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Ionis Pharmaceuticals, Inc.

IONSNASDAQHealthcareBiotechnology

$43.91Today:- (-)1Y −38.59%

As of Oct 22, 2026 close

Market cap
$7.26B
P/E (TTM)
-
Forward P/E
-
Dividend yield
-
52-week range
$42.08$86.74
Volume (live)
-
Avg. volume (3M)
3.80M

Ionis Pharmaceuticals, Inc. (IONS) Analyst Forecast

Analyst consensus ratings, 12-month price targets, and expert recommendations for Ionis Pharmaceuticals, Inc. stock.

Analyst Consensus Rating

Investment consensus from 22 professional research analysts

Consensus Rating

Buy
Based on 22 unique analysts
(26 total ratings in last 90 days)
Very High Confidence17.0:1 Buy/Sell

Average Price Target

$83.89
+91.05% upside

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Strong Sell
Sell
Hold
Buy
Strong Buy

Latest IONS Analyst Ratings & Recommendations

Recent analyst recommendations with rating changes and price target updates (last 90 days)

Joon Lee
Truist
BuyInitiates
$46.00 → $88.00
Mitchell Kapoor
HC Wainwright
BuyReiterates
$100.00
Jason Gerberry
BofA Securities
BuyMaintains
$91.00
Luca Issi
RBC Capital
BuyMaintains
$85.00
David Lebowitz
BMO Capital
HoldMaintains
$54.00
Justin Kim
Oppenheimer
BuyMaintains
$85.00
Gary Nachman
Canaccord Genuity
BuyReiterates
$85.00
Mitchell Kapoor
HC Wainwright
BuyReiterates
$100.00
Yaron Werber
TD Cowen
BuyReiterates
$84.00
Joseph Stringer
Needham
BuyMaintains
$86.00
Myles Minter
William Blair
BuyMaintains
-
Jessica Fye
JP Morgan
BuyReiterates
$70.00
Eliana Merle
Barclays
BuyMaintains
$85.00
Kinjel Shah
Zacks Equity Research
SellInitiates Coverage
-
Zacks Equity Research
Zacks Equity Research
HoldInitiates Coverage
-
Debjit Chattopadhyay
Guggenheim
BuyMaintains
$89.00 → $80.00
Salveen Richter
Goldman Sachs
HoldMaintains
$69.00 → $56.00
Michael Ulz
Morgan Stanley
BuyInitiates Coverage
$104.00
Jason Gerberry
BofA Securities
BuyMaintains
$93.00 → $91.00
Tiago Fauth
Raymond James
BuyMaintains
$87.00 → $84.00
David Lebowitz
BMO Capital
HoldMaintains
$60.00 → $61.00
Eric Joseph
Citi
BuyMaintains
$100.00
Allison Bratzel
Piper Sandler
BuyMaintains
$94.00
Yanan Zhu
Wells Fargo
BuyMaintains
$95.00
Paul Matteis
Stifel Nicolaus
HoldMaintains
$86.00 → $68.00
Luca Issi
RBC Capital
BuyReiterates
$85.00

Source: Professional analyst ratings and price targets from the last 90 days. Data as of Oct 14, 2026. Data sources and methodology

Frequently Asked Questions

What is the analyst consensus rating for IONS?

The analyst consensus rating for IONS is Buy, based on the latest ratings from 22 analysts over the last 90 days.

What is the average price target for IONS?

The average 12-month price target for IONS is $83.89, representing an upside of 91.0% from the Oct 22, 2026 close of $43.91.

What do analyst ratings mean?

Analyst ratings indicate investment recommendations: Strong Buy and Buy are bullish signals suggesting the stock may outperform. Hold means the stock is fairly valued. Sell and Strong Sell are bearish signals suggesting potential underperformance. These ratings are based on fundamental analysis and valuation models.

What is a price target?

A price target is an analyst's projection of a stock's fair value over a specific timeframe, typically 12 months. Analysts use fundamental analysis, financial modeling, and industry comparisons to estimate where the stock should trade. Price targets can range from low (conservative) to high (optimistic) estimates.