Silence Therapeutics plc

SLNNASDAQHealthcareBiotechnology

$19.78- (-)1Y +171.17%

As of Oct 26, 2026 close

Market cap: $934.34M
P/E (TTM): -
Forward P/E: -
Dividend yield: -
52-week range: $4.19$19.65
Volume (live): -
Avg. volume (3M): 4.15M

Silence Therapeutics plc (SLN) Analyst Forecast

Analyst consensus ratings, 12-month price targets, and expert recommendations for Silence Therapeutics plc stock.

Analyst Consensus Rating

Investment consensus from 6 professional research analysts

Consensus Rating

Hold

Based on 6 unique analysts

(10 total ratings in last 90 days)

Medium Confidence∞:1 Buy/Sell

Average Price Target

$23.00

+16.28% upside

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Strong Sell

Sell

Hold

Buy

Strong Buy

Latest SLN Analyst Ratings & Recommendations

Recent analyst recommendations with rating changes and price target updates (last 90 days)

Date	Analyst	Firm	Action	Rating	Price Target
Oct 21, 2026	Patrick Trucchio	HC Wainwright	Downgrades	Hold	$75.00 → $20.00 −55.00 (−73.3%)
Oct 20, 2026	Zacks Equity Research	Zacks Equity Research	Initiates Coverage	Buy	-
Oct 19, 2026	Keay Nakae	Chardan Capital	Downgrades	Hold	$27.00 → $20.00 −7.00 (−25.9%)
Oct 19, 2026	Myles Minter	William Blair	Downgrades	Hold	-
Oct 19, 2026	Andrew Tsai	Jefferies	Downgrades	Hold	$35.00 → $20.00 −15.00 (−42.9%)
Sep 21, 2026	Patrick Trucchio	HC Wainwright	Maintains	Buy	$75.00
Sep 10, 2026	Myles Minter	William Blair	Reiterates	Buy	-
Aug 17, 2026	Keay Nakae	Chardan Capital	Maintains	Buy	-
Aug 14, 2026	Zacks Equity Research	Zacks Equity Research	Initiates Coverage	Buy	-
Aug 11, 2026	Michael Ulz	Morgan Stanley	Reiterates	Buy	$25.00 → $32.00 +7.00 (+28.0%)

Patrick Trucchio

HC Wainwright

HoldDowngrades

$75.00 → $20.00

Oct 21

Zacks Equity Research

BuyInitiates Coverage

Oct 20

Keay Nakae

Chardan Capital

HoldDowngrades

$27.00 → $20.00

Oct 19

Myles Minter

William Blair

HoldDowngrades

Oct 19

Andrew Tsai

Jefferies

HoldDowngrades

$35.00 → $20.00

Oct 19

Patrick Trucchio

HC Wainwright

BuyMaintains

$75.00

Sep 21

Myles Minter

William Blair

BuyReiterates

Sep 10

Keay Nakae

Chardan Capital

BuyMaintains

Aug 17

Zacks Equity Research

BuyInitiates Coverage

Aug 14

Michael Ulz

Morgan Stanley

BuyReiterates

$25.00 → $32.00

Aug 11

Source: Professional analyst ratings and price targets from the last 90 days. Data as of Oct 21, 2026. Data sources and methodology

Frequently Asked Questions

What is the analyst consensus rating for SLN?

The analyst consensus rating for SLN is Hold, based on the latest ratings from 6 analysts over the last 90 days.

What is the average price target for SLN?

The average 12-month price target for SLN is $23.00, representing an upside of 16.3% from the Oct 26, 2026 close of $19.78.

What do analyst ratings mean?

Analyst ratings indicate investment recommendations: Strong Buy and Buy are bullish signals suggesting the stock may outperform. Hold means the stock is fairly valued. Sell and Strong Sell are bearish signals suggesting potential underperformance. These ratings are based on fundamental analysis and valuation models.

What is a price target?

A price target is an analyst's projection of a stock's fair value over a specific timeframe, typically 12 months. Analysts use fundamental analysis, financial modeling, and industry comparisons to estimate where the stock should trade. Price targets can range from low (conservative) to high (optimistic) estimates.