Prime Medicine (PRME) Financial Statements & Analysis

Prime Medicine (PRME) Income Statement

Prime Medicine reported revenue of $4.63M in fiscal 2025 (fiscal year ended Dec 31, 2025), up 55.3% from $2.98M a year earlier. Prime Medicine posted a net loss of $201.14M, compared with a net loss of $195.88M a year earlier. Gross margin was -58.1% and operating margin -4498.1%. In the most recent quarter, Q2 fiscal 2026 (ended Jun 30, 2026), revenue was $1.15M, up 3.5% from the same quarter a year earlier.

Prime Medicine Income Statement Analysis

Values in millions USD

Income Statement Balance Sheet Cash Flow Ratios

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Prime Medicine, Inc. income statement - Annual data in millions USD
Breakdown	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020	FY 2019
Period ending	Dec 2025	Dec 2024	Dec 2023	Dec 2022	Dec 2021	Dec 2020	Dec 2019
Revenue & Gross Profit
Revenue	4.63	2.98	0.00	0.00	0.00	5.21	0.00
Cost of Revenue	7.32	155.29	0.00	86.73	0.00	2.98	2.76
Gross Profit	-2.69	2.98	0.00	-86.73	0.00	2.23	-2.76
Operating Expenses
Research & Development	160.64	155.29	147.91	86.73	70.55	2.98	0.92
Selling, General & Administrative	52.35	50.16	43.39	29.82	13.92	3.16	1.25
Operating Expenses	205.66	205.45	204.79	116.54	84.47	3.16	2.17
Operating Income	-208.35	-202.47	-204.79	-116.54	-84.47	-0.93	-2.17
Other Income/Expense
Interest Income	4.15	3.52	0.00	0.00	0.00	0.00	0.00
Interest Expense	0.00	0.00	0.00	0.00	0.00	0.00	0.00
Other Income/Expense	7.21	3.06	6.38	-6.23	-81.38	-0.61	0.00
Income
Income Before Tax	-201.14	-195.88	-198.41	-122.77	-165.85	-1.54	-2.53
Income Tax Expense	0.00	0.00	-0.28	0.95	-0.49	1.87	0.00
Net Income	-201.14	-195.88	-198.13	-142.01	-165.37	-3.41	-2.53
Net Income - Continuous Operations	-201.14	-195.88	-198.13	-121.82	-165.37	-3.41	-2.53
Net Income - Discontinued Operations	-	-	-	-	-	-	-
EBITDA	-195.76	-196.34	-186.64	-114.32	-165.29	-0.89	-2.17
EBIT	-208.35	-202.47	-191.29	-116.54	-84.47	-0.93	-
Depreciation & Amortization	5.38	6.13	4.65	2.22	0.57	0.04	6.52
Earnings Per Share
Basic EPS	-1.00	-2.00	-2.00	-4.00	-2.00	-	-
Diluted EPS	-1.00	-2.00	-2.00	-4.00	-2.00	-	-
Basic Shares Outstanding	148.76	118.60	90.97	33.89	95.73	95.73	95.73
Diluted Shares Outstanding	148.76	118.60	90.97	33.89	95.73	95.73	95.73

Source: Company financial statements from annual and quarterly filings. Data as of Jun 30, 2026. Data sources and methodology

Frequently Asked Questions About Prime Medicine Financial Statements

What was Prime Medicine's revenue in fiscal 2025?

Prime Medicine reported revenue of $4.63M in fiscal 2025 (fiscal year ended Dec 31, 2025). That was up 55.3% from $2.98M a year earlier.

Is Prime Medicine profitable?

No. Prime Medicine reported a net loss of $201.14M in fiscal 2025. In fiscal 2024 it lost $195.88M.

What is Prime Medicine's operating margin?

Prime Medicine's operating income was −$208.35M on revenue of $4.63M in fiscal 2025, an operating margin of -4498.1%, compared with -6787.4% a year earlier.

What is net profit margin?

Net profit margin is net income divided by revenue. It shows how much of each dollar of sales a company keeps as profit after all costs, interest and taxes. Full definition