | $1.63 | $13.27M | $0.00 | -$22.70M | $-3.32 | 182.47K |
| 485 | ASBP | Aspire Biopharma Holdings, Inc. | $8.87 | $13.26M | $34.55K | -$11.76M | $-15.31 | 31.16K |
| 486 | CTXR | Citius Pharmaceuticals, Inc. | $0.59 | $13.15M | $5.61M | -$46.20M | $-2.56 | 836.78K |
| 487 | HIND | Vyome Holdings, Inc. | $2.22 | $13.14M | $152.72K | -$10.93M | $-2.94 | 7.84K |
| 488 | NRSN | NeuroSense Therapeutics Ltd. | $0.51 | $13.02M | $0.00 | -$11.13M | $-0.44 | 492.05K |
| 489 | NCEL | NewcelX Ltd. | $3.35 | $12.88M | $0.00 | -$16.12M | $-4.19 | 10.98K |
| 490 | COCP | Cocrystal Pharma, Inc. | $1.13 | $12.76M | $225.00K | -$9.20M | $-0.74 | 71.07K |
| 491 | PHIO | Phio Pharmaceuticals Corp. | $1.08 | $12.55M | $0.00 | -$10.93M | $-1.31 | 161.58K |
| 492 | IMRN | Immuron Limited | $1.80 | $12.33M | $9.41M | -$6.13M | $-1.01 | 4.10M |
| 493 | PDSB | PDS Biotechnology Corporation | $0.22 | $12.21M | $0.00 | -$33.36M | $-0.69 | 2.18M |
| 494 | BLRX | BioLineRx Ltd. | $2.67 | $11.84M | $1.40M | -$7.90M | $-1.89 | 20.00K |
| 495 | BCDA | BioCardia, Inc. | $1.08 | $11.68M | $0.00 | -$7.78M | $-0.95 | 219.88K |
| 496 | TPST | Tempest Therapeutics, Inc. | $1.03 | $11.26M | $0.00 | -$43.10M | $-7.39 | 226.42K |
| 497 | JSPR | Jasper Therapeutics, Inc. | $0.71 | $10.87M | $0.00 | -$55.65M | $-2.93 | 644.46K |
| 498 | VOR | Vor Biopharma Inc. | $25.05 | $10.77M | $0.00 | -$883.08M | $-151.95 | 756.21K |
| 499 | XBIO | Xenetic Biosciences, Inc. | $4.67 | $10.70M | $3.19M | -$2.23M | $-1.17 | 61.46K |
| 500 | KPRX | Kiora Pharmaceuticals, Inc. | $2.55 | $10.65M | $0.00 | -$11.06M | $-2.66 | 14.34K |
