| 1 | VRTX | Vertex Pharmaceuticals Incorporated | $473.09 | $121.25B | $12.22B | $4.34B | $16.87 | 1.76M |
| 2 | REGN | Regeneron Pharmaceuticals, Inc. | $651.91 | $70.21B | $14.92B | $4.42B | $41.05 | 908.73K |
| 3 | ARGX | argenx SE | $924.60 | $61.05B | $5.31B | $1.63B | $24.76 | 355.32K |
| 4 | ONC | BeOne Medicines AG | $326.77 | $37.83B | $847.22M | $75.73M | $0.66 | 366.07K |
| 5 | RVMD | Revolution Medicines, Inc. | $188.75 | $37.39B | $0.00 | -$1.37B | $-7.16 | 2.82M |
| 6 | ALNY | Alnylam Pharmaceuticals, Inc. | $268.74 | $37.15B | $4.29B | $577.22M | $4.26 | 1.48M |
| 7 | SYRE | Spyre Therapeutics, Inc. | $99.99 | $34.60B | $90.49M | -$179.44M | $-0.87 | 1.58M |
| 8 | RPRX | Royalty Pharma plc | $59.02 | $33.03B | $2.44B | $827.60M | $1.57 | 3.28M |
| 9 | ROIV | Roivant Sciences Ltd. | $35.10 | $24.35B | $8.26M | -$299.77M | $-0.42 | 5.74M |
| 10 | INCY | Incyte Corporation | $116.69 | $24.13B | $5.36B | $1.43B | $7.06 | 1.87M |
| 11 | BNTX | BioNTech SE | $92.06 | $23.28B | $3.20B | -$1.44B | $-5.88 | 903.07K |
| 12 | INSM | Insmed Incorporated | $107.41 | $23.14B | $819.56M | -$1.18B | $-5.70 | 3.84M |
| 13 | MRNA | Moderna, Inc. | $57.02 | $22.52B | $2.23B | -$3.19B | $-8.16 | 8.49M |
| 14 | GMAB | Genmab A/S | $29.17 | $18.63B | $3.90B | $821.20M | $1.28 | 1.88M |
| 15 | JAZZ | Jazz Pharmaceuticals plc | $254.87 | $16.85B | $4.44B | $29.49M | $0.47 | 802.81K |
| 16 | ASND | Ascendis Pharma A/S | $252.66 | $16.30B | $991.39M | $577.03M | $9.22 | 792.05K |
| 17 | BBIO | BridgeBio Pharma, Inc. | $82.93 | $16.15B | $579.96M | -$725.93M | $-3.75 | 4.07M |
| 18 | MDGL | Madrigal Pharmaceuticals, Inc. | $543.35 | $15.77B | $1.13B | -$309.44M | $-12.87 | 382.80K |
| 19 | EXEL | Exelixis, Inc. | $55.65 | $14.88B | $2.38B | $833.42M | $3.00 | 2.63M |
| 20 | AXSM | Axsome Therapeutics, Inc. | $241.53 | $12.37B | $708.24M | -$188.30M | $-3.74 | 1.05M |
| 21 | ARWR | Arrowhead Pharmaceuticals, Inc. | $86.78 | $12.36B | $622.01M | -$300.91M | $-2.16 | 2.79M |
| 22 | BMRN | BioMarin Pharmaceutical Inc. | $58.87 | $11.64B | $3.24B | $268.74M | $1.37 | 1.77M |
| 23 | SMMT | Summit Therapeutics Inc. | $14.98 | $11.62B | $0.00 | -$1.21B | $-1.59 | 5.05M |
| 24 | TECH | Bio-Techne Corporation | $71.77 | $11.26B | $1.21B | $109.57M | $0.70 | 6.40M |
| 25 | KYMR | Kymera Therapeutics, Inc. | $110.38 | $10.77B | $51.48M | -$315.00M | $-3.55 | 1.07M |
| 26 | ABVX | ABIVAX Société Anonyme | $131.16 | $10.26B | $3.96M | -$383.07M | $-5.51 | 2.02M |
| 27 | CYTK | Cytokinetics, Incorporated | $81.92 | $10.10B | $105.81M | -$829.61M | $-6.84 | 2.22M |
| 28 | CORT | Corcept Therapeutics Incorporated | $96.66 | $10.09B | $769.10M | $46.50M | $0.40 | 1.11M |
| 29 | KRYS | Krystal Biotech, Inc. | $327.50 | $9.99B | $417.30M | $225.03M | $7.50 | 535.87K |
| 30 | HALO | Halozyme Therapeutics, Inc. | $80.84 | $9.93B | $1.51B | $348.84M | $2.87 | 1.83M |
| 31 | NUVL | Nuvalent, Inc. | $123.96 | $9.75B | $0.00 | -$450.07M | $-6.05 | 3.88M |
| 32 | PTGX | Protagonist Therapeutics, Inc. | $135.43 | $9.55B | $74.06M | -$114.71M | $-1.76 | 815.84K |
| 33 | APGE | Apogee Therapeutics, Inc. | $134.26 | $9.35B | $0.00 | -$274.62M | $-4.41 | 4.39M |
| 34 | PRAX | Praxis Precision Medicines, Inc. | $322.40 | $9.31B | $0.00 | -$326.53M | $-13.77 | 506.87K |
| 35 | IONS | Ionis Pharmaceuticals, Inc. | $55.87 | $9.22B | $1.06B | -$326.58M | $-1.95 | 3.71M |
| 36 | TGTX | TG Therapeutics, Inc. | $55.50 | $8.88B | $700.35M | $461.90M | $2.87 | 2.73M |
| 37 | FBRX | Forte Biosciences, Inc. | $59.70 | $8.79B | $0.00 | -$89.39M | $-0.99 | 756.12K |
| 38 | CRNX | Crinetics Pharmaceuticals, Inc. | $83.65 | $8.71B | $18.07M | -$496.39M | $-5.14 | 5.98M |
| 39 | IMVT | Immunovant, Inc. | $39.37 | $8.02B | $0.00 | -$505.61M | $-2.77 | 1.41M |
| 40 | PCVX | Vaxcyte, Inc. | $55.64 | $7.76B | $0.00 | -$946.53M | $-6.91 | 1.62M |
| 41 | IBRX | ImmunityBio, Inc. | $7.40 | $7.60B | $140.98M | -$854.53M | $-0.89 | 11.65M |
| 42 | RYTM | Rhythm Pharmaceuticals, Inc. | $102.66 | $6.98B | $217.16M | -$202.68M | $-3.06 | 913.06K |
| 43 | MIRM | Mirum Pharmaceuticals, Inc. | $114.36 | $6.73B | $569.61M | -$798.84M | $-14.81 | 941.06K |
| 44 | PTCT | PTC Therapeutics, Inc. | $78.45 | $6.47B | $827.11M | -$186.73M | $-2.27 | 2.25M |
| 45 | SRRK | Scholar Rock Holding Corporation | $49.48 | $6.30B | $0.00 | -$408.73M | $-3.58 | 1.58M |
| 46 | CNTA | Centessa Pharmaceuticals plc | $40.50 | $6.22B | $0.00 | -$250.64M | $-1.78 | 1.86M |
| 47 | CGON | CG Oncology, Inc. | $71.12 | $6.01B | $5.07M | -$186.75M | $-2.37 | 1.16M |
| 48 | LGND | Ligand Pharmaceuticals Incorporated | $302.15 | $6.01B | $274.48M | $153.56M | $7.57 | 482.00K |
| 49 | ERAS | Erasca, Inc. | $19.34 | $5.89B | $0.00 | -$277.02M | $-0.96 | 5.63M |
| 50 | XENE | Xenon Pharmaceuticals Inc. | $65.42 | $5.71B | $0.00 | -$383.17M | $-4.72 | 1.65M |
| 51 | BLTE | Belite Bio, Inc | $156.28 | $5.24B | $0.00 | -$77.61M | $-2.31 | 200.17K |
| 52 | TVTX | Travere Therapeutics, Inc. | $56.68 | $5.21B | $536.20M | -$21.42M | $-0.23 | 1.88M |
| 53 | ORKA | Oruka Therapeutics, Inc. | $91.95 | $5.07B | $0.00 | -$116.25M | $-2.37 | 1.56M |
| 54 | DNTH | Dianthus Therapeutics, Inc. | $104.79 | $5.03B | $1.34M | -$11.32M | $-0.28 | 1.39M |
| 55 | CELC | Celcuity Inc. | $88.34 | $4.81B | $0.00 | -$192.89M | $-3.89 | 1.65M |
| 56 | DFTX | Definium Therapeutics, Inc. | $42.93 | $4.67B | $0.00 | -$237.54M | $-2.57 | 3.80M |
| 57 | CRSP | CRISPR Therapeutics AG | $47.53 | $4.57B | $4.10M | -$568.53M | $-6.15 | 1.72M |
| 58 | CAI | Caris Life Sciences, Inc. | $15.65 | $4.42B | $907.29M | $33.98M | $0.14 | 3.14M |
| 59 | DNLI | Denali Therapeutics Inc. | $23.42 | $4.37B | $0.00 | -$508.02M | $-2.88 | 1.98M |
| 60 | LEGN | Legend Biotech Corporation | $23.53 | $4.35B | $1.14B | -$250.18M | $-1.36 | 2.36M |
| 61 | MANE | Veradermics, Incorporated | $115.86 | $4.33B | $0.00 | -$70.00M | $-2.00 | 696.68K |
| 62 | ACAD | ACADIA Pharmaceuticals Inc. | $24.83 | $4.29B | $1.10B | $375.65M | $2.20 | 1.69M |
| 63 | EWTX | Edgewise Therapeutics, Inc. | $39.29 | $4.21B | $0.00 | -$176.01M | $-1.67 | 1.41M |
