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Denali Therapeutics Inc.

DNLINASDAQHealthcareBiotechnology

$17.61Today:- (-)1Y +10.08%

As of Oct 16, 2026 close

Market cap
$3.44B
P/E (TTM)
-
Forward P/E
-
Dividend yield
-
52-week range
$13.75$27.30
Volume (live)
-
Avg. volume (3M)
1.83M

Denali Therapeutics (DNLI) Income Statement

In fiscal 2025 (fiscal year ended Dec 31, 2025), Denali Therapeutics posted a net loss of $512.54M, compared with a net loss of $422.77M a year earlier. In the most recent quarter, Q2 fiscal 2026 (ended Jun 30, 2026), revenue was $3.60M.

Denali Therapeutics Income Statement Analysis

Values in millions USD

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Denali Therapeutics Inc. income statement - Annual data in millions USD
BreakdownFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017
Period endingDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017
Revenue & Gross Profit
Revenue0.000.00330.53108.4648.66335.6626.68129.160.00
Cost of Revenue418.78396.440.00358.730.000.000.000.003.08
Gross Profit-11.18-396.44330.53-250.2748.66335.6626.68129.16-3.08
Operating Expenses
Research & Development418.78396.44423.88358.73265.35212.62193.38143.1874.46
Selling, General & Administrative136.56105.44103.3590.4879.0660.3346.4832.3515.68
Operating Expenses555.34501.88527.23449.21344.41272.94239.86175.5390.14
Operating Income-555.34-501.88-196.70-340.74-295.7562.72-213.18-46.37-90.14
Other Income/Expense
Interest Income42.9064.6451.5114.774.609.2415.2210.131.96
Interest Expense0.00-0.300.000.000.000.000.000.001.96
Other Income/Expense42.9014.5451.5114.774.609.2415.2210.131.96
Income
Income Before Tax-512.44-422.71-145.19-325.97-291.1671.96-197.97-36.24-88.19
Income Tax Expense0.100.070.030.02-0.580.82-0.350.000.00
Net Income-512.54-422.77-145.22-325.99-290.5871.14-197.61-36.24-88.19
Net Income - Continuous Operations-512.54-422.77-145.22-325.99-290.5871.14-197.61-36.24-88.19
Net Income - Discontinued Operations---------
EBITDA-540.53-492.89-128.47-330.36-282.5671.25-205.19-38.96-87.06
EBIT-555.34-501.88-196.70-340.74-295.7562.72---
Depreciation & Amortization14.818.9916.7310.388.598.537.997.423.08
Earnings Per Share
Basic EPS-3.00-3.00-1.00-3.00-2.001.00-2.00--6.00
Diluted EPS-3.00-3.00-1.00-3.00-2.001.00-2.00--6.00
Basic Shares Outstanding172.65164.47137.37125.53121.52108.9795.6192.6214.96
Diluted Shares Outstanding172.65164.47137.37125.53121.52112.7095.6192.6214.96

Source: Company financial statements from annual and quarterly filings. Data as of Jun 30, 2026. Data sources and methodology

Frequently Asked Questions About Denali Therapeutics Financial Statements

Is Denali Therapeutics profitable?

No. Denali Therapeutics reported a net loss of $512.54M in fiscal 2025. In fiscal 2024 it lost $422.77M.

What is net profit margin?

Net profit margin is net income divided by revenue. It shows how much of each dollar of sales a company keeps as profit after all costs, interest and taxes. Full definition