Pyxis Oncology (PYXS) Financial Statements & Analysis

Pyxis Oncology Income Statement Analysis

Values in millions USD

Income Statement Balance Sheet Cash Flow Ratios

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Pyxis Oncology, Inc. income statement - Annual data in millions USD
Breakdown	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020	FY 2019
Period ending	Dec 2025	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020	Dec 2019
Revenue & Gross Profit
Revenue	13.86	16.15	0.00	0.00	0.00	0.00	0.00
Cost of Revenue	2.39	0.48	0.00	0.00	0.00	0.44	0.00
Gross Profit	11.47	15.67	0.00	0.00	0.00	-0.44	0.00
Operating Expenses
Research & Development	73.70	58.75	49.59	86.13	51.05	9.05	1.22
Selling, General & Administrative	22.19	25.42	30.83	37.35	18.66	3.85	1.66
Operating Expenses	95.89	84.17	82.20	123.48	69.72	12.89	2.88
Operating Income	-84.42	-68.50	-82.20	-123.48	-69.72	-12.89	-2.88
Other Income/Expense
Interest Income	3.61	7.04	6.63	2.76	0.02	0.07	0.11
Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Other Income/Expense	2.58	-18.04	15.04	2.76	-6.26	0.07	0.11
Income
Income Before Tax	-78.24	-79.50	-73.79	-120.72	-75.98	-12.83	-2.77
Income Tax Expense	1.39	-2.16	0.00	0.00	0.00	0.00	0.00
Net Income	-79.62	-77.33	-73.79	-120.72	-75.98	-12.83	-2.77
Net Income - Continuous Operations	-79.62	-77.33	-73.79	-120.72	-75.98	-12.83	-2.77
Net Income - Discontinued Operations	-	-	-	-	-	-	-
EBITDA	-79.91	-65.51	-78.49	-122.77	-75.33	-12.43	-2.77
EBIT	-84.42	-68.50	-80.42	-123.48	-69.72	-12.89	-
Depreciation & Amortization	4.51	2.98	1.93	0.71	0.65	0.47	0.00
Earnings Per Share
Basic EPS	-1.00	-1.00	-2.00	-4.00	-3.00	-12.00	-
Diluted EPS	-1.00	-1.00	-2.00	-4.00	-3.00	-12.00	-
Basic Shares Outstanding	62.14	58.45	39.90	33.03	32.22	1.03	34.31
Diluted Shares Outstanding	62.14	58.45	39.90	33.03	32.22	1.03	34.31

Source: Company financial statements from annual and quarterly filings. Data as of Jun 30, 2026. Data sources and methodology

Frequently Asked Questions About Pyxis Oncology Financial Statements

What was Pyxis Oncology's revenue in fiscal 2025?

Pyxis Oncology reported revenue of $13.86M in fiscal 2025 (fiscal year ended Dec 31, 2025). That was down 14.2% from $16.15M a year earlier.

Is Pyxis Oncology profitable?

No. Pyxis Oncology reported a net loss of $79.62M in fiscal 2025. In fiscal 2024 it lost $77.33M.

What is Pyxis Oncology's operating margin?

Pyxis Oncology's operating income was −$84.42M on revenue of $13.86M in fiscal 2025, an operating margin of -609.2%, compared with -424.2% a year earlier.

What is net profit margin?

Net profit margin is net income divided by revenue. It shows how much of each dollar of sales a company keeps as profit after all costs, interest and taxes. Full definition