| 64 | VKTX | Viking Therapeutics, Inc. | $35.39 | $4.09B | $0.00 | -$472.33M | $-4.16 | 2.63M |
| 65 | CPRX | Catalyst Pharmaceuticals, Inc. | $31.49 | $4.00B | $596.96M | $221.32M | $1.74 | 2.00M |
| 66 | DYN | Dyne Therapeutics, Inc. | $23.89 | $3.94B | $0.00 | -$451.71M | $-3.29 | 2.53M |
| 67 | TNGX | Tango Therapeutics, Inc. | $27.45 | $3.94B | $56.99M | -$107.23M | $-0.88 | 4.49M |
| 68 | RCUS | Arcus Biosciences, Inc. | $29.73 | $3.73B | $236.00M | -$369.00M | $-3.31 | 1.43M |
| 69 | NAMS | NewAmsterdam Pharma Company N.V. | $30.55 | $3.70B | $22.41M | -$214.19M | $-1.81 | 1.07M |
| 70 | GPCR | Structure Therapeutics Inc. | $50.80 | $3.68B | $0.00 | -$170.56M | $-2.63 | 800.08K |
| 71 | TLX | Telix Pharmaceuticals Limited | $10.51 | $3.55B | $803.79M | -$7.13M | $-0.02 | 190.92K |
| 72 | ALMS | Alumis Inc. | $28.30 | $3.54B | $8.40M | -$237.41M | $-2.31 | 1.64M |
| 73 | ARQT | Arcutis Biotherapeutics, Inc. | $27.33 | $3.54B | $415.62M | -$2.38M | $-0.02 | 1.69M |
| 74 | RLAY | Relay Therapeutics, Inc. | $19.09 | $3.43B | $10.68M | -$272.70M | $-1.57 | 3.71M |
| 75 | ELVN | Enliven Therapeutics, Inc. | $52.81 | $3.32B | $0.00 | -$98.78M | $-1.69 | 1.88M |
| 76 | IDYA | IDEAYA Biosciences, Inc. | $36.23 | $3.21B | $225.27M | -$140.06M | $-1.58 | 1.26M |
| 77 | MBX | MBX Biosciences, Inc. | $63.57 | $2.96B | $0.00 | -$86.61M | $-2.18 | 1.07M |
| 78 | IRON | Disc Medicine, Inc. | $75.86 | $2.92B | $0.00 | -$241.60M | $-6.71 | 668.98K |
| 79 | RARE | Ultragenyx Pharmaceutical Inc. | $27.02 | $2.72B | $669.71M | -$608.92M | $-6.11 | 2.68M |
| 80 | COGT | Cogent Biosciences, Inc. | $40.24 | $2.71B | $0.00 | -$354.30M | $-3.66 | 2.92M |
| 81 | BEAM | Beam Therapeutics Inc. | $25.91 | $2.68B | $164.01M | -$65.04M | $-0.63 | 2.57M |
| 82 | NRIX | Nurix Therapeutics, Inc. | $23.74 | $2.61B | $71.78M | -$295.28M | $-3.16 | 2.13M |
| 83 | VERA | Vera Therapeutics, Inc. | $36.35 | $2.60B | $0.00 | -$368.95M | $-5.60 | 2.15M |
| 84 | IRD | Opus Genetics, Inc. | $2.92 | $2.54B | $11.98M | -$106.93M | $-0.26 | 1.09M |
| 85 | TARS | Tarsus Pharmaceuticals, Inc. | $58.58 | $2.52B | $535.08M | -$48.27M | $-1.13 | 1.17M |
| 86 | TRVI | Trevi Therapeutics, Inc. | $17.18 | $2.50B | $0.00 | -$45.61M | $-0.32 | 2.83M |
| 87 | IMNM | Immunome, Inc. | $21.99 | $2.49B | $4.01M | -$224.59M | $-2.39 | 1.64M |
| 88 | QURE | uniQure N.V. | $39.43 | $2.47B | $18.09M | -$208.87M | $-3.58 | 2.39M |
| 89 | NUVB | Nuvation Bio Inc. | $6.49 | $2.45B | $143.05M | -$145.99M | $-0.42 | 7.98M |
| 90 | CLDX | Celldex Therapeutics, Inc. | $35.42 | $2.36B | $820.00K | -$283.69M | $-4.27 | 1.22M |
| 91 | VCEL | Vericel Corporation | $45.05 | $2.29B | $292.09M | $21.46M | $0.42 | 647.84K |
| 92 | MLYS | Mineralys Therapeutics, Inc. | $27.00 | $2.24B | $0.00 | -$151.78M | $-2.03 | 1.37M |
| 93 | KOD | Kodiak Sciences Inc. | $41.02 | $2.18B | $0.00 | -$233.09M | $-4.19 | 776.47K |
| 94 | ZLAB | Zai Lab Limited | $19.68 | $2.18B | $453.28M | -$178.12M | $-1.62 | 892.01K |
| 95 | BHVN | Biohaven Ltd. | $14.65 | $2.16B | $0.00 | -$647.68M | $-5.44 | 3.30M |
| 96 | IOVA | Iovance Biotherapeutics, Inc. | $5.13 | $2.15B | $285.61M | -$353.86M | $-0.93 | 15.66M |
| 97 | TSHA | Taysha Gene Therapies, Inc. | $5.83 | $2.14B | $7.47M | -$129.88M | $-0.39 | 3.68M |
| 98 | URGN | UroGen Pharma Ltd. | $42.50 | $2.13B | $140.49M | -$133.22M | $-2.73 | 740.13K |
| 99 | AGIO | Agios Pharmaceuticals, Inc. | $36.28 | $2.13B | $66.05M | -$422.60M | $-7.25 | 1.24M |
| 100 | SLS | SELLAS Life Sciences Group, Inc. | $12.34 | $2.13B | $0.00 | -$29.46M | $-0.22 | 9.73M |
| 101 | HRMY | Harmony Biosciences Holdings, Inc. | $35.80 | $2.10B | $899.11M | $145.62M | $2.48 | 906.89K |
| 102 | AUPH | Aurinia Pharmaceuticals Inc. | $15.24 | $2.10B | $298.30M | $298.21M | $2.16 | 1.70M |
| 103 | MESO | Mesoblast Limited | $16.08 | $2.08B | $17.20M | -$102.14M | $-0.85 | 254.96K |
| 104 | ADMA | ADMA Biologics, Inc. | $8.37 | $2.01B | $509.86M | $165.35M | $0.68 | 3.43M |
| 105 | SION | Sionna Therapeutics, Inc. | $44.06 | $1.98B | $0.00 | -$85.56M | $-1.92 | 544.28K |
| 106 | VRDN | Viridian Therapeutics, Inc. | $19.26 | $1.97B | $70.92M | -$360.59M | $-4.12 | 2.28M |
| 107 | PHVS | Pharvaris N.V. | $33.26 | $1.97B | $0.00 | -$194.29M | $-3.09 | 463.04K |
| 108 | RAPP | Rapport Therapeutics, Inc. | $41.38 | $1.95B | $20.00M | -$107.28M | $-2.56 | 442.11K |
| 109 | SRPT | Sarepta Therapeutics, Inc. | $15.88 | $1.94B | $2.18B | $65.06M | $0.60 | 3.59M |
| 110 | OCUL | Ocular Therapeutix, Inc. | $8.62 | $1.93B | $52.04M | -$290.50M | $-1.45 | 2.84M |
| 111 | TYRA | Tyra Biosciences, Inc. | $30.80 | $1.90B | $0.00 | -$131.10M | $-2.18 | 857.81K |
| 112 | NBTX | Nanobiotix S.A. | $39.55 | $1.89B | $25.59M | -$104.96M | $-2.21 | 106.85K |
| 113 | IMCR | Immunocore Holdings plc | $35.51 | $1.88B | $385.76M | -$19.78M | $-0.39 | 644.80K |
| 114 | SNDX | Syndax Pharmaceuticals, Inc. | $21.21 | $1.87B | $217.17M | -$243.25M | $-2.80 | 2.03M |
| 115 | STOK | Stoke Therapeutics, Inc. | $29.65 | $1.87B | $32.08M | -$169.77M | $-2.85 | 900.10K |
| 116 | LKFT | Lakefront Biotherapeutics NV | $28.12 | $1.85B | $1.19B | $557.08M | $8.45 | 168.01K |
| 117 | INVA | Innoviva, Inc. | $21.20 | $1.80B | $424.12M | $504.34M | $5.94 | 844.25K |
| 118 | FTRE | Fortrea Holdings Inc. | $19.50 | $1.78B | $2.71B | -$446.90M | $-4.85 | 1.35M |
| 119 | GENB | Generate Biomedicines, Inc. | $13.83 | $1.77B | $31.89M | -$203.15M | $-6.16 | 889.82K |
| 120 | PGEN | Precigen, Inc. | $5.54 | $1.73B | $31.59M | -$204.41M | $-0.67 | 4.94M |
| 121 | ZYME | Zymeworks Inc. | $23.12 | $1.73B | $81.26M | -$102.66M | $-1.35 | 599.76K |
| 122 | ZBIO | Zenas BioPharma, Inc. | $30.99 | $1.72B | $0.00 | -$425.15M | $-9.14 | 1.01M |
| 123 | AAPG | Ascentage Pharma Group International | $19.33 | $1.72B | $228.59M | -$241.53M | $-2.93 | 15.14K |
| 124 | ABCL | AbCellera Biologics Inc. | $5.67 | $1.72B | $79.21M | -$136.99M | $-0.46 | 6.60M |
| 125 | NKTR | Nektar Therapeutics | $69.36 | $1.72B | $55.63M | -$158.10M | $-8.10 | 1.07M |
