About Pliant Therapeutics
Pliant Therapeutics, Inc., a biopharmaceutical company, discovers, develops, and commercializes novel therapies for the treatment of fibrosis and related diseases.
The company’s lead candidate includes bexotegrast, an oral, small-molecule, dual selective inhibitor of αvß6 and αvß1 integrins, which has completed phase 2a trial for primary sclerosing cholangitis.
It also develops PLN-1474, an oral, small-molecule selective inhibitor of αvß1 for the treatment of liver fibrosis associated with nonalcoholic steatohepatitis; PLN-101095, a dual inhibitor of integrins αvß8 and αvß1 for the treatment of solid tumors; and PLN-101325, a phase 1-ready program for treatment of the muscular dystrophies, including duchenne muscular dystrophy.
Pliant Therapeutics, Inc. was incorporated in 2015 and is headquartered in South San Francisco, California.