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Spero Therapeutics, Inc.

SPRONASDAQHealthcareBiotechnology

$1.11Today:- (-)1Y −48.64%

As of Oct 23, 2026 close

Market cap
$64.35M
P/E (TTM)
8.72
Forward P/E
-
Dividend yield
-
52-week range
$1.08$3.08
Volume (live)
-
Avg. volume (3M)
722.32K

Spero Therapeutics (SPRO) Stock Price & Financial Analysis

Spero Therapeutics Stock Price Chart

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Financial Metrics & Key Statistics

Fundamental metrics, valuation ratios, and profitability indicators

Price & Trading Activity
Day's Range$1.10 - $1.13
52-Week High$3.08
52-Week Low$1.08
Open$1.13
Volume (last close)316.55K
Average Volume (3M)722.32K
Earnings & Profitability
Revenue (TTM)42.96M
Net Income (TTM)7.38M
Free Cash Flow (TTM)19.58M
EPS (TTM)$0.13
Profit Margin17.18%
Operating Margin15.39%
Return on Equity (ROE)16.70%
Debt to Equity0.05
Dividend Information
Annual Dividend$0.00
Dividend Yield0.00%
Payout Ratio0.00%
Size & Valuation
Market Cap64.35M
Shares Outstanding57.97M
P/E Ratio (TTM)8.72
Price to Sales (P/S)1.50
Price to Book (P/B)1.46
EV/EBITDA2.41
Technical Indicators
50-Day MA$1.19
200-Day MA$2.04
1-Year Change−48.64%

Source: Market prices and company fundamentals. Data as of Oct 23, 2026. Data sources and methodology

Compare SPRO with other stocks

Spero Therapeutics at a Glance

As of the Oct 23, 2026 close, Spero Therapeutics (SPRO) has a market capitalization of $64.35M. The stock trades at 8.7× trailing earnings and 1.5× sales. Over the trailing twelve months it earned $7.38M on revenue of $42.96M (a 17.2% profit margin) and generated $19.58M of free cash flow. Revenue fell 3.4% year over year.

As of its latest reported balance sheet, it holds $50.77M in cash and securities against $2.04M of debt, a net cash position of $48.73M.

Spero Therapeutics does not currently pay a dividend.

The share price is down 48.6% over the past year. At $1.11 (the Oct 23, 2026 close) it sits near the bottom of its 52-week range of $1.08 to $3.08, below its 200-day moving average of $2.04.

Frequently Asked Questions About Spero Therapeutics

What is the current stock price for SPRO?

As of the Oct 23, 2026 close, SPRO stock trades at $1.11. The 52-week range is $1.08–$3.08, with a day range of $1.10–$1.13.

What is the P/E ratio for SPRO?

As of the Oct 23, 2026 close, Spero Therapeutics's trailing twelve-month (TTM) P/E ratio is 8.7, meaning investors pay $8.7 for every $1 of annual earnings. Spero Therapeutics operates in the Healthcare sector.

Does SPRO pay dividends?

Spero Therapeutics does not currently pay a regular dividend. The company retains its earnings to reinvest in the business. Check the Dividends tab for historical dividend information.

What do analysts recommend for SPRO?

Analyst ratings and recommendations for SPRO are displayed in the Analyst Consensus section, including buy/hold/sell distribution and 12-month price targets.

What is the market cap of SPRO?

As of the Oct 23, 2026 close, Spero Therapeutics's market capitalization is $64.3M, classifying it as a micro-cap company. Spero Therapeutics operates in the Healthcare sector within the Biotechnology industry.