| 126 | GHRS | GH Research PLC | $27.63 | $1.71B | $0.00 | -$56.41M | $-0.91 | 277.86K |
| 127 | BCAX | Bicara Therapeutics Inc. | $27.73 | $1.68B | $0.00 | -$157.31M | $-2.80 | 855.09K |
| 128 | ATAI | AtaiBeckley Inc. | $7.17 | $1.62B | $3.49M | -$663.40M | $-2.78 | 16.60M |
| 129 | PVLA | Palvella Therapeutics, Inc. | $143.21 | $1.61B | $0.00 | -$52.54M | $-4.46 | 302.88K |
| 130 | MPLT | MapLight Therapeutics, Inc. | $35.23 | $1.60B | $0.00 | -$199.48M | $-4.98 | 545.68K |
| 131 | RXRX | Recursion Pharmaceuticals, Inc. | $3.01 | $1.59B | $66.10M | -$559.78M | $-1.17 | 22.76M |
| 132 | ANAB | AnaptysBio, Inc. | $54.91 | $1.58B | $232.39M | -$26.79M | $-0.91 | 754.36K |
| 133 | GLUE | Monte Rosa Therapeutics, Inc. | $23.03 | $1.51B | $42.95M | -$130.01M | $-1.89 | 1.50M |
| 134 | SEPN | Septerna, Inc. | $33.47 | $1.50B | $72.25M | -$36.04M | $-0.81 | 503.02K |
| 135 | MAZE | Maze Therapeutics, Inc. | $27.69 | $1.49B | $20.00M | -$122.54M | $-2.63 | 737.99K |
| 136 | XNCR | Xencor, Inc. | $19.53 | $1.47B | $97.36M | -$172.42M | $-2.31 | 1.05M |
| 137 | SVRA | Savara Inc. | $5.75 | $1.46B | $0.00 | -$129.48M | $-0.57 | 1.99M |
| 138 | AVBP | ArriVent BioPharma, Inc. | $31.54 | $1.42B | $0.00 | -$145.24M | $-3.62 | 607.90K |
| 139 | MLTX | MoonLake Immunotherapeutics | $19.36 | $1.38B | $0.00 | -$257.08M | $-3.92 | 1.35M |
| 140 | VIR | Vir Biotechnology, Inc. | $9.34 | $1.38B | $65.31M | -$442.72M | $-3.14 | 2.11M |
| 141 | XLO | Xilio Therapeutics, Inc. | $8.31 | $1.36B | $53.48M | -$31.30M | $-0.69 | 48.97K |
| 142 | AKTS | Aktis Oncology, Inc. | $24.01 | $1.33B | $6.50M | -$53.93M | $-1.96 | 531.95K |
| 143 | INBX | Inhibrx Biosciences, Inc. | $85.00 | $1.32B | $1.30M | -$130.19M | $-8.39 | 329.72K |
| 144 | NTLA | Intellia Therapeutics, Inc. | $11.10 | $1.32B | $66.09M | -$394.60M | $-3.58 | 5.88M |
| 145 | TRAX | First Tracks Biotherapeutics, Inc. | $37.64 | $1.31B | $0.00 | -$166.09M | — | 843.86K |
| 146 | UNCY | Unicycive Therapeutics, Inc. | $5.46 | $1.31B | $0.00 | -$39.95M | $-0.37 | 2.27M |
| 147 | NVAX | Novavax, Inc. | $7.83 | $1.28B | $596.34M | -$87.83M | $-0.52 | 3.88M |
| 148 | ARDX | Ardelyx, Inc. | $5.13 | $1.26B | $427.68M | -$58.06M | $-0.24 | 4.16M |
| 149 | IMTX | Immatics N.V. | $9.29 | $1.25B | $42.51M | -$244.37M | $-1.94 | 357.60K |
| 150 | ABSI | Absci Corporation | $8.07 | $1.23B | $1.84M | -$118.44M | $-0.82 | 6.66M |
| 151 | CRVS | Corvus Pharmaceuticals, Inc. | $13.68 | $1.23B | $0.00 | -$44.17M | $-0.53 | 1.31M |
| 152 | OLMA | Olema Pharmaceuticals, Inc. | $11.74 | $1.21B | $0.00 | -$185.15M | $-2.03 | 1.69M |
| 153 | MNKD | MannKind Corporation | $3.89 | $1.20B | $360.78M | -$23.91M | $-0.08 | 4.97M |
| 154 | DBVT | DBV Technologies S.A. | $13.86 | $1.19B | $2.37M | -$167.32M | $-2.35 | 308.62K |
| 155 | CBUS | Cibus, Inc. | $1.78 | $1.16B | $4.29M | -$101.42M | $-0.51 | 423.94K |
| 156 | WVE | Wave Life Sciences Ltd. | $5.78 | $1.16B | $71.80M | -$183.59M | $-1.03 | 2.87M |
| 157 | ORIC | ORIC Pharmaceuticals, Inc. | $10.89 | $1.15B | $0.00 | -$135.21M | $-1.46 | 1.66M |
| 158 | CAPR | Capricor Therapeutics, Inc. | $19.83 | $1.14B | $0.00 | -$114.59M | $-2.32 | 1.65M |
| 159 | JBIO | Jade Biosciences, Inc. | $19.62 | $1.13B | $0.00 | -$129.61M | $-2.96 | 1.23M |
| 160 | EYPT | EyePoint, Inc. | $12.47 | $1.07B | $7.62M | -$271.60M | $-3.51 | 1.48M |
| 161 | DRTS | Alpha Tau Medical Ltd. | $13.24 | $1.07B | $0.00 | -$42.63M | $-0.53 | 778.25K |
| 162 | MRVI | Maravai LifeSciences Holdings, Inc. | $7.05 | $1.03B | $204.73M | -$104.56M | $-0.72 | 3.22M |
| 163 | ANNX | Annexon, Inc. | $5.30 | $1.03B | $0.00 | -$196.48M | $-1.18 | 4.55M |
| 164 | CGEM | Cullinan Therapeutics, Inc. | $17.28 | $1.02B | $0.00 | -$221.04M | $-3.64 | 1.09M |
| 165 | JANX | Janux Therapeutics, Inc. | $15.72 | $985.11M | $21.61M | -$114.48M | $-1.84 | 1.28M |
| 166 | MGTX | MeiraGTx Holdings plc | $12.10 | $983.74M | $79.76M | -$120.53M | $-1.49 | 1.06M |
| 167 | LBRX | LB Pharmaceuticals Inc | $34.62 | $977.73M | $0.00 | -$39.17M | $-2.62 | 334.64K |
| 168 | GERN | Geron Corporation | $1.45 | $970.59M | $196.12M | -$67.31M | $-0.10 | 12.37M |
| 169 | REPL | Replimune Group, Inc. | $10.46 | $964.28M | $0.00 | -$314.85M | $-3.54 | 3.12M |
| 170 | FBIO | Fortress Biotech, Inc. | $3.43 | $957.03M | $65.83M | $108.35M | $1.17 | 577.69K |
| 171 | PHAT | Phathom Pharmaceuticals, Inc. | $11.60 | $951.79M | $204.89M | -$157.30M | $-2.09 | 1.05M |
| 172 | KURA | Kura Oncology, Inc. | $10.45 | $925.97M | $71.64M | -$294.57M | $-3.35 | 1.61M |
| 173 | PHAR | Pharming Group N.V. | $13.17 | $923.75M | $106.76B | $5.31B | $77.44 | 5.79K |
| 174 | LXRX | Lexicon Pharmaceuticals, Inc. | $2.30 | $920.55M | $69.64M | -$26.09M | $-0.07 | 4.08M |
| 175 | CRIS | Curis, Inc. | $4.67 | $904.27M | $7.06M | -$21.16M | $-0.36 | 343.32K |
| 176 | MNPR | Monopar Therapeutics Inc. | $105.70 | $902.15M | $0.00 | -$14.98M | $-2.04 | 204.04K |
| 177 | SANA | Sana Biotechnology, Inc. | $3.21 | $888.71M | $0.00 | -$241.99M | $-0.94 | 3.27M |
| 178 | ANRO | Alto Neuroscience, Inc. | $26.85 | $883.18M | $0.00 | -$74.31M | $-2.50 | 635.63K |
| 179 | SLDB | Solid Biosciences Inc. | $7.98 | $876.30M | $0.00 | -$191.78M | $-1.95 | 2.32M |
| 180 | ABUS | Arbutus Biopharma Corporation | $4.47 | $872.61M | $191.44M | $160.72M | $0.83 | 2.66M |
| 181 | CLYM | Climb Bio, Inc. | $12.76 | $870.33M | $0.00 | -$52.79M | $-0.84 | 1.37M |
| 182 | TBPH | Theravance Biopharma, Inc. | $16.86 | $864.56M | $109.78M | $114.54M | $2.21 | 813.61K |
| 183 | IVA | Inventiva S.A. | $4.51 | $842.48M | $15.59M | -$612.08M | $-2.88 | 1.37M |
| 184 | STTK | Shattuck Labs, Inc. | $7.09 | $795.74M | $0.00 | -$49.87M | $-0.59 | 1.69M |
| 185 | NGNE | Neurogene Inc. | $35.57 | $793.41M | $0.00 | -$98.64M | $-4.93 | 277.42K |
| 186 | ZVRA | Zevra Therapeutics, Inc. | $12.52 | $754.09M | $122.29M | $124.22M | $2.16 | 1.45M |
| 187 | CRMD | CorMedix Inc. | $8.05 | $748.53M | $400.05M | $181.01M | $2.10 | 1.29M |
| 188 | RIGL | Rigel Pharmaceuticals, Inc. | $36.82 | $724.84M | $299.77M | $364.23M | $19.21 | 390.24K |
