Prime Medicine (PRME) Balance Sheet: Assets & Liabilities

Prime Medicine (PRME) Balance Sheet

As of Dec 31, 2025 (end of fiscal 2025), Prime Medicine reported total assets of $342.73M and total liabilities of $221.87M. Shareholders' equity was $120.87M, down 21.1% from $153.15M a year earlier. Total debt stood at $116.43M against $177.68M in cash and short-term investments, a net cash position of $61.25M. That puts debt-to-equity at 0.96, compared with 0.27 a year earlier.

Prime Medicine Balance Sheet Analysis

Values in billions USD

Income Statement Balance Sheet Cash Flow Ratios

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Balance sheet showing assets, liabilities, and shareholders' equity for Prime Medicine, Inc. (PRME) - Annual data in billions USD
Breakdown	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020	FY 2019
Period ending	Dec 2025	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020	Dec 2019
Current Assets
Cash and Cash Equivalents	0.06	0.18	0.04	0.19	0.19	0.04	0.01
Short-Term Investments	0.11	0.01	0.08	0.11	0.08	0.02	0.00
Cash & Short-Term Investments	0.18	0.19	0.12	0.29	0.27	0.05	0.01
Accounts Receivable	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Inventory	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Other Current Assets	0.00	0.02	0.02	0.00	0.00	0.00	0.00
Total Current Assets	0.18	0.21	0.14	0.30	0.27	0.05	0.01
Non-Current Assets
Property, Plant & Equipment (Net)	0.15	0.07	0.04	0.05	0.02	0.00	0.00
Other Non-Current Assets	0.01	0.01	0.01	0.02	0.02	0.00	0.00
Total Non-Current Assets	0.16	0.09	0.05	0.06	0.03	0.00	0.00
Total Assets	0.34	0.30	0.19	0.36	0.30	0.05	0.01
Current Liabilities
Accounts Payable	0.01	0.01	0.02	0.00	0.00	0.00	0.00
Short-Term Debt	0.01	0.00	0.01	0.01	0.01	0.00	0.00
Accrued Liabilities	0.01	0.02	0.01	0.00	0.03	0.00	-
Deferred Revenue	0.01	0.01	0.00	0.00	0.00	0.00	0.00
Other Current Liabilities	0.01	0.02	0.03	0.01	0.01	0.02	0.01
Total Current Liabilities	0.04	0.04	0.06	0.03	0.06	0.02	0.01
Non-Current Liabilities
Long-Term Debt	0.11	0.04	0.00	0.02	0.00	0.00	0.00
Deferred Tax Liabilities	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Other Non-Current Liabilities	0.08	0.01	0.00	0.00	0.00	0.00	0.00
Total Non-Current Liabilities	0.18	0.11	0.00	0.02	0.00	0.00	0.00
Total Liabilities	0.22	0.14	0.06	0.04	0.06	0.02	0.01
Stockholders' Equity
Common Stock	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Retained Earnings	-0.89	-0.69	-0.49	-0.29	-0.17	-0.01	0.00
Accumulated Other Comprehensive Income	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Additional Paid-in Capital	1.01	0.84	0.62	0.61	0.02	0.01	0.00
Shares Outstanding	0.18	0.13	0.10	0.10	0.10	-	-
Total Stockholders' Equity	0.12	0.15	0.13	0.32	0.24	0.03	0.00
Total Liabilities & Equity	0.34	0.30	0.19	0.36	0.30	0.05	0.01

Source: Company financial statements from annual and quarterly filings. Data as of Jun 30, 2026. Data sources and methodology

Frequently Asked Questions About Prime Medicine Balance Sheet

How much debt does Prime Medicine have?

Prime Medicine had total debt of $116.43M as of Dec 31, 2025, against $177.68M in cash and short-term investments. Its debt-to-equity ratio was 0.96. Total debt was $40.79M a year earlier.

What are Prime Medicine's total assets?

Prime Medicine reported total assets of $342.73M as of Dec 31, 2025, up 15.2% from $297.51M a year earlier. Total liabilities were $221.87M.

What is Prime Medicine's shareholders' equity?

Prime Medicine's shareholders' equity was $120.87M as of Dec 31, 2025, or about $0.67 of book value per share.

What is the debt-to-equity ratio?

The debt-to-equity ratio divides a company's total debt by its shareholders' equity. It shows how much of the business is financed with borrowed money; normal levels vary widely by industry. Full definition