Pyxis Oncology (PYXS) Cash Flow: Operating & Free Cash Flow

Pyxis Oncology Cash Flow Statement Analysis

Values in millions USD

Income Statement Balance Sheet Cash Flow Ratios

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Cash flow statement showing operating, investing, and financing activities for Pyxis Oncology, Inc. (PYXS) - Annual data in millions USD
Breakdown	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020	FY 2019
Period ending	Dec 2025	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020	Dec 2019
Operating Activities
Net Income	-79.62	-77.33	-73.79	-120.72	-75.98	-12.83	-2.77
Depreciation & Amortization	4.51	2.98	1.93	0.71	0.65	0.47	0.00
Deferred Income Tax	0.00	0.00	0.00	0.00	6.28	0.00	0.00
Stock Based Compensation	11.80	12.95	16.95	15.76	6.44	0.04	0.03
Change in Working Capital	1.94	-11.82	-11.66	4.50	6.68	1.87	0.51
Change in Accounts Payable	6.03	1.20	-3.51	-8.33	4.64	0.56	0.29
Change in Other Working Capital	-1.26	0.70	0.66	12.83	2.03	1.31	0.21
Other Operating Activities	-2.14	0.70	0.66	10.41	20.60	0.37	-0.26
Net Cash from Operating Activities	-63.50	-57.67	-70.71	-89.34	-35.33	-10.08	-2.24
Investing Activities
Capital Expenditures	-0.01	-0.24	-6.73	-6.40	-0.54	-1.48	0.00
Acquisitions	0.00	0.00	6.66	0.00	-0.05	0.00	0.00
Purchases of Investments	-107.01	-160.12	-196.83	0.00	-0.05	0.00	0.00
Sales/Maturities of Investments	165.87	168.51	92.05	0.00	0.05	0.00	0.00
Other Investing Activities	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Net Cash from Investing Activities	58.86	8.16	-104.85	-6.40	-0.59	-1.48	0.00
Financing Activities
Common Stock Issued	0.74	59.05	6.12	0.00	152.30	0.04	0.01
Common Stock Repurchased	0.15	0.24	0.00	0.00	0.00	0.00	0.00
Other Financing Activities	-0.15	-0.24	-0.45	0.18	151.75	0.03	43.90
Net Cash from Financing Activities	0.59	59.33	5.93	0.18	304.04	0.04	21.96
Summary
Net Change in Cash	-4.05	9.81	-169.63	-95.55	268.13	-11.53	19.72
Cash at Beginning of Period	20.95	11.14	180.77	276.32	8.19	19.72	0.00
Cash at End of Period	16.89	20.95	11.14	180.77	276.32	8.19	19.72
Free Cash Flow	-63.51	-57.91	-77.44	-95.73	-35.87	-11.57	-2.24
Supplemental Disclosures
Interest Paid	-	0.01	0.00	-	-	-	-
Income Taxes Paid	-	0.16	0.05	0.02	-	-	-

Source: Company financial statements from annual and quarterly filings. Data as of Jun 30, 2026. Data sources and methodology

Frequently Asked Questions About Pyxis Oncology Cash Flow

What is Pyxis Oncology's free cash flow?

Pyxis Oncology had negative free cash flow of $63.51M in fiscal 2025 (fiscal year ended Dec 31, 2025), operating cash flow of −$63.50M minus $9.00K of capital expenditures.

How much does Pyxis Oncology spend on capital expenditures?

Pyxis Oncology spent $9.00K on capital expenditures in fiscal 2025, compared with $237.00K a year earlier.

Does Pyxis Oncology pay dividends or buy back shares?

Yes. In fiscal 2025 Pyxis Oncology returned $148.00K in share buybacks to shareholders, according to its cash flow statement.

What is free cash flow?

Free cash flow is operating cash flow minus capital expenditures. It is the cash a company has left for dividends, buybacks, debt repayment or acquisitions after funding its operations and investment. Full definition