| 189 | DSGN | Design Therapeutics, Inc. | $11.63 | $714.48M | $0.00 | -$69.71M | $-1.20 | 864.68K |
| 190 | FDMT | 4D Molecular Therapeutics, Inc. | $10.38 | $706.51M | $88.24M | -$160.90M | $-2.70 | 988.22K |
| 191 | ACRS | Aclaris Therapeutics, Inc. | $5.48 | $705.88M | $8.37M | -$69.66M | $-0.56 | 1.96M |
| 192 | INO | Inovio Pharmaceuticals, Inc. | $1.02 | $704.84M | $0.00 | -$84.93M | $-0.27 | 1.41M |
| 193 | XOMA | XOMA Royalty Corporation | $40.17 | $699.64M | $27.41M | $31.51M | $1.76 | 310.78K |
| 194 | DRUG | Bright Minds Biosciences Inc. | $71.29 | $683.66M | $0.00 | -$19.55M | $-2.47 | 330.28K |
| 195 | OCS | Oculis Holding AG | $11.44 | $673.88M | $617.95K | -$116.55M | $-2.12 | 445.42K |
| 196 | TENX | Tenax Therapeutics, Inc. | $14.64 | $662.11M | $0.00 | -$36.21M | $-0.88 | 1.36M |
| 197 | OMER | Omeros Corporation | $10.28 | $652.88M | $9.89M | $198.04M | $2.81 | 2.03M |
| 198 | CADL | Candel Therapeutics, Inc. | $9.86 | $614.89M | $0.00 | -$54.42M | $-0.97 | 1.85M |
| 199 | MDXG | MiMedx Group, Inc. | $4.13 | $613.08M | $389.42M | $30.70M | $0.21 | 1.23M |
| 200 | VSTM | Verastem, Inc. | $6.18 | $612.73M | $49.59M | -$193.96M | $-2.35 | 2.89M |
| 201 | SPRY | ARS Pharmaceuticals, Inc. | $6.00 | $595.78M | $98.99M | -$197.98M | $-2.00 | 2.09M |
| 202 | ZURA | Zura Bio Limited | $5.29 | $593.66M | $0.00 | -$75.43M | $-0.76 | 1.33M |
| 203 | TECX | Tectonic Therapeutic, Inc. | $31.61 | $593.29M | $0.00 | -$83.49M | $-4.46 | 184.02K |
| 204 | CTMX | CytomX Therapeutics, Inc. | $3.33 | $590.32M | $35.54M | -$59.14M | $-0.37 | 5.12M |
| 205 | BNTC | Benitec Biopharma Inc. | $11.44 | $564.98M | $0.00 | -$48.88M | $-1.10 | 134.39K |
| 206 | RZLT | Rezolute, Inc. | $5.31 | $552.45M | $0.00 | -$81.48M | $-0.80 | 2.04M |
| 207 | GYRE | Crescent Biopharma, Inc. | $6.01 | $548.98M | $117.05M | -$6.29M | $-0.06 | 100.51K |
| 208 | SLN | Silence Therapeutics plc | $11.45 | $540.83M | $838.29K | -$75.01M | $-1.59 | 570.88K |
| 209 | RGNX | REGENXBIO Inc. | $10.25 | $537.39M | $87.82M | -$290.01M | $-5.59 | 2.69M |
| 210 | CTNM | Contineum Therapeutics, Inc. | $14.37 | $536.56M | $0.00 | -$58.44M | $-1.91 | 421.21K |
| 211 | PRME | Prime Medicine, Inc. | $2.97 | $525.98M | $4.03M | -$198.37M | $-1.29 | 3.92M |
| 212 | EIKN | Eikon Therapeutics, Inc. | $9.62 | $520.81M | $0.00 | -$324.25M | $-112.04 | 413.94K |
| 213 | ARVN | Arvinas, Inc. | $8.12 | $519.68M | $89.40M | -$221.30M | $-3.22 | 738.36K |
| 214 | CBIO | Crescent Biopharma, Inc. | $17.03 | $517.68M | $11.88M | -$162.08M | $-9.14 | 425.29K |
| 215 | XFOR | X4 Pharmaceuticals, Inc. | $3.99 | $503.89M | $9.01M | -$99.72M | $-1.39 | 923.83K |
| 216 | AURA | Aura Biosciences, Inc. | $7.20 | $485.62M | $0.00 | -$112.39M | $-1.79 | 655.69K |
| 217 | DNA | Ginkgo Bioworks Holdings, Inc. | $7.93 | $472.34M | $141.31M | -$304.39M | $-5.36 | 1.06M |
| 218 | NVCT | Nuvectis Pharma, Inc. | $20.15 | $471.80M | $0.00 | -$29.59M | $-1.33 | 472.16K |
| 219 | PRTA | Prothena Corporation plc | $8.53 | $461.55M | $57.94M | -$151.18M | $-2.80 | 600.68K |
| 220 | CCCC | C4 Therapeutics, Inc. | $3.65 | $460.17M | $34.86M | -$103.80M | $-1.07 | 3.66M |
| 221 | RLMD | Relmada Therapeutics, Inc. | $5.20 | $450.30M | $0.00 | -$58.88M | $-1.06 | 2.34M |
| 222 | KYTX | Kyverna Therapeutics, Inc. | $7.29 | $440.57M | $0.00 | -$156.40M | $-3.22 | 1.26M |
| 223 | ALLO | Allogene Therapeutics, Inc. | $1.82 | $437.33M | $0.00 | -$173.76M | $-0.77 | 9.19M |
| 224 | IMUX | Immunic, Inc. | $14.28 | $430.35M | $0.00 | -$104.29M | $-5.33 | 181.44K |
| 225 | CNTN | Canton Strategic Holdings, Inc. | $2.06 | $427.87M | $0.00 | -$80.72M | $-1.30 | 1.15M |
| 226 | ASMB | Assembly Biosciences, Inc. | $25.22 | $426.22M | $71.10M | -$6.38M | $-0.53 | 241.96K |
| 227 | PALI | Palisade Bio, Inc. | $2.02 | $423.52M | $0.00 | -$24.15M | $-0.35 | 4.15M |
| 228 | ANL | Adlai Nortye Ltd. | $13.22 | $422.70M | $6.49M | -$54.06M | $-6.97 | 208.58K |
| 229 | ELDN | Eledon Pharmaceuticals, Inc. | $3.74 | $420.47M | $0.00 | -$78.15M | $-0.91 | 1.58M |
| 230 | SGP | SpyGlass Pharma, Inc. | $20.88 | $416.09M | $0.00 | -$39.87M | $-17.98 | 159.77K |
| 231 | VALN | Valneva SE | $4.78 | $411.29M | $178.18M | -$157.32M | $-1.88 | 25.33K |
| 232 | PBYI | Puma Biotechnology, Inc. | $8.01 | $407.27M | $227.18M | $24.38M | $0.48 | 366.95K |
| 233 | OCGN | Ocugen, Inc. | $1.27 | $406.94M | $4.46M | -$71.67M | $-0.23 | 8.37M |
| 234 | AUTL | Autolus Therapeutics plc | $1.52 | $404.54M | $92.62M | -$288.96M | $-1.09 | 1.10M |
| 235 | CMPX | Compass Therapeutics, Inc. | $2.12 | $395.17M | $0.00 | -$68.17M | $-0.40 | 3.00M |
| 236 | KROS | Keros Therapeutics, Inc. | $10.14 | $383.89M | $33.18M | -$85.14M | $-2.17 | 291.45K |
| 237 | LXEO | Lexeo Therapeutics, Inc. | $4.71 | $382.38M | $0.00 | -$87.50M | $-1.34 | 1.07M |
| 238 | EVMN | Evommune, Inc. | $11.32 | $381.15M | $10.00M | -$75.99M | $-2.42 | 1.16M |
| 239 | AVIR | Atea Pharmaceuticals, Inc. | $4.75 | $376.19M | $0.00 | -$169.52M | $-2.12 | 328.66K |
| 240 | RCKT | Rocket Pharmaceuticals, Inc. | $3.28 | $367.80M | $0.00 | -$209.38M | $-1.88 | 2.65M |
| 241 | DMAC | DiaMedica Therapeutics Inc. | $6.82 | $366.87M | $0.00 | -$35.10M | $-0.73 | 238.04K |
| 242 | ABEO | Abeona Therapeutics Inc. | $6.38 | $361.24M | $14.54M | $66.14M | $1.09 | 1.43M |
| 243 | FENC | Fennec Pharmaceuticals Inc. | $10.15 | $360.81M | $50.96M | -$8.38M | $-0.27 | 236.15K |
| 244 | EPRX | Eupraxia Pharmaceuticals Inc. | $6.30 | $357.29M | $0.00 | -$44.26M | $-0.98 | 362.56K |
| 245 | AVTX | Avalo Therapeutics, Inc. | $17.76 | $357.10M | $59.00K | -$84.74M | $-5.34 | 1.71M |
| 246 | ALT | Altimmune, Inc. | $2.84 | $353.47M | $36.00K | -$91.08M | $-0.92 | 4.17M |
| 247 | FHTX | Foghorn Therapeutics Inc. | $5.07 | $352.57M | $28.22M | -$75.32M | $-1.17 | 341.24K |
| 248 | UPB | Upstream Bio, Inc. | $6.40 | $347.73M | $3.32M | -$156.76M | $-2.90 | 605.42K |
| 249 | LRMR | Larimar Therapeutics, Inc. | $4.01 | $341.58M | $0.00 | -$166.00M | $-2.12 | 2.65M |
| 250 | IMMX | Immix Biopharma, Inc. | $8.80 | $336.92M | $0.00 | -$34.98M | $-1.01 | 2.14M |
