
XBI ETF Holdings: State Street SPDR S&P Biotech ETF
Complete portfolio holdings with allocation weights, sector breakdown, and geographic exposure for this Equity ETF. Analyze fund diversification and concentration.
Portfolio Allocations
Distribution breakdown by sector, asset type, and geographic region. Understand the fund's diversification strategy across markets and asset classes.
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Top 50 Holdings by Portfolio Weight
View ticker symbols, company names, asset types, and allocation percentages for each position
| # | Symbol | Name | Type | Weight |
|---|---|---|---|---|
| 1 | ![]() | Apellis Pharmaceuticals, Inc. | Stock | 1.83% |
| 2 | ![]() | Moderna, Inc | Stock | 1.77% |
| 3 | ![]() | Halozyme Therapeutics, Inc | Stock | 1.58% |
| 4 | ![]() | Vaxcyte, Inc | Stock | 1.56% |
| 5 | ![]() | Revolution Medicines, Inc | Stock | 1.56% |
| 6 | ![]() | Mirum Pharmaceuticals Inc | Stock | 1.55% |
| 7 | ![]() | Gilead Sciences, Inc | Stock | 1.55% |
| 8 | ![]() | Amicus Therapeutics, Inc | Stock | 1.52% |
| 9 | ![]() | Alkermes plc | Stock | 1.48% |
| 10 | ![]() | Praxis Precision Medicines, Inc | Stock | 1.47% |
| 11 | ![]() | Amgen Inc | Stock | 1.47% |
| 12 | ![]() | Krystal Biotech, Inc | Stock | 1.41% |
| 13 | ![]() | Madrigal Pharmaceuticals, Inc. | Stock | 1.39% |
| 14 | ![]() | Incyte Corporation | Stock | 1.36% |
| 15 | ![]() | TG Therapeutics, Inc. | Stock | 1.36% |
| 16 | ![]() | BioMarin Pharmaceutical Inc | Stock | 1.34% |
| 17 | ![]() | Insmed Incorporated | Stock | 1.34% |
| 18 | ![]() | Ionis Pharmaceuticals, Inc | Stock | 1.34% |
| 19 | ![]() | Regeneron Pharmaceuticals, Inc | Stock | 1.33% |
| 20 | ![]() | Biogen Inc | Stock | 1.32% |
| 21 | ![]() | Roivant Sciences Ltd | Stock | 1.32% |
| 22 | ![]() | Vertex Pharmaceuticals Incorporated | Stock | 1.30% |
| 23 | ![]() | Exelixis, Inc | Stock | 1.30% |
| 24 | ![]() | Celcuity LLC | Stock | 1.29% |
| 25 | ![]() | Scholar Rock Holding Corporation | Stock | 1.29% |
| 26 | ![]() | Avidity Biosciences Inc | Stock | 1.29% |
| 27 | ![]() | Apogee Therapeutics, Inc. | Stock | 1.28% |
| 28 | ![]() | Exact Sciences Corporation | Stock | 1.28% |
| 29 | ![]() | Cytokinetics, Incorporated | Stock | 1.26% |
| 30 | ![]() | Rhythm Pharmaceuticals, Inc | Stock | 1.25% |
| 31 | ![]() | GRAIL, LLC | Stock | 1.25% |
| 32 | ![]() | United Therapeutics Corporation | Stock | 1.25% |
| 33 | ![]() | PTC Therapeutics, Inc | Stock | 1.23% |
| 34 | ![]() | Arrowhead Pharmaceuticals, Inc. | Stock | 1.23% |
| 35 | ![]() | Summit Therapeutics Inc. | Stock | 1.23% |
| 36 | ![]() | AbbVie Inc | Stock | 1.23% |
| 37 | ![]() | Protagonist Therapeutics, Inc. | Stock | 1.22% |
| 38 | ![]() | Nuvalent, Inc. | Stock | 1.20% |
| 39 | ![]() | Travere Therapeutics, Inc. | Stock | 1.20% |
| 40 | ![]() | Twist Bioscience Corporation | Stock | 1.20% |
| 41 | ![]() | Kymera Therapeutics, Inc. | Stock | 1.18% |
| 42 | ![]() | BridgeBio Pharma, Inc. | Stock | 1.18% |
| 43 | ![]() | Natera, Inc. | Stock | 1.17% |
| 44 | ![]() | Neurocrine Biosciences, Inc. | Stock | 1.16% |
| 45 | ![]() | Alnylam Pharmaceuticals, Inc. | Stock | 1.16% |
| 46 | ![]() | CG Oncology, Inc. Common stock | Stock | 1.13% |
| 47 | ![]() | Arcellx Inc | Stock | 1.01% |
| 48 | ![]() | ACADIA Pharmaceuticals Inc | Stock | 1.01% |
| 49 | ![]() | ADMA Biologics, Inc | Stock | 1.00% |
| 50 | ![]() | CRISPR Therapeutics AG | Stock | 1.00% |
Frequently Asked Questions About State Street SPDR S&P Biotech ETF Holdings
What are the top holdings in XBI?
State Street SPDR S&P Biotech ETF (XBI) holds 156 securities. View the complete list of top holdings sorted by portfolio weight, showing each security's ticker symbol, company name, asset type, and allocation percentage.
How concentrated is XBI's portfolio?
Portfolio concentration is measured by the weight of top holdings. A concentrated portfolio has fewer large positions with higher individual weights, while a diversified portfolio distributes holdings more evenly. Review XBI's holdings table to analyze concentration risk.
What is XBI's sector allocation?
The Sector Allocation chart shows how XBI distributes investments across different industries like Technology, Healthcare, Financials, and more. This sector exposure helps understand the fund's industry diversification strategy.
What countries does XBI invest in?
XBI's geographic exposure is shown in the Countries tab under Portfolio Allocations. This reveals the fund's international diversification and exposure to different regions and global markets.
How diversified is XBI ETF?
XBI's diversification can be assessed by reviewing its 156 holdings, sector allocation, and geographic exposure. A well-diversified ETF spreads investments across multiple securities, sectors, and regions to reduce concentration risk.

















