| 251 | ACHV | Achieve Life Sciences, Inc. | $6.17 | $329.37M | $0.00 | -$51.99M | $-1.08 | 2.39M |
| 252 | HELP | Cybin Inc. | $7.73 | $328.69M | $0.00 | -$131.58M | $-4.78 | 1.65M |
| 253 | PRLD | Prelude Therapeutics Incorporated | $3.93 | $324.30M | $16.72M | -$77.80M | $-1.05 | 469.48K |
| 254 | VNDA | Vanda Pharmaceuticals Inc. | $5.36 | $318.71M | $217.78M | -$239.55M | $-4.05 | 914.99K |
| 255 | ZNTL | Zentalis Pharmaceuticals, Inc. | $4.45 | $312.67M | $0.00 | -$124.13M | $-1.74 | 1.40M |
| 256 | CABA | Cabaletta Bio, Inc. | $2.72 | $304.71M | $0.00 | -$175.43M | $-1.85 | 5.61M |
| 257 | FATE | Fate Therapeutics, Inc. | $2.52 | $302.48M | $6.32M | -$129.91M | $-1.09 | 4.08M |
| 258 | BCYC | Bicycle Therapeutics plc | $4.16 | $289.88M | $63.50M | -$219.03M | $-3.16 | 538.08K |
| 259 | FULC | Fulcrum Therapeutics, Inc. | $3.76 | $286.57M | $0.00 | -$76.12M | $-1.15 | 2.69M |
| 260 | NMRA | Neumora Therapeutics, Inc. | $1.56 | $280.60M | $0.00 | -$222.39M | $-1.33 | 3.16M |
| 261 | LYEL | Lyell Immunopharma, Inc. | $12.78 | $279.58M | $31.00K | -$246.41M | $-12.94 | 224.76K |
| 262 | LCTX | Lineage Cell Therapeutics, Inc. | $1.07 | $279.46M | $14.78M | -$64.21M | $-0.27 | 1.75M |
| 263 | CLLS | Cellectis S.A. | $2.77 | $278.46M | $69.56M | -$67.29M | $-0.67 | 28.90K |
| 264 | ENTA | Enanta Pharmaceuticals, Inc. | $12.95 | $276.87M | $69.21M | -$61.98M | $-2.67 | 228.00K |
| 265 | BBOT | BridgeBio Oncology Therapeutics, Inc. | $8.72 | $271.58M | $0.00 | -$154.09M | $-3.33 | 489.71K |
| 266 | NAGE | Niagen Bioscience, Inc. | $3.19 | $269.77M | $130.42M | $18.64M | $0.22 | 721.78K |
| 267 | EDIT | Editas Medicine, Inc. | $2.73 | $267.21M | $38.69M | -$108.95M | $-1.18 | 2.53M |
| 268 | VTVT | vTv Therapeutics Inc. | $31.66 | $266.69M | $36.84M | $2.25M | $0.29 | 69.13K |
| 269 | OABI | OmniAb, Inc. | $2.04 | $261.80M | $28.91M | -$54.28M | $-0.46 | 571.93K |
| 270 | EQ | Equillium, Inc. | $2.69 | $258.99M | $0.00 | -$19.05M | $-0.26 | 816.07K |
| 271 | MGNX | MacroGenics, Inc. | $4.01 | $254.43M | $157.08M | -$70.36M | $-1.11 | 1.15M |
| 272 | TRDA | Entrada Therapeutics, Inc. | $6.05 | $253.11M | $5.74M | -$166.12M | $-4.00 | 379.49K |
| 273 | ARTV | Artiva Biotherapeutics, Inc. | $10.13 | $249.99M | $0.00 | -$87.07M | $-3.55 | 605.67K |
| 274 | WHWK | Whitehawk Therapeutics, Inc. | $3.83 | $237.03M | $7.14M | -$20.60M | $-0.35 | 557.29K |
| 275 | AGEN | Agenus Inc. | $6.19 | $236.98M | $123.87M | $64.61M | $1.92 | 7.39M |
| 276 | SRZN | Surrozen, Inc. | $21.16 | $231.68M | $7.49M | -$342.56M | $-36.87 | 173.89K |
| 277 | IKT | Inhibikase Therapeutics, Inc. | $2.33 | $229.06M | $0.00 | -$50.96M | $-0.54 | 1.01M |
| 278 | SGMT | Sagimet Biosciences Inc. | $7.01 | $228.24M | $0.00 | -$43.51M | $-1.34 | 1.27M |
| 279 | SLGL | Sol-Gel Technologies Ltd. | $80.55 | $224.40M | $19.39M | -$6.13M | $-2.20 | 35.56K |
| 280 | NAUT | Nautilus Biotechnology, Inc. | $1.77 | $224.14M | $0.00 | -$57.09M | $-0.45 | 978.45K |
| 281 | ACIU | AC Immune SA | $2.24 | $221.03M | $4.54M | -$81.19M | $-0.81 | 262.26K |
| 282 | AVXL | Anavex Life Sciences Corp. | $2.48 | $220.79M | $0.00 | -$39.95M | $-0.46 | 1.34M |
| 283 | GALT | Galectin Therapeutics Inc. | $3.45 | $220.47M | $0.00 | -$24.23M | $-0.37 | 991.22K |
| 284 | CGEN | Compugen Ltd. | $2.34 | $219.53M | $72.76M | $49.70M | $0.53 | 275.22K |
| 285 | QTTB | Q32 Bio Inc. | $15.38 | $216.79M | $53.74M | $33.24M | $2.60 | 1.79M |
| 286 | PROK | ProKidney Corp. | $1.52 | $215.73M | $889.00K | -$74.84M | $-0.55 | 1.35M |
| 287 | RNAC | Cartesian Therapeutics, Inc. | $7.92 | $212.69M | $1.77M | -$151.77M | $-5.77 | 280.72K |
| 288 | ENLV | Enlivex Ltd. | $4.36 | $211.46M | $0.00 | $1.24B | $41.23 | 57.42K |
| 289 | RNA | Atrium Therapeutics, Inc. | $11.91 | $203.73M | $36.82M | -$396.46M | $-5.26 | 217.25K |
| 290 | MENS | Jyong Biotech Ltd. | $2.71 | $197.86M | $0.00 | -$4.67M | $-0.06 | 131.15K |
| 291 | PLX | Protalix BioTherapeutics, Inc. | $2.37 | $196.83M | $76.38M | $15.33M | $0.19 | 631.29K |
| 292 | NERV | Minerva Neurosciences, Inc. | $4.45 | $195.35M | $0.00 | -$415.07M | $-23.67 | 308.47K |
| 293 | CHRS | Coherus Oncology, Inc. | $1.43 | $195.05M | $46.88M | $195.64M | $1.60 | 907.73K |
| 294 | IMRX | Immuneering Corporation | $4.39 | $193.21M | $0.00 | -$54.44M | $-1.33 | 1.36M |
| 295 | GLSI | Greenwich LifeSciences, Inc. | $13.19 | $192.12M | $0.00 | -$21.76M | $-1.58 | 169.31K |
| 296 | SABS | SAB Biotherapeutics, Inc. | $3.58 | $191.74M | $0.00 | -$398.43K | $-0.01 | 971.74K |
| 297 | ARMP | Armata Pharmaceuticals, Inc. | $5.22 | $190.69M | $2.96M | -$282.61M | $-7.78 | 211.49K |
| 298 | IVVD | Invivyd, Inc. | $0.61 | $188.65M | $55.87M | -$77.60M | $-0.40 | 5.72M |
| 299 | PRQR | ProQR Therapeutics N.V. | $1.79 | $188.60M | $15.33M | -$52.10M | $-0.49 | 1.37M |
| 300 | ADCT | ADC Therapeutics SA | $1.22 | $188.05M | $79.17M | -$136.99M | $-0.99 | 1.44M |
| 301 | IPSC | Century Therapeutics, Inc. | $2.17 | $187.83M | $0.00 | -$107.78M | $-1.25 | 1.71M |
| 302 | VYGR | Voyager Therapeutics, Inc. | $3.09 | $183.84M | $36.49M | -$116.64M | $-1.98 | 730.19K |
| 303 | MDWD | MediWound Ltd. | $14.27 | $183.71M | $14.48M | -$26.11M | $-2.20 | 82.47K |
| 304 | CDXS | Codexis, Inc. | $1.99 | $180.63M | $78.09M | -$31.99M | $-0.36 | 816.95K |
| 305 | ACOG | Alpha Cognition Inc. | $8.23 | $180.45M | $10.83M | -$25.14M | $-1.31 | 75.52K |
| 306 | OVID | Ovid Therapeutics Inc. | $2.40 | $176.97M | $7.12M | -$24.17M | $-0.32 | 3.20M |
| 307 | ORMP | Oramed Pharmaceuticals Inc. | $4.16 | $176.46M | $0.00 | $110.00M | $2.59 | 403.48K |
| 308 | KPTI | Karyopharm Therapeutics Inc. | $7.09 | $175.23M | $151.12M | -$194.97M | $-13.00 | 576.98K |
| 309 | CAMP | Camp4 Therapeutics Corporation | $3.01 | $174.35M | $3.93M | -$86.30M | $-2.20 | 302.18K |
| 310 | TARA | Protara Therapeutics, Inc. | $4.04 | $173.06M | $0.00 | -$63.31M | $-1.46 | 699.06K |
| 311 | NKTX | Nkarta, Inc. | $2.30 | $170.79M | $0.00 | -$99.93M | $-1.35 | 762.28K |
| 312 | PYXS | Pyxis Oncology, Inc. | $2.68 | $170.10M | $13.86M | -$81.73M | $-1.31 | 1.26M |
| 313 | ANTX | AN2 Therapeutics, Inc. | $4.92 | $167.57M | $0.00 | -$34.55M | $-1.11 | 371.65K |
| 314 | IBIO | iBio, Inc. | $1.40 | $167.44M | $300.00K | -$27.38M | $-0.38 | 949.86K |
| 315 | ALEC | Alector, Inc. | $1.49 | $164.78M | $18.42M | -$125.39M | $-1.20 | 786.06K |
| 316 | ARCT | Arcturus Therapeutics Holdings Inc. | $5.79 | $164.56M | $46.15M | -$78.67M | $-2.86 | 512.45K |
| 317 | RANI | Rani Therapeutics Holdings, Inc. | $0.89 | $160.20M | $3.17M | -$29.44M | $-0.29 | 893.20K |
| 318 | CUE | Cue Biopharma, Inc. | $33.09 | $159.08M | $32.73M | -$19.52M | $-5.19 | 119.58K |
| 319 | LENZ | LENZ Therapeutics, Inc. | $5.05 | $158.33M | $20.99M | -$109.00M | $-3.66 | 961.34K |
| 320 | IPHA | Innate Pharma S.A. | $1.76 | $157.68M | $17.56M | -$112.20M | $-1.32 | 25.61K |
| 321 | MIST | Milestone Pharmaceuticals Inc. | $1.20 | $156.34M | $1.78M | -$68.36M | $-0.79 | 1.25M |
| 322 | CRBU | Caribou Biosciences, Inc. | $1.63 | $156.25M | $11.20M | -$133.22M | $-1.41 | 2.37M |
| 323 | MOLN | Molecular Partners AG | $3.97 | $148.89M | $0.00 | -$75.60M | $-2.02 | 7.41K |
| 324 | ICU | SeaStar Medical Holding Corporation | $3.77 | $147.88M | $1.44M | -$11.90M | $-1.02 | 102.51K |
| 325 | TNXP | Tonix Pharmaceuticals Holding Corp. | $10.62 | $145.57M | $17.56M | -$147.39M | $-14.12 | 578.96K |
| 326 | OBIO | Orchestra BioMed Holdings, Inc. | $3.64 | $139.75M | $32.72M | -$54.64M | $-1.31 | 434.02K |
| 327 | AARD | Aardvark Therapeutics, Inc. | $6.39 | $139.40M | $0.00 | -$87.47M | $-4.02 | 363.72K |
| 328 | ABOS | Acumen Pharmaceuticals, Inc. | $2.17 | $137.19M | $0.00 | -$113.28M | $-1.85 | 596.76K |
| 329 | YDES | YD Bio Limited | $2.04 | $136.11M | $392.81K | -$11.98M | $-0.18 | 249.84K |
| 330 | KRRO | Korro Bio, Inc. | $11.53 | $133.73M | $3.84M | -$113.50M | $-11.41 | 263.15K |
| 331 | NRXP | NRx Pharmaceuticals, Inc. | $4.11 | $132.86M | $2.29M | -$24.54M | $-0.94 | 835.76K |
| 332 | ENGN | enGene Therapeutics Inc. | $1.89 | $131.78M | $0.00 | -$66.40M | $-1.11 | 1.07M |
| 333 | TTRX | Turn Therapeutics Inc. | $9.48 | $130.29M | $0.00 | -$3.84M | $-0.13 | 100.69K |
| 334 | ADAG | Adagene Inc. | $3.37 | $127.26M | $7.80M | -$51.08M | $-1.38 | 302.88K |
| 335 | HUMA | Humacyte, Inc. | $0.64 | $126.34M | $2.02M | -$97.59M | $-0.58 | 14.74M |
| 336 | ANIX | Anixa Biosciences, Inc. | $3.75 | $125.97M | $0.00 | -$10.07M | $-0.31 | 302.84K |
| 337 | IFRX | InflaRx N.V. | $1.73 | $125.07M | $33.43K | -$48.91M | $-0.71 | 1.23M |
| 338 | CRBP | Corbus Pharmaceuticals Holdings, Inc. | $9.32 | $124.12M | $0.00 | -$84.53M | $-6.61 | 414.03K |
| 339 | CNTB | Connect Biopharma Holdings Limited | $2.20 | $122.45M | $762.00K | -$60.32M | $-1.08 | 558.24K |
| 340 | NGEN | NervGen Pharma Corp. | $1.68 | $121.15M | $0.00 | -$45.82M | $-0.61 | 859.60K |
| 341 | TNYA | Tenaya Therapeutics, Inc. | $0.77 | $118.26M | $225.00K | -$83.00M | $-0.51 | 2.41M |
| 342 | ATRA | Atara Biotherapeutics, Inc. | $8.17 | $115.04M | $23.14M | -$9.47M | $-0.70 | 81.23K |
| 343 | SEER | Seer, Inc. | $2.05 | $114.79M | $14.77M | -$70.49M | $-1.25 | 1.31M |
| 344 | INTS | Intensity Therapeutics, Inc. | $4.49 | $113.72M | $0.00 | -$10.69M | $-1.42 | 52.23K |
| 345 | VANI | Vivani Medical, Inc. | $1.39 | $112.96M | $0.00 | -$27.09M | $-0.41 | 766.46K |
| 346 | TCRX | TScan Therapeutics, Inc. | $0.85 | $109.96M | $9.14M | -$124.31M | $-0.96 | 806.92K |
| 347 | ALXO | ALX Oncology Holdings Inc. | $2.02 | $109.65M | $0.00 | -$88.87M | $-1.65 | 1.65M |
| 348 | BDTX | Black Diamond Therapeutics, Inc. | $1.84 | $105.31M | $0.00 | -$43.21M | $-0.76 | 1.76M |
| 349 | HURA | TuHURA Biosciences, Inc. | $2.15 | $103.04M | $0.00 | -$28.17M | $-0.65 | 590.91K |
| 350 | ENTX | Entera Bio Ltd. | $2.13 | $101.72M | $0.00 | -$12.38M | $-0.26 | 2.02M |
| 351 | ICCC | ImmuCell Corporation | $11.16 | $100.95M | $29.93M | -$545.40K | $-0.06 | 32.04K |
| 352 | GNLX | Genelux Corporation | $2.96 | $96.20M | $8.00K | -$31.78M | $-0.87 | 182.16K |
| 353 | PLYX | Polaryx Therapeutics, Inc. | $2.11 | $95.84M | $0.00 | -$8.98M | $-0.19 | 95.42K |
| 354 | ONCY | Oncolytics Biotech Inc. | $0.85 | $95.26M | $0.00 | -$29.82M | $-0.30 | 1.51M |
| 355 | PTHS | Pelthos Therapeutics Inc. | $28.40 | $94.05M | $27.70M | -$51.59M | $-20.29 | 35.87K |
| 356 | DTIL | Precision BioSciences, Inc. | $7.33 | $94.02M | $45.07M | $190.00K | $0.01 | 546.18K |
| 357 | ALDX | Aldeyra Therapeutics, Inc. | $1.55 | $93.49M | $0.00 | -$27.37M | $-0.45 | 1.78M |
| 358 | RLYB | Rallybio Corporation | $16.39 | $93.24M | $858.00K | -$7.82M | $-1.41 | 48.13K |
| 359 | KLRS | Kalaris Therapeutics, Inc. | $3.92 | $93.00M | $0.00 | -$44.10M | $-2.10 | 458.60K |
| 360 | QNCX | Quince Therapeutics, Inc. | $18.28 | $91.58M | $0.00 | -$33.04M | $-6.58 | 31.14K |
| 361 | BMEA | Biomea Fusion, Inc. | $1.26 | $91.10M | $0.00 | -$44.95M | $-0.73 | 855.73K |
| 362 | ACET | Adicet Bio, Inc. | $8.42 | $90.47M | $0.00 | -$108.83M | $-13.40 | 90.56K |
| 363 | NBP | NovaBridge Biosciences | $1.77 | $88.79M | $0.00 | -$47.52M | $-0.54 | 635.48K |
| 364 | PEPG | PepGen Inc. | $2.10 | $88.67M | $0.00 | -$77.22M | $-2.04 | 968.10K |
| 365 | HRTX | Heron Therapeutics, Inc. | $0.46 | $87.05M | $150.71M | -$30.94M | $-0.18 | 3.33M |
| 366 | CGTX | Cognition Therapeutics, Inc. | $0.96 | $85.64M | $0.00 | -$19.58M | $-0.24 | 1.92M |
| 367 | CSBR | Champions Oncology, Inc. | $6.00 | $83.32M | $57.94M | -$2.25M | $-0.16 | 7.40K |
| 368 | PMN | ProMIS Neurosciences, Inc. | $12.61 | $82.32M | $0.00 | -$40.62M | $-13.97 | 73.77K |
| 369 | ATHE | Alterity Therapeutics Limited | $4.69 | $79.57M | $5.28M | -$23.90M | $-1.96 | 24.27K |
| 370 | GANX | Gain Therapeutics, Inc. | $1.82 | $76.86M | $0.00 | -$21.24M | $-0.60 | 1.10M |
| 371 | NRXS | NeurAxis, Inc. | $7.01 | $76.75M | $4.28M | -$7.49M | $-0.78 | 77.90K |
| 372 | COYA | Coya Therapeutics, Inc. | $4.38 | $73.28M | $7.94M | -$21.13M | $-1.26 | 252.98K |
| 373 | PMVP | PMV Pharmaceuticals, Inc. | $1.33 | $70.93M | $0.00 | -$78.34M | $-1.48 | 305.23K |
| 374 | NTHI | NeOnc Technologies Holdings, Inc. | $3.63 | $69.74M | $0.00 | -$48.48M | $-2.34 | 107.32K |
| 375 | XBIT | XBiotech Inc. | $2.28 | $69.51M | $0.00 | -$40.16M | $-1.32 | 39.68K |
| 376 | PYPD | PolyPid Ltd. | $4.24 | $69.33M | $0.00 | -$34.17M | $-2.10 | 279.22K |
| 377 | PLRX | Pliant Therapeutics, Inc. | $1.08 | $66.75M | $0.00 | -$113.22M | $-1.84 | 603.66K |
| 378 | SPRO | Spero Therapeutics, Inc. | $1.16 | $66.45M | $54.77M | $15.23M | $0.27 | 2.03M |
| 379 | ACRV | Acrivon Therapeutics, Inc. | $1.67 | $64.67M | $0.00 | -$77.27M | $-2.00 | 430.28K |
| 380 | MNOV | MediciNova, Inc. | $1.31 | $64.48M | $596.64K | -$11.72M | $-0.24 | 66.63K |
| 381 | APM | Aptorum Group Limited | $8.57 | $63.00M | $431.38K | -$1.36M | $-0.19 | 181.87K |
| 382 | IMA | ImageneBio, Inc. | $5.57 | $62.45M | $0.00 | -$45.07M | $-5.16 | 11.63K |
| 383 | SPRB | Spruce Biosciences, Inc. | $44.99 | $61.73M | $0.00 | -$37.19M | $-45.16 | 80.07K |
| 384 | VRCA | Verrica Pharmaceuticals Inc. | $5.44 | $57.95M | $37.16M | -$17.83M | $-1.77 | 37.33K |
| 385 | IMMP | Immutep Limited | $0.39 | $57.71M | $8.94M | -$89.28M | $-0.64 | 378.85K |
| 386 | OKUR | OnKure Therapeutics, Inc. | $4.22 | $57.71M | $0.00 | -$58.75M | $-4.33 | 364.09K |
| 387 | GUTS | Fractyl Health, Inc. | $0.76 | $57.37M | $0.00 | -$108.00M | $-1.26 | 1.90M |
| 388 | ELTX | Elicio Therapeutics, Inc. | $3.15 | $57.37M | $0.00 | -$40.19M | $-2.42 | 3.32M |
| 389 | CRDF | Cardiff Oncology, Inc. | $0.84 | $57.28M | $525.00K | -$44.76M | $-0.67 | 1.72M |
| 390 | BOLD | Boundless Bio, Inc. | $2.52 | $56.47M | $0.00 | -$55.99M | $-2.50 | 2.47M |
| 391 | CNTX | Context Therapeutics Inc. | $0.59 | $56.38M | $0.00 | -$40.23M | $-0.42 | 3.91M |
| 392 | OKYO | OKYO Pharma Limited | $1.48 | $55.38M | $0.00 | -$7.30M | $-0.20 | 140.87K |
| 393 | HYFT | MindWalk Holdings Corp. | $1.18 | $54.89M | $13.09M | -$8.70M | $-0.19 | 291.31K |
| 394 | LIXT | Lixte Biotechnology Holdings, Inc. | $4.87 | $53.03M | $0.00 | -$7.22M | $-0.42 | 495.06K |
| 395 | ELOX | Eloxx Pharmaceuticals, Inc. | $12.00 | $52.59M | $0.00 | -$17.92M | $-4.09 | 55.97K |
| 396 | GNPX | Genprex, Inc. | $7.49 | $52.07M | $0.00 | -$16.73M | $-7.27 | 30.38K |
| 397 | DWTX | Dogwood Therapeutics, Inc. | $1.54 | $51.66M | $0.00 | -$28.32M | $-2.20 | 98.86K |
| 398 | RADX | Radiopharm Theranostics Limited | $4.29 | $50.68M | $2.54M | -$26.79M | $-3.85 | 21.47K |
| 399 | MCRB | Seres Therapeutics, Inc. | $5.23 | $50.12M | $1.50M | -$46.90M | $-5.22 | 114.44K |
| 400 | VERU | Veru Inc. | $2.31 | $50.02M | $0.00 | -$14.09M | $-0.73 | 377.75K |
| 401 | ATYR | aTyr Pharma, Inc. | $0.50 | $48.84M | $190.00K | -$70.03M | $-0.73 | 1.99M |
| 402 | TIL | Instil Bio, Inc. | $7.20 | $48.83M | $0.00 | -$47.38M | $-7.04 | 16.20K |
| 403 | ALGS | Aligos Therapeutics, Inc. | $4.69 | $48.79M | $4.71M | -$90.32M | $-8.70 | 219.90K |
| 404 | ANVS | Annovis Bio, Inc. | $1.75 | $48.73M | $0.00 | -$40.92M | $-1.78 | 876.86K |
| 405 | EDSA | Edesa Biotech, Inc. | $5.66 | $46.72M | $0.00 | -$10.44M | $-1.38 | 115.55K |
| 406 | MREO | Mereo BioPharma Group plc | $0.29 | $46.67M | $500.00K | -$35.70M | $-0.22 | 1.43M |
| 407 | IBO | Impact BioMedical Inc. | $0.43 | $46.38M | $39.00K | -$12.86M | $-0.31 | 56.39K |
| 408 | MGX | Metagenomi Therapeutics, Inc. | $1.22 | $45.85M | $22.33M | -$85.89M | $-2.29 | 186.66K |
| 409 | INMB | INmune Bio Inc. | $1.72 | $45.73M | $0.00 | -$41.60M | $-1.61 | 1.13M |
| 410 | OSTX | OS Therapies Incorporated | $1.56 | $45.63M | $0.00 | -$44.20M | $-1.31 | 744.41K |
| 411 | FLNA | Filana Therapeutics, Inc. | $0.93 | $45.02M | $0.00 | -$90.97M | $-1.88 | 362.97K |
| 412 | BYSI | BeyondSpring Inc. | $1.08 | $44.41M | $0.00 | -$7.64M | $-0.19 | 26.95K |
| 413 | INKT | MiNK Therapeutics, Inc. | $10.36 | $44.24M | $0.00 | -$10.83M | $-2.38 | 19.61K |
| 414 | DYAI | Dyadic International, Inc. | $1.21 | $44.04M | $2.16M | -$7.29M | $-0.22 | 254.96K |
| 415 | MAIA | MAIA Biotechnology, Inc. | $1.28 | $41.11M | $0.00 | -$24.25M | $-0.76 | 640.28K |
| 416 | KZIA | Kazia Therapeutics Limited | $13.04 | $40.69M | $1.76M | -$35.41M | $-23.22 | 172.43K |
| 417 | TELO | Telomir Pharmaceuticals, Inc. | $1.16 | $39.88M | $0.00 | -$9.22M | $-0.28 | 130.53K |
| 418 | GRCE | Grace Therapeutics, Inc. | $2.35 | $39.79M | $0.00 | -$5.98M | $-0.38 | 236.32K |
| 419 | EXOZ | eXoZymes, Inc. | $4.70 | $39.76M | $0.00 | -$9.67M | $-1.15 | 13.29K |
| 420 | VYNE | VYNE Therapeutics Inc. | $0.92 | $39.49M | $454.00K | -$21.46M | $-0.50 | 1.27M |
| 421 | PDSB | PDS Biotechnology Corporation | $0.70 | $38.87M | $0.00 | -$33.36M | $-0.69 | 441.43K |
| 422 | DMRA | Damora Therapeutics, Inc. | $29.17 | $38.71M | $0.00 | -$235.09M | $-172.32 | 803.21K |
| 423 | VRXA | VERAXA Biotech AG | $1.86 | $37.16M | $0.00 | $6.74M | $0.26 | 832.49K |
| 424 | FTH | Faeth Therapeutics, Inc. | $27.76 | $35.95M | $-4.85M | -$184.46M | $-145.30 | 199.17K |
| 425 | NTRB | Nutriband Inc. | $2.93 | $35.62M | $1.80M | -$8.08M | $-0.68 | 13.51K |
| 426 | OTLK | Outlook Therapeutics, Inc. | $1.32 | $33.63M | $333.14K | -$60.96M | $-1.44 | 14.04M |
| 427 | GOSS | Gossamer Bio, Inc. | $0.14 | $33.36M | $55.54M | -$180.40M | $-0.79 | 18.87M |
| 428 | NNVC | NanoViricides, Inc. | $1.53 | $33.06M | $0.00 | -$8.21M | $-0.44 | 377.83K |
| 429 | GNTA | Genenta Science S.p.A. | $1.65 | $32.52M | $0.00 | -$17.57M | $-0.92 | 210.52K |
| 430 | RNXT | RenovoRx, Inc. | $0.85 | $32.50M | $1.49M | -$12.27M | $-0.33 | 195.67K |
| 431 | LTRN | Lantern Pharma Inc. | $2.87 | $32.30M | $0.00 | -$15.91M | $-1.45 | 167.52K |
| 432 | ESLA | Estrella Immunopharma, Inc. | $0.76 | $32.20M | $0.00 | -$13.25M | $-0.35 | 44.82K |
| 433 | VBIO | Valion Bio, Inc. | $0.29 | $32.18M | $1.54M | -$7.91M | $-0.11 | 593.37K |
| 434 | LONA | LeonaBio, Inc. | $7.24 | $30.96M | $0.00 | -$129.41M | $-31.56 | 32.72K |
| 435 | ABVC | ABVC BioPharma, Inc. | $1.20 | $30.54M | $0.00 | -$9.42M | $-0.42 | 169.32K |
| 436 | ACTU | Actuate Therapeutics, Inc. | $1.26 | $29.66M | $0.00 | -$21.54M | $-0.98 | 380.62K |
| 437 | KYNB | Kyntra Bio, Inc. | $7.07 | $28.61M | $7.44M | $111.45M | $27.55 | 28.80K |
| 438 | HYPD | Hyperion DeFi, Inc. | $2.64 | $28.01M | $1.04M | -$32.99M | $-2.66 | 528.04K |
| 439 | ATNM | Actinium Pharmaceuticals, Inc. | $0.89 | $27.83M | $90.00K | -$23.47M | $-0.75 | 112.88K |
| 440 | APLM | Apollomics, Inc. | $18.86 | $27.27M | $1.02M | -$226.46M | $-256.74 | 26.86K |
| 441 | BCTX | BriaCell Therapeutics Corp. | $3.72 | $26.97M | $0.00 | -$30.68M | $-9.58 | 163.15K |
| 442 | SKYE | Skye Bioscience, Inc. | $0.68 | $26.78M | $0.00 | -$57.33M | $-1.45 | 129.26K |
| 443 | CING | Cingulate Inc. | $4.84 | $26.29M | $0.00 | -$27.71M | $-4.81 | 315.08K |
| 444 | XTLB | XTL Biopharmaceuticals Ltd. | $2.90 | $25.56M | $968.00K | -$7.01M | $-0.80 | 29.76K |
| 445 | IGC | IGC Pharma, Inc. | $0.27 | $25.19M | $1.19M | -$6.55M | $-0.07 | 460.36K |
| 446 | SER | Serina Therapeutics, Inc. | $2.09 | $25.18M | $130.00K | -$21.27M | $-2.00 | 88.68K |
| 447 | PSTV | Plus Therapeutics, Inc. | $3.78 | $25.12M | $5.18M | -$11.93M | $-3.26 | 195.84K |
| 448 | CRVO | CervoMed Inc. | $2.67 | $24.72M | $2.08M | -$30.04M | $-3.25 | 11.53M |
| 449 | MRKR | Marker Therapeutics, Inc. | $1.27 | $24.53M | $2.09M | -$10.90M | $-0.67 | 61.07K |
| 450 | BRNS | Barinthus Biotherapeutics plc | $0.60 | $24.51M | $0.00 | -$52.31M | $-1.29 | 46.92K |
| 451 | TLSA | Tiziana Life Sciences Ltd | $1.02 | $24.13M | $0.00 | -$34.95M | $-0.62 | 245.58K |
| 452 | TVRD | Tvardi Therapeutics, Inc. | $2.56 | $24.01M | $2.57M | -$15.91M | $-1.74 | 4.51M |
| 453 | NXTC | NextCure, Inc. | $4.18 | $21.90M | $0.00 | -$54.66M | $-15.85 | 4.15M |
| 454 | NEUP | Neuphoria Therapeutics Inc. | $3.92 | $21.21M | $7.49M | -$16.50M | $-4.68 | 331.58K |
| 455 | ATOS | Atossa Therapeutics, Inc. | $2.41 | $20.78M | $0.00 | -$37.64M | $-4.37 | 264.65K |
| 456 | RNTX | Rein Therapeutics Inc. | $0.80 | $20.36M | $0.00 | -$75.35M | $-2.71 | 559.14K |
| 457 | EVAX | Evaxion A/S | $3.05 | $19.54M | $7.53M | -$7.71M | $-0.48 | 21.93K |
| 458 | CELU | Celularity Inc. | $0.76 | $19.45M | $26.55M | -$136.06M | $-5.30 | 126.76K |
| 459 | DARE | Daré Bioscience, Inc. | $1.26 | $18.30M | $1.16M | -$12.02M | $-0.95 | 187.10K |
| 460 | PLUR | Pluri Inc. | $1.80 | $18.05M | $1.08M | -$26.16M | $-2.90 | 35.52K |
| 461 | HOWL | Werewolf Therapeutics, Inc. | $0.36 | $17.79M | $0.00 | -$56.27M | $-1.19 | 807.48K |
| 462 | ALLR | Allarity Therapeutics, Inc. | $1.22 | $17.54M | $665.00K | -$12.30M | $-0.81 | 134.86K |
| 463 | NRSN | NeuroSense Therapeutics Ltd. | $0.66 | $16.69M | $0.00 | -$9.72M | $-0.40 | 178.48K |
| 464 | PASG | Passage Bio, Inc. | $4.90 | $15.71M | $0.00 | -$37.68M | $-11.84 | 118.36K |
| 465 | TVGN | Tevogen Bio Holdings Inc. | $4.41 | $15.37M | $0.00 | -$21.49M | $-5.96 | 20.40K |
| 466 | VRAX | Virax Biolabs Group Limited | $3.19 | $15.19M | $87.86K | -$12.22M | $-3.38 | 3.04M |
| 467 | CYCN | Cyclerion Therapeutics, Inc. | $3.60 | $15.14M | $1.99M | -$5.28M | $-1.54 | 23.93K |
| 468 | LGVN | Longeveron Inc. | $0.61 | $15.05M | $1.22M | -$22.43M | $-1.11 | 249.58K |
| 469 | GRDX | GridAI Technologies Corp. | $3.35 | $14.91M | $74.46K | -$8.69M | $-2.78 | 67.22K |
| 470 | LPCN | Lipocine Inc. | $2.19 | $14.88M | $2.00M | -$11.43M | $-1.97 | 71.38K |
| 471 | NCEL | NewcelX Ltd. | $3.80 | $14.61M | $0.00 | -$4.21M | $-2.09 | 29.22K |
| 472 | LEXX | Lexaria Bioscience Corp. | $0.57 | $13.94M | $368.00K | -$9.53M | $-0.46 | 71.15K |
| 473 | SNTI | Senti Biosciences Holdings, Inc. | $0.43 | $13.21M | $38.00K | -$51.55M | $-1.86 | 298.54K |
| 474 | BLRX | BioLineRx Ltd. | $2.86 | $12.68M | $1.40M | -$8.88M | $-2.13 | 21.95K |
| 475 | HIND | Vyome Holdings, Inc. | $2.14 | $12.67M | $152.72K | -$10.93M | $-2.94 | 16.73K |
| 476 | PHIO | Phio Pharmaceuticals Corp. | $1.07 | $12.43M | $0.00 | -$10.93M | $-1.31 | 1.11M |
| 477 | QNRX | Quoin Pharmaceuticals, Ltd. | $4.37 | $12.37M | $0.00 | -$16.98M | $-10.44 | 469.38K |
| 478 | CTXR | Citius Pharmaceuticals, Inc. | $0.53 | $11.89M | $5.61M | -$46.20M | $-2.56 | 289.27K |
| 479 | JSPR | Jasper Therapeutics, Inc. | $0.73 | $11.18M | $0.00 | -$55.65M | $-2.93 | 2.31M |
| 480 | CMMB | Chemomab Therapeutics Ltd. | $1.40 | $10.95M | $0.00 | -$8.99M | $-1.41 | 209.10K |
| 481 | XCUR | Exicure, Inc. | $1.71 | $10.90M | $0.00 | -$9.78M | $-1.55 | 483.42K |
| 482 | QNTM | Quantum BioPharma Ltd. | $2.84 | $10.88M | $0.00 | -$26.18M | $-8.45 | 132.01K |
| 483 | BIVI | BioVie Inc. | $1.44 | $10.86M | $0.00 | -$19.96M | $-3.80 | 213.36K |
| 484 | ASBP | Aspire Biopharma Holdings, Inc. | $7.21 | $10.78M | $34.55K | -$11.76M | $-8.61 | 534.41K |
| 485 | CALC | CalciMedica, Inc. | $0.72 | $10.75M | $0.00 | -$19.54M | $-1.30 | 2.37M |
| 486 | CLRB | Cellectar Biosciences, Inc. | $2.47 | $10.47M | $0.00 | -$20.84M | $-6.29 | 114.97K |
| 487 | KPRX | Kiora Pharmaceuticals, Inc. | $2.50 | $10.44M | $0.00 | -$11.06M | $-2.66 | 22.42K |
| 488 | PLRZ | Polyrizon Ltd. | $15.31 | $10.42M | $0.00 | -$4.70M | $-11.45 | 43.19K |
| 489 | COCP | Cocrystal Pharma, Inc. | $0.92 | $10.39M | $225.00K | -$9.20M | $-0.74 | 53.16K |
| 490 | TPST | Tempest Therapeutics, Inc. | $0.94 | $10.28M | $0.00 | -$43.10M | $-7.39 | 140.03K |
| 491 | GDTC | CytoMed Therapeutics Limited | $0.88 | $10.25M | $394.45K | -$4.22M | $-0.36 | 12.82K |
| 492 | GTBP | GT Biopharma, Inc. | $0.34 | $10.15M | $0.00 | -$47.82M | $-4.50 | 1.16M |
| 493 | BCDA | BioCardia, Inc. | $0.91 | $9.79M | $0.00 | -$7.78M | $-0.95 | 733.58K |
| 494 | CVM | CEL-SCI Corporation | $1.19 | $9.68M | $0.00 | -$22.70M | $-3.32 | 449.75K |
| 495 | TOVX | Theriva Biologics, Inc. | $0.22 | $8.91M | $300.00K | -$21.46M | $-1.23 | 11.81M |
| 496 | PTN | Palatin Technologies, Inc. | $8.04 | $8.83M | $12.88M | -$6.25M | $-5.92 | 19.37K |
| 497 | VTGN | Vistagen Therapeutics, Inc. | $0.23 | $8.60M | $1.27M | -$69.69M | $-1.88 | 3.31M |
| 498 | MBRX | Moleculin Biotech, Inc. | $2.08 | $8.58M | $0.00 | -$30.33M | $-12.86 | 786.13K |
| 499 | VOR | Vor Biopharma Inc. | $18.98 | $8.16M | $0.00 | -$883.08M | $-104.91 | 1.57M |
| 500 | IMRN | Immuron Limited | $1.13 | $7.74M | $9.11M | -$5.94M | $-0.98 | 49.73